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We present a weakly supervised deep learning method to perform instance segmentation of cells present in microscopy images. Annotation of biomedical images in the lab can be scarce, incomplete, and inaccurate. This is of concern when…

Computer Vision and Pattern Recognition · Computer Science 2019-08-28 Fidel A. Guerrero-Peña , Pedro D. Marrero Fernandez , Tsang Ing Ren , Alexandre Cunha

Nuclei instance segmentation on histopathology images is of great clinical value for disease analysis. Generally, fully-supervised algorithms for this task require pixel-wise manual annotations, which is especially time-consuming and…

Computer Vision and Pattern Recognition · Computer Science 2023-06-06 Yang Zhou , Yongjian Wu , Zihua Wang , Bingzheng Wei , Maode Lai , Jianzhong Shou , Yubo Fan , Yan Xu

In the last few years, deep learning classifiers have shown promising results in image-based medical diagnosis. However, interpreting the outputs of these models remains a challenge. In cancer diagnosis, interpretability can be achieved by…

Computer Vision and Pattern Recognition · Computer Science 2021-06-16 Kangning Liu , Yiqiu Shen , Nan Wu , Jakub Chłędowski , Carlos Fernandez-Granda , Krzysztof J. Geras

Training a Convolutional Neural Network (CNN) for semantic segmentation typically requires to collect a large amount of accurate pixel-level annotations, a hard and expensive task. In contrast, simple image tags are easier to gather. With…

Computer Vision and Pattern Recognition · Computer Science 2019-02-25 Carolina Redondo-Cabrera , Marcos Baptista-Ríos , Roberto J. López-Sastre

From the simple measurement of tissue attributes in pathology workflow to designing an explainable diagnostic/prognostic AI tool, access to accurate semantic segmentation of tissue regions in histology images is a prerequisite. However,…

Image and Video Processing · Electrical Eng. & Systems 2021-08-31 Mostafa Jahanifar , Neda Zamani Tajeddin , Navid Alemi Koohbanani , Nasir Rajpoot

Audio-visual segmentation is a challenging task that aims to predict pixel-level masks for sound sources in a video. Previous work applied a comprehensive manually designed architecture with countless pixel-wise accurate masks as…

Computer Vision and Pattern Recognition · Computer Science 2023-11-28 Shentong Mo , Bhiksha Raj

Semi-supervised segmentation remains challenging in medical imaging since the amount of annotated medical data is often scarce and there are many blurred pixels near the adhesive edges or in the low-contrast regions. To address the issues,…

Image and Video Processing · Electrical Eng. & Systems 2022-06-29 Yicheng Wu , Zhonghua Wu , Qianyi Wu , Zongyuan Ge , Jianfei Cai

Most existing weakly supervised semantic segmentation (WSSS) methods rely on Class Activation Mapping (CAM) to extract coarse class-specific localization maps using image-level labels. Prior works have commonly used an off-line heuristic…

Computer Vision and Pattern Recognition · Computer Science 2024-03-05 Lian Xu , Mohammed Bennamoun , Farid Boussaid , Wanli Ouyang , Ferdous Sohel , Dan Xu

Weakly-Supervised Semantic Segmentation (WSSS) aims to train segmentation models using image data with only image-level supervision. Since precise pixel-level annotations are not accessible, existing methods typically focus on producing…

Computer Vision and Pattern Recognition · Computer Science 2025-01-14 Ci-Siang Lin , Chien-Yi Wang , Yu-Chiang Frank Wang , Min-Hung Chen

Histopathological image analysis is an essential process for the discovery of diseases such as cancer. However, it is challenging to train CNN on whole slide images (WSIs) of gigapixel resolution considering the available memory capacity.…

Image and Video Processing · Electrical Eng. & Systems 2019-10-11 Shusuke Takahama , Yusuke Kurose , Yusuke Mukuta , Hiroyuki Abe , Masashi Fukayama , Akihiko Yoshizawa , Masanobu Kitagawa , Tatsuya Harada

