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Semi-supervised learning has been employed to alleviate the need for extensive labeled data for histopathology image segmentation, but existing methods struggle with noisy pseudo-labels due to ambiguous gland boundaries and morphological…

Computer Vision and Pattern Recognition · Computer Science 2025-09-18 Nguyen Lan Vi Vu , Thanh-Huy Nguyen , Thien Nguyen , Daisuke Kihara , Tianyang Wang , Xingjian Li , Min Xu

The significant variability in cell size and shape continues to pose a major obstacle in computer-assisted cancer detection on gigapixel Whole Slide Images (WSIs), due to cellular heterogeneity. Current CNN-Transformer hybrids use static…

Image and Video Processing · Electrical Eng. & Systems 2026-03-24 Gia Huy Thai , Hoang-Nguyen Vu , Anh-Minh Phan , Quang-Thinh Ly , Tram Dinh , Thi-Ngoc-Truc Nguyen , Nhat Ho

Breast cancer is one of the most common cancers among women globally, with early diagnosis and precise classification being crucial. With the advancement of deep learning and computer vision, the automatic classification of breast tissue…

Image and Video Processing · Electrical Eng. & Systems 2025-01-20 Jiacheng Hao , Yiqing Liu , Siqi Zeng , Yonghong He

Cancer segmentation in whole-slide images is a fundamental step for viable tumour burden estimation, which is of great value for cancer assessment. However, factors like vague boundaries or small regions dissociated from viable tumour areas…

Image and Video Processing · Electrical Eng. & Systems 2021-09-28 Yibao Sun , Giussepi Lopez , Yaqi Wang , Xingru Huang , Huiyu Zhou , Qianni Zhang

Histopathological cancer diagnostics has become more complex, and the increasing number of biopsies is a challenge for most pathology laboratories. Thus, development of automatic methods for evaluation of histopathological cancer sections…

Image and Video Processing · Electrical Eng. & Systems 2021-12-08 André Pedersen , Erik Smistad , Tor V. Rise , Vibeke G. Dale , Henrik S. Pettersen , Tor-Arne S. Nordmo , David Bouget , Ingerid Reinertsen , Marit Valla

With the rapid development of computational pathology, many AI-assisted diagnostic tasks have emerged. Cellular nuclei segmentation can segment various types of cells for downstream analysis, but it relies on predefined categories and lacks…

Computer Vision and Pattern Recognition · Computer Science 2025-03-03 Chunlin Zhong , Shuang Hao , Junhua Wu , Xiaona Chang , Jiwei Jiang , Xiu Nie , He Tang , Xiang Bai

The escalating global cancer burden underscores the critical need for precise diagnostic tools in oncology. This research employs deep learning to enhance lesion segmentation in PET/CT imaging, utilizing a dataset of 900 whole-body…

Computer Vision and Pattern Recognition · Computer Science 2024-09-17 Jiayi Liu , Qiaoyi Xue , Youdan Feng , Tianming Xu , Kaixin Shen , Chuyun Shen , Yuhang Shi

Cancer is a heterogeneous disease with different combinations of genetic and epigenetic alterations driving the development of cancer in different individuals. While these alterations are believed to converge on genes in key cellular…

Quantitative Methods · Quantitative Biology 2015-03-31 Mark D. M. Leiserson , Hsin-Ta Wu , Fabio Vandin , Benjamin J. Raphael

Despite the great progress made by deep CNNs in image semantic segmentation, they typically require a large number of densely-annotated images for training and are difficult to generalize to unseen object categories. Few-shot segmentation…

Computer Vision and Pattern Recognition · Computer Science 2020-02-10 Kaixin Wang , Jun Hao Liew , Yingtian Zou , Daquan Zhou , Jiashi Feng

This work proposes a novel approach beyond supervised learning for effective pathological image analysis, addressing the challenge of limited robust labeled data. Pathological diagnosis of diseases like cancer has conventionally relied on…

Computer Vision and Pattern Recognition · Computer Science 2024-10-23 Joonhyeon Song , Seohwan Yun , Seongho Yoon , Joohyeok Kim , Sangmin Lee

Cancer is an epidemic worldwide. At present one in four persons has cancer and this statistic will change to one in a two person in the near future. It is now known that war against cancer is the early, curable detection and treatment.…

Tissues and Organs · Quantitative Biology 2017-10-03 Shiva Bhandari , Sri Choudannavar , Ethan Avery , Peeyush Sahay , Prabhakar Pradhan

Learning to segmentation without large-scale samples is an inherent capability of human. Recently, Segment Anything Model (SAM) performs the significant zero-shot image segmentation, attracting considerable attention from the computer…

Image and Video Processing · Electrical Eng. & Systems 2023-12-22 Chuanfei Hu , Tianyi Xia , Shenghong Ju , Xinde Li

Ambiguous Medical Image Segmentation (AMIS) is significant to address the challenges of inherent uncertainties from image ambiguities, noise, and subjective annotations. Existing conditional variational autoencoder (cVAE)-based methods…

Computer Vision and Pattern Recognition · Computer Science 2026-03-16 Xiangyu Li , Chenglin Wang , Qiantong Shen , Fanding Li , Wei Wang , Kuanquan Wang , Yi Shen , Baochun Zhao , Gongning Luo

Accurate segmentation of ovarian tumors from medical images is crucial for early diagnosis, treatment planning, and patient management. However, the diverse morphological characteristics and heterogeneous appearances of ovarian tumors pose…

Image and Video Processing · Electrical Eng. & Systems 2024-07-09 Yifan Gao , Wei Xia , Wenkui Wang , Xin Gao

In this study, the main objective is to develop an algorithm capable of identifying and delineating tumor regions in breast ultrasound (BUS) and mammographic images. The technique employs two advanced deep learning architectures, namely…

Image and Video Processing · Electrical Eng. & Systems 2024-02-14 Mohsen Ahmadi , Masoumeh Farhadi Nia , Sara Asgarian , Kasra Danesh , Elyas Irankhah , Ahmad Gholizadeh Lonbar , Abbas Sharifi

Volumetric segmentation is important in medical imaging, but current methods face challenges like requiring lots of manual annotations and being tailored to specific tasks, which limits their versatility. General segmentation models used…

Computer Vision and Pattern Recognition · Computer Science 2024-10-28 Zifan Chen , Xinyu Nan , Jiazheng Li , Jie Zhao , Haifeng Li , Ziling Lin , Haoshen Li , Heyun Chen , Yiting Liu , Lei Tang , Li Zhang , Bin Dong

Images remain the largest data source in the field of healthcare. But at the same time, they are the most difficult to analyze. More than often, these images are analyzed by human experts such as pathologists and physicians. But due to…

Image and Video Processing · Electrical Eng. & Systems 2021-10-11 Dikshant Sagar

Pancreatic cancer, characterized by its notable prevalence and mortality rates, demands accurate lesion delineation for effective diagnosis and therapeutic interventions. The generalizability of extant methods is frequently compromised due…

Image and Video Processing · Electrical Eng. & Systems 2025-05-06 Jun Li , Yijue Zhang , Haibo Shi , Minhong Li , Qiwei Li , Xiaohua Qian

The integration of multi-modal data, such as pathological images and genomic data, is essential for understanding cancer heterogeneity and complexity for personalized treatments, as well as for enhancing survival predictions. Despite the…

Quantitative Methods · Quantitative Biology 2023-01-09 Lin Qiu , Aminollah Khormali , Kai Liu

The accurate segmentation of breast tumors is an important prerequisite for lesion detection, which has significant clinical value for breast tumor research. The mainstream deep learning-based methods have achieved a breakthrough. However,…

Image and Video Processing · Electrical Eng. & Systems 2023-11-21 Hongjiang Guo , Shengwen Wang , Hao Dang , Kangle Xiao , Yaru Yang , Wenpei Liu , Tongtong Liu , Yiying Wan