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The complexity of neural dynamics stems in part from the complexity of the underlying anatomy. Yet how the organization of white matter architecture constrains how the brain transitions from one cognitive state to another remains unknown.…

Neurons and Cognition · Quantitative Biology 2017-01-11 Shi Gu , Richard F. Betzel , Matthew Cieslak , Philip R. Delio , Scott T. Grafton , Fabio Pasqualetti , Danielle S. Bassett

In recent years, the rapid development of neuroimaging technology has been providing many powerful tools for cognitive neuroscience research. Among them, the functional magnetic resonance imaging (fMRI), which has high spatial resolution,…

Human-Computer Interaction · Computer Science 2018-08-20 Yang Wang , Dongrui Wu

Functional MRI (fMRI) has become the most common method for investigating the human brain. However, fMRI data present some complications for statistical analysis and modeling. One recently developed approach to these data focuses on…

Applications · Statistics 2015-03-19 Vincent Q. Vu , Pradeep Ravikumar , Thomas Naselaris , Kendrick N. Kay , Jack L. Gallant , Bin Yu

Functional magnetic resonance imaging (fMRI) is a powerful tool for probing brain function, yet reliable clinical diagnosis is hampered by low signal-to-noise ratios, inter-subject variability, and the limited frequency awareness of…

Computer Vision and Pattern Recognition · Computer Science 2026-03-03 Junhao Jia , Yifei Sun , Yunyou Liu , Cheng Yang , Changmiao Wang , Feiwei Qin , Yong Peng , Wenwen Min

Decoding visual stimuli from neural responses recorded by functional Magnetic Resonance Imaging (fMRI) presents an intriguing intersection between cognitive neuroscience and machine learning, promising advancements in understanding human…

Computer Vision and Pattern Recognition · Computer Science 2023-12-29 Jingyuan Sun , Mingxiao Li , Zijiao Chen , Yunhao Zhang , Shaonan Wang , Marie-Francine Moens

Machine Learning (ML) is increasingly being used for computer aided diagnosis of brain related disorders based on structural magnetic resonance imaging (MRI) data. Most of such work employs biologically and medically meaningful hand-crafted…

Machine Learning · Computer Science 2018-05-04 Ayush Jaiswal , Dong Guo , Cauligi S. Raghavendra , Paul Thompson

Brain functional connectivity alterations, that is, pathological changes in the signal exchange between areas of the brain, occur in several neurological diseases, including neurodegenerative and neuropsychiatric ones. They consist in…

Neurons and Cognition · Quantitative Biology 2026-03-25 Maria Mannone , Patrizia Ribino , Peppino Fazio , Norbert Marwan

Understanding the dynamic reorganization of brain networks is critical for predicting cognitive decline, neurological progression, and individual variability in clinical outcomes. This work proposes a multimodal graph neural network…

Machine Learning · Computer Science 2026-02-11 Preksha Girish , Rachana Mysore , Kiran K. N. , Hiranmayee R. , Shipra Prashanth , Shrey Kumar

Recent studies in neuroscience show great potential of functional brain networks constructed from fMRI data for popularity modeling and clinical predictions. However, existing functional brain networks are noisy and unaware of downstream…

Machine Learning · Computer Science 2021-07-26 Xuan Kan , Hejie Cui , Ying Guo , Carl Yang

Discovering reliable and informative relationships among brain regions from functional magnetic resonance imaging (fMRI) signals is essential in phenotypic predictions. Most of the current methods fail to accurately characterize those…

Neurons and Cognition · Quantitative Biology 2024-06-11 Weikang Qiu , Huangrui Chu , Selena Wang , Haolan Zuo , Xiaoxiao Li , Yize Zhao , Rex Ying

Functional magnetic resonance imaging (fMRI) is a powerful tool for investigating human brain function. However, the high cost of data acquisition and the inherent subjectivity of psychiatric rating scales often lead to datasets with small…

Machine Learning · Computer Science 2026-05-29 Jiyao Wang , Peiyu Duan , Nicha C. Dvornek , Lawrence H. Staib , Denis Sukhodolsky , Pamela Ventola , James S. Duncan

Human cognition is theorized to operate in two modes: fast, intuitive System 1 thinking and slow, deliberate System 2 thinking. While current Large Reasoning Models (LRMs) excel at System 2 thinking, their inability to perform fast thinking…

Computation and Language · Computer Science 2025-10-31 Zhengkai Lin , Zhihang Fu , Ze Chen , Chao Chen , Liang Xie , Wenxiao Wang , Deng Cai , Zheng Wang , Jieping Ye

Functional magnetic resonance imaging (fMRI) has been commonly used to construct functional connectivity networks (FCNs) of the human brain. TFCNs are primarily limited to quantifying pairwise relationships between ROIs ignoring higher…

Signal Processing · Electrical Eng. & Systems 2025-07-15 Duc Vu , Selin Aviyente

Accurate diagnosis of psychiatric disorders plays a critical role in improving the quality of life for patients and potentially supports the development of new treatments. Many studies have been conducted on machine learning techniques that…

Machine Learning · Statistics 2019-04-15 Takashi Matsubara , Tetsuo Tashiro , Kuniaki Uehara

Whole-brain computational modeling based on structural connectivity has shown great promise in successfully simulating fMRI BOLD signals with temporal co-activation patterns that are highly similar to empirical functional connectivity…

Neurons and Cognition · Quantitative Biology 2019-11-14 Neda Kaboodvand , Martijn P van den Heuvel , Peter Fransson

The human brain has long inspired the pursuit of artificial intelligence (AI). Recently, neuroimaging studies provide compelling evidence of alignment between the computational representation of artificial neural networks (ANNs) and the…

Neurons and Cognition · Quantitative Biology 2024-11-01 Haiyang Sun , Lin Zhao , Zihao Wu , Xiaohui Gao , Yutao Hu , Mengfei Zuo , Wei Zhang , Junwei Han , Tianming Liu , Xintao Hu

The human brain is a complex system, and understanding its mechanisms has been a long-standing challenge in neuroscience. The study of the functional connectome, which maps the functional connections between different brain regions, has…

Neural and Evolutionary Computing · Computer Science 2025-04-14 Tananun Songdechakraiwut , Yutong Wu

Smart systems that can accurately diagnose patients with mental disorders and identify effective treatments based on brain functional imaging data are of great applicability and are gaining much attention. Most previous machine learning…

Computer Vision and Pattern Recognition · Computer Science 2017-12-05 Jumana Dakka , Pouya Bashivan , Mina Gheiratmand , Irina Rish , Shantenu Jha , Russell Greiner

Deep learning has advanced fMRI analysis, yet it remains unclear which architectural inductive biases are most effective at capturing functional patterns in human brain activity. This issue is particularly important in small-sample…

Neurons and Cognition · Quantitative Biology 2025-09-23 Behdad Khodabandehloo , Reza Rajimehr

Understanding how large-scale functional brain networks reorganize during cognitive decline remains a central challenge in neuroimaging. While recent self-supervised models have shown promise for learning representations from resting-state…

Machine Learning · Computer Science 2026-03-03 Karanpartap Singh , Adam Turnbull , