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Field induced assembly of reconfigurable structures with complex hierarchical configurations has recently become an area of intense research with the promise for exciting applications in programmable self-assembly and nano/microstructure…

Soft Condensed Matter · Physics 2026-01-14 Indira Barros , Sayanth Ramachandran , Indrani Chakraborty

At what level does selective pressure effectively act? When considering the reproductive dynamics of interacting and mutating agents, it has long been debated whether selection is better understood by focusing on the individual or if…

Populations and Evolution · Quantitative Biology 2023-11-02 Hardik Rajpal , Clem von Stengel , Pedro A. M. Mediano , Fernando E. Rosas , Eduardo Viegas , Pablo A. Marquet , Henrik J. Jensen

Controlling the size and shape of assembled structures is a fundamental challenge in self-assembly, and is highly relevant in material design and biology. Here, we show that specific, but promiscuous, short-range binding interactions make…

Soft Condensed Matter · Physics 2025-07-08 Maximilian C. Hübl , Carl P. Goodrich

Self-assembly is one of the prevalent strategies used by living systems to fabricate ensembles of precision nanometer-scale structures and devices. The push for analogous approaches to create synthetic nanomaterials has led to the…

We introduce a novel ensemble approach for feature selection based on hierarchical stacking for non-stationarity and/or a limited number of samples with a large number of features. Our approach exploits the co-dependency between features…

Machine Learning · Computer Science 2024-10-08 Aysin Tumay , Mustafa E. Aydin , Ali T. Koc , Suleyman S. Kozat

Polypeptides can self-assemble into hierarchically organized fibrils consisting of a stack of individually folded polypeptides driven together by hydrophobic interaction. Using a coarse grained model, we systematically studied this…

Soft Condensed Matter · Physics 2013-07-31 Ran Ni , Sanne Abeln , Marieke Schor , Martien A. Cohen Stuart , Peter G. Bolhuis

Nanoparticles with "sticky patches" have long been proposed as building blocks for the self-assembly of complex structures. The synthetic realizability of such patchy particles, however, greatly lags behind predictions of patterns they…

Soft Condensed Matter · Physics 2013-10-03 Michael Grünwald , Phillip L. Geissler

Formation of highly ordered structures usually needs to overcome a high free-energy barrier that is greatly beyond the ability of thermodynamic fluctuation, such that the system would be easily trapped into a state with many defects and the…

Materials Science · Physics 2020-01-08 Yunfei Du , Huijun Jiang , Zhonghuai Hou

It is well known that many complex systems, both in technology and nature, exhibit hierarchical modularity: smaller modules, each of them providing a certain function, are used within larger modules that perform more complex functions. What…

Neural and Evolutionary Computing · Computer Science 2018-08-07 Payam Siyari , Bistra Dilkina , Constantine Dovrolis

This paper considers networks where relationships between nodes are represented by directed dissimilarities. The goal is to study methods for the determination of hierarchical clusters, i.e., a family of nested partitions indexed by a…

Machine Learning · Computer Science 2014-09-03 Gunnar Carlsson , Facundo Mémoli , Alejandro Ribeiro , Santiago Segarra

The cornerstone of structural biology is the unique relationship between protein sequence and the 3D structure at equilibrium. Although intrinsically disordered proteins (IDPs) do not fold into a specific 3D structure, breaking this…

Anisotropy at the level of the inter-particle interaction provides the particles with specific instructions for the self-assembly of target structures. The ability to synthesize non-spherical colloids, together with the possibility of…

Soft Condensed Matter · Physics 2020-01-03 Carina Karner , Christoph Dellago , Emanuela Bianchi

Multi-component self-assembly mixtures offer the possibility of encoding multiple target structures with the same set of interacting components. Selective retrieval of one of the stored structures has been attempted by preparing an initial…

Soft Condensed Matter · Physics 2022-03-23 Arunkumar Bupathy , Daan Frenkel , Srikanth Sastry

Isotropic pairwise interactions that promote the self assembly of complex particle morphologies have been discovered by inverse design strategies derived from the molecular coarse-graining literature. While such approaches provide an avenue…

Statistical Mechanics · Physics 2019-10-15 Beth A. Lindquist , Ryan B. Jadrich , Michael P. Howard , Thomas M. Truskett

We study the self-assembly behaviour of patchy particles with `protein-like' interactions that can be considered as a minimal model for the assembly of viral capsids and other shell-like protein complexes. We thoroughly explore the…

Soft Condensed Matter · Physics 2010-01-21 Alex W. Wilber , Jonathan P. K. Doye , Ard A. Louis , Anna C. F. Lewis

In order to avoid disadvantages of monocropping for soil and environment, it is advisable to practice intercropping of various plant species whenever possible. However, intercropping is challenging as it requires a balanced planting…

Computers and Society · Computer Science 2021-12-21 Maurice Günder , Nico Piatkowski , Laura von Rueden , Rafet Sifa , Christian Bauckhage

One emerging approach for the fabrication of complex architectures on the nanoscale is to utilize particles customized to intrinsically self-assemble into a desired structure. Inverse methods of statistical mechanics have proven…

Materials Science · Physics 2017-09-08 R. B. Jadrich , B. A. Lindquist , T. M. Truskett

Inverse design can be a useful strategy for discovering interactions that drive particles to spontaneously self-assemble into a desired structure. Here, we extend an inverse design methodology--relative entropy optimization--to determine…

Soft Condensed Matter · Physics 2018-03-16 William D. Piñeros , Beth A. Lindquist , Ryan B. Jadrich , Thomas M. Truskett

Contact unit size reduction is a widely studied mechanism as a means to improve adhesion in natural fibrillar systems, such as those observed in beetles or geckos. However, these animals also display complex structural features in the way…

Soft Condensed Matter · Physics 2018-06-22 Lucas Brely , Federico Bosia , Nicola M. Pugno

Hierarchical granular piles composed of aggregates are key structural features in both geoscience and planetary science, from fault gouge in seismic zones to the internal structures of comets. Although experimental studies have suggested a…

Soft Condensed Matter · Physics 2025-06-26 Sota Arakawa , Mikito Furuichi , Daisuke Nishiura