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Prototyping plays a critical role in the development of machine learning (ML) solutions, yet existing tools often provide limited support for effective collaboration and knowledge reuse among stakeholders. This paper introduces Proto-ML, an…

Software Engineering · Computer Science 2026-02-26 Selin Coban , Miguel Perez , Horst Lichter

Learned optimizers have been an active research topic over the past decade, with increasing progress toward practical, general-purpose optimizers that can serve as drop-in replacements for widely used methods like Adam. However, recent…

Machine Learning · Computer Science 2026-04-20 Paul Janson , Benjamin Therien , Quentin Anthony , Xiaolong Huang , Abhinav Moudgil , Eugene Belilovsky

We introduce PathBench-MIL, an open-source AutoML and benchmarking framework for multiple instance learning (MIL) in histopathology. The system automates end-to-end MIL pipeline construction, including preprocessing, feature extraction, and…

Computer Vision and Pattern Recognition · Computer Science 2025-12-22 Siemen Brussee , Pieter A. Valkema , Jurre A. J. Weijer , Thom Doeleman , Anne M. R. Schrader , Jesper Kers

Online data streams make training machine learning models hard because of distribution shift and new patterns emerging over time. For natural language processing (NLP) tasks that utilize a collection of features based on lexicons and rules,…

Computation and Language · Computer Science 2022-11-28 Shubhanshu Mishra , Jana Diesner

This report presents the Prime Collective Communications Library (PCCL), a novel fault-tolerant collective communication library designed for distributed ML workloads over the public internet. PCCL introduces a new programming model that…

Distributed, Parallel, and Cluster Computing · Computer Science 2025-05-21 Michael Keiblinger , Mario Sieg , Jack Min Ong , Sami Jaghouar , Johannes Hagemann

We present PyLRO, an open-source Python calculator designed to detect, quantify, and display long-range order in periodic structures. The program's design methodology, workflow, and approach to order quantification are described and…

Materials Science · Physics 2025-06-06 Kevin Parrish , Qingyang Hu , Qiang Zhu

Process malleability has proved to have a highly positive impact on the resource utilization and global productivity in data centers compared with the conventional static resource allocation policy. However, the non-negligible additional…

Distributed, Parallel, and Cluster Computing · Computer Science 2026-04-30 Sergio Iserte , Rafael Mayo , Enrique S. Quintana-Ortí , Antonio J. Peña

The pyLOT library offers a Python implementation of linearized optimal transport (LOT) techniques and methods to use in downstream tasks. The pipeline embeds probability distributions into a Hilbert space via the Optimal Transport maps from…

Machine Learning · Statistics 2025-02-06 Jun Linwu , Varun Khurana , Nicholas Karris , Alexander Cloninger

By exploiting the correlation between the structure and the solution of Mixed-Integer Linear Programming (MILP), Machine Learning (ML) has become a promising method for solving large-scale MILP problems. Existing ML-based MILP solvers…

Machine Learning · Computer Science 2025-01-03 Yixuan Li , Can Chen , Jiajun Li , Jiahui Duan , Xiongwei Han , Tao Zhong , Vincent Chau , Weiwei Wu , Wanyuan Wang

Background: The study of genome-scale metabolic models and their underlying networks is one of the most important fields in systems biology. The complexity of these models and their description makes the use of computational tools an…

Molecular Networks · Quantitative Biology 2012-12-03 D. Gamermann , A. Montagud , R. A. Jaime Infante , J. Triana , P. F. de Córdoba , J. F. Urchueguía

Artificial Intelligence models encoding biology and chemistry are opening new routes to high-throughput and high-quality in-silico drug development. However, their training increasingly relies on computational scale, with recent protein…

Machine Learning · Computer Science 2025-09-10 Peter St. John , Dejun Lin , Polina Binder , Malcolm Greaves , Vega Shah , John St. John , Adrian Lange , Patrick Hsu , Rajesh Illango , Arvind Ramanathan , Anima Anandkumar , David H Brookes , Akosua Busia , Abhishaike Mahajan , Stephen Malina , Neha Prasad , Sam Sinai , Lindsay Edwards , Thomas Gaudelet , Cristian Regep , Martin Steinegger , Burkhard Rost , Alexander Brace , Kyle Hippe , Luca Naef , Keisuke Kamata , George Armstrong , Kevin Boyd , Zhonglin Cao , Han-Yi Chou , Simon Chu , Allan dos Santos Costa , Sajad Darabi , Eric Dawson , Kieran Didi , Cong Fu , Mario Geiger , Michelle Gill , Darren J Hsu , Gagan Kaushik , Maria Korshunova , Steven Kothen-Hill , Youhan Lee , Meng Liu , Micha Livne , Zachary McClure , Jonathan Mitchell , Alireza Moradzadeh , Ohad Mosafi , Youssef Nashed , Saee Paliwal , Yuxing Peng , Sara Rabhi , Farhad Ramezanghorbani , Danny Reidenbach , Camir Ricketts , Brian C Roland , Kushal Shah , Tyler Shimko , Hassan Sirelkhatim , Savitha Srinivasan , Abraham C Stern , Dorota Toczydlowska , Srimukh Prasad Veccham , Niccolò Alberto Elia Venanzi , Anton Vorontsov , Jared Wilber , Isabel Wilkinson , Wei Jing Wong , Eva Xue , Cory Ye , Xin Yu , Yang Zhang , Guoqing Zhou , Becca Zandstein , Alejandro Chacon , Prashant Sohani , Maximilian Stadler , Christian Hundt , Feiwen Zhu , Christian Dallago , Bruno Trentini , Emine Kucukbenli , Saee Paliwal , Timur Rvachov , Eddie Calleja , Johnny Israeli , Harry Clifford , Risto Haukioja , Nicholas Haemel , Kyle Tretina , Neha Tadimeti , Anthony B Costa

Machine learning (ML) in high-energy physics (HEP) has moved in the LHC era from an internal detail of experiment software, to an unavoidable public component of many physics data analyses. Scientific reproducibility thus requires that it…

High Energy Physics - Phenomenology · Physics 2026-05-28 Andy Buckley , Louie Corpe , Martin Habedank , Tomasz Procter

We present the Python-based Molecule Builder for ESPResSo (pyMBE), an open source software to design custom Coarse-Grained (CG) models, as well as pre-defined models of polyelectrolytes, peptides and globular proteins in the Extensible…

In this paper, we present madmom, an open-source audio processing and music information retrieval (MIR) library written in Python. madmom features a concise, NumPy-compatible, object oriented design with simple calling conventions and…

Sound · Computer Science 2016-05-25 Sebastian Böck , Filip Korzeniowski , Jan Schlüter , Florian Krebs , Gerhard Widmer

The deep learning language of choice these days is Python; measured by factors such as available libraries and technical support, it is hard to beat. At the same time, software written in lower-level programming languages like C++ retain…

Computation and Language · Computer Science 2024-08-23 Thamme Gowda , Roman Grundkiewicz , Elijah Rippeth , Matt Post , Marcin Junczys-Dowmunt

This paper describes a deep-SDM framework, MALPOLON. Written in Python and built upon the PyTorch library, this framework aims to facilitate training and inferences of deep species distribution models (deep-SDM) and sharing for users with…

Machine Learning · Computer Science 2024-09-27 Theo Larcher , Lukas Picek , Benjamin Deneu , Titouan Lorieul , Maximilien Servajean , Alexis Joly

Procedural Knowledge Libraries (PKLs) are frameworks for capturing the full arc of scientific inquiry, not just its outcomes. Whereas traditional libraries store static end products, PKLs preserve the process that leads to those results,…

Digital Libraries · Computer Science 2025-06-18 Hamidah Oderinwale

Library migration is the process of replacing a library with a similar one in a software project. Manual library migration is time consuming and error prone, as it requires developers to understand the Application Programming Interfaces…

Software Engineering · Computer Science 2026-02-25 Mohayeminul Islam , Ajay Kumar Jha , May Mahmoud , Sarah Nadi

sQUlearn introduces a user-friendly, NISQ-ready Python library for quantum machine learning (QML), designed for seamless integration with classical machine learning tools like scikit-learn. The library's dual-layer architecture serves both…

relentless is an open-source Python package that enables the optimization of objective functions computed using molecular dynamics simulations. It has a high-level, extensible interface for model parametrization; setting up, running, and…

Soft Condensed Matter · Physics 2024-08-07 Adithya N Sreenivasan , C. Levi Petix , Zachary M. Sherman , Michael P. Howard