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Knowledge Graphs (KG) and associated Knowledge Graph Embedding (KGE) models have recently begun to be explored in the context of drug discovery and have the potential to assist in key challenges such as target identification. In the drug…

Biomolecules · Quantitative Biology 2022-06-01 Stephen Bonner , Ian P Barrett , Cheng Ye , Rowan Swiers , Ola Engkvist , Charles Tapley Hoyt , William L Hamilton

Knowledge graph embedding (KGE) focuses on representing the entities and relations of a knowledge graph (KG) into the continuous vector spaces, which can be employed to predict the missing triples to achieve knowledge graph completion…

Computation and Language · Computer Science 2023-07-25 Yichi Zhang , Wen Zhang

Despite the remarkable success of deep neural networks (DNNs) in computer vision, they fail to remain high-performing when facing distribution shifts between training and testing data. In this paper, we propose Knowledge-Guided Visual…

Computer Vision and Pattern Recognition · Computer Science 2025-02-13 Hongkuan Zhou , Lavdim Halilaj , Sebastian Monka , Stefan Schmid , Yuqicheng Zhu , Bo Xiong , Steffen Staab

Knowledge graphs (KGs) have proven to be effective for high-quality recommendation, where the connectivities between users and items provide rich and complementary information to user-item interactions. Most existing methods, however, are…

Information Retrieval · Computer Science 2021-09-16 Xiao Sha , Zhu Sun , Jie Zhang

Knowledge Graphs (KGs) are widely employed in artificial intelligence applications, such as question-answering and recommendation systems. However, KGs are frequently found to be incomplete. While much of the existing literature focuses on…

Artificial Intelligence · Computer Science 2024-06-28 Sakher Khalil Alqaaidi , Krzysztof Kochut

Many mathematical models have been leveraged to design embeddings for representing Knowledge Graph (KG) entities and relations for link prediction and many downstream tasks. These mathematically-inspired models are not only highly scalable…

Artificial Intelligence · Computer Science 2023-09-25 Xiou Ge , Yun-Cheng Wang , Bin Wang , C. -C. Jay Kuo

Thanks to the increasing availability of drug-drug interactions (DDI) datasets and large biomedical knowledge graphs (KGs), accurate detection of adverse DDI using machine learning models becomes possible. However, it remains largely an…

Machine Learning · Computer Science 2021-05-10 Yue Yu , Kexin Huang , Chao Zhang , Lucas M. Glass , Jimeng Sun , Cao Xiao

Knowledge graph embedding (KGE) models encode the structural information of knowledge graphs to predicting new links. Effective training of these models requires distinguishing between positive and negative samples with high precision.…

Machine Learning · Computer Science 2025-04-07 Makoto Takamoto , Daniel Oñoro-Rubio , Wiem Ben Rim , Takashi Maruyama , Bhushan Kotnis

Knowledge graph is a popular format for representing knowledge, with many applications to semantic search engines, question-answering systems, and recommender systems. Real-world knowledge graphs are usually incomplete, so knowledge graph…

Machine Learning · Computer Science 2023-04-26 Hung Nghiep Tran , Atsuhiro Takasu

Knowledge graphs (KGs) consist of links that describe relationships between entities. Due to the difficulty of manually enumerating all relationships between entities, automatically completing them is essential for KGs. Knowledge Graph…

Computation and Language · Computer Science 2024-06-07 Yusuke Sakai , Hidetaka Kamigaito , Katsuhiko Hayashi , Taro Watanabe

Recent years have seen a rapid growth of utilizing graph neural networks (GNNs) in the biomedical domain for tackling drug-related problems. However, like any other deep architectures, GNNs are data hungry. While requiring labels in real…

Biological Physics · Physics 2022-05-03 Mengying Sun , Jing Xing , Huijun Wang , Bin Chen , Jiayu Zhou

Complex node interactions are common in knowledge graphs, and these interactions also contain rich knowledge information. However, traditional methods usually treat a triple as a training unit during the knowledge representation learning…

Computation and Language · Computer Science 2021-10-01 Bin He , Di Zhou , Jinghui Xiao , Xin jiang , Qun Liu , Nicholas Jing Yuan , Tong Xu

A large-scale knowledge graph enhances reproducibility in biomedical data discovery by providing a standardized, integrated framework that ensures consistent interpretation across diverse datasets. It improves generalizability by connecting…

Methodology · Statistics 2024-10-11 Suqi Liu , Tianxi Cai , Xiaoou Li

Multi-scale biomedical knowledge networks are expanding with emerging experimental technologies that generates multi-scale biomedical big data. Link prediction is increasingly used especially in bipartite biomedical networks to identify…

Social and Information Networks · Computer Science 2022-02-25 Jinjiang Guo , Jie Li , Dawei Leng , Lurong Pan

Knowledge graphs have emerged as an important model for studying complex multi-relational data. This has given rise to the construction of numerous large scale but incomplete knowledge graphs encoding information extracted from various…

Machine Learning · Computer Science 2018-07-24 Rakshit Trivedi , Bunyamin Sisman , Jun Ma , Christos Faloutsos , Hongyuan Zha , Xin Luna Dong

Knowledge graph embedding~(KGE) aims to represent entities and relations into low-dimensional vectors for many real-world applications. The representations of entities and relations are learned via contrasting the positive and negative…

Artificial Intelligence · Computer Science 2022-02-22 Feihu Che , Guohua Yang , Pengpeng Shao , Dawei Zhang , Jianhua Tao

A large number of studies have emerged for Multimodal Knowledge Graph Completion (MKGC) to predict the missing links in MKGs. However, fewer studies have been proposed to study the inductive MKGC (IMKGC) involving emerging entities unseen…

Multimedia · Computer Science 2024-07-04 Yu Zhao , Ying Zhang , Baohang Zhou , Xinying Qian , Kehui Song , Xiangrui Cai

Drug-drug interaction prediction is a crucial issue in molecular biology. Traditional methods of observing drug-drug interactions through medical experiments require significant resources and labor. This paper presents a medical knowledge…

Computation and Language · Computer Science 2024-07-29 Peng Gao , Feng Gao , Jian-Cheng Ni , Yu Wang , Fei Wang

Incorporating factual knowledge into pre-trained language models (PLM) such as BERT is an emerging trend in recent NLP studies. However, most of the existing methods combine the external knowledge integration module with a modified…

Computation and Language · Computer Science 2022-05-06 Yinquan Lu , Haonan Lu , Guirong Fu , Qun Liu

Automatic surgical gesture recognition is fundamentally important to enable intelligent cognitive assistance in robotic surgery. With recent advancement in robot-assisted minimally invasive surgery, rich information including surgical…

Computer Vision and Pattern Recognition · Computer Science 2021-06-30 Yonghao Long , Jie Ying Wu , Bo Lu , Yueming Jin , Mathias Unberath , Yun-Hui Liu , Pheng Ann Heng , Qi Dou