Noisy labels, inevitably existing in pseudo segmentation labels generated from weak object-level annotations, severely hampers model optimization for semantic segmentation. Previous works often rely on massive hand-crafted losses and…

Computer Vision and Pattern Recognition · Computer Science 2024-01-23 Shenwang Jiang , Jianan Li , Ying Wang , Wenxuan Wu , Jizhou Zhang , Bo Huang , Tingfa Xu

We propose SAMed, a general solution for medical image segmentation. Different from the previous methods, SAMed is built upon the large-scale image segmentation model, Segment Anything Model (SAM), to explore the new research paradigm of…

Computer Vision and Pattern Recognition · Computer Science 2023-10-18 Kaidong Zhang , Dong Liu

Histopathology image analysis plays a crucial role in cancer diagnosis. However, training a clinically applicable segmentation algorithm requires pathologists to engage in labour-intensive labelling. In contrast, weakly supervised learning…

Computer Vision and Pattern Recognition · Computer Science 2024-05-28 Gang Xu , Shuhao Wang , Lingyu Zhao , Xiao Chen , Tongwei Wang , Lang Wang , Zhenwei Luo , Dahan Wang , Zewen Zhang , Aijun Liu , Wei Ba , Zhigang Song , Huaiyin Shi , Dingrong Zhong , Jianpeng Ma

Compared to conventional semantic segmentation with pixel-level supervision, Weakly Supervised Semantic Segmentation (WSSS) with image-level labels poses the challenge that it always focuses on the most discriminative regions, resulting in…

Computer Vision and Pattern Recognition · Computer Science 2023-12-19 Jingxuan He , Lechao Cheng , Chaowei Fang , Zunlei Feng , Tingting Mu , Mingli Song

Semi-supervised learning has gained considerable popularity in medical image segmentation tasks due to its capability to reduce reliance on expert-examined annotations. Several mean-teacher (MT) based semi-supervised methods utilize…

Computer Vision and Pattern Recognition · Computer Science 2025-08-13 Kaiwen Huang , Tao Zhou , Huazhu Fu , Yizhe Zhang , Yi Zhou , Xiao-Jun Wu

Poor performance of quantitative analysis in histopathological Whole Slide Images (WSI) has been a significant obstacle in clinical practice. Annotating large-scale WSIs manually is a demanding and time-consuming task, unlikely to yield the…

Computer Vision and Pattern Recognition · Computer Science 2023-08-08 Sarah Cechnicka , James Ball , Hadrien Reynaud , Callum Arthurs , Candice Roufosse , Bernhard Kainz

Weakly supervised semantic segmentation (WSSS) with image-level labels is a challenging task. Mainstream approaches follow a multi-stage framework and suffer from high training costs. In this paper, we explore the potential of Contrastive…

Computer Vision and Pattern Recognition · Computer Science 2023-03-24 Yuqi Lin , Minghao Chen , Wenxiao Wang , Boxi Wu , Ke Li , Binbin Lin , Haifeng Liu , Xiaofei He

In surgical procedures, correct instrument counting is essential. Instance segmentation is a location method that locates not only an object's bounding box but also each pixel's specific details. However, obtaining mask-level annotations is…

Computer Vision and Pattern Recognition · Computer Science 2023-11-17 Zhen Sun , Huan Xu , Jinlin Wu , Zhen Chen , Zhen Lei , Hongbin Liu

Medical image segmentation remains challenging due to limited annotations for training, ambiguous anatomical features, and domain shifts. While vision-language models such as CLIP offer strong cross-modal representations, their potential…

Computer Vision and Pattern Recognition · Computer Science 2026-02-25 Taha Koleilat , Hojat Asgariandehkordi , Omid Nejati Manzari , Berardino Barile , Yiming Xiao , Hassan Rivaz

Semantic segmentation, like other fields of computer vision, has seen a remarkable performance advance by the use of deep convolution neural networks. However, considering that neighboring pixels are heavily dependent on each other, both…

Computer Vision and Pattern Recognition · Computer Science 2017-08-08 Hyojin Park , Jisoo Jeong , Youngjoon Yoo , Nojun Kwak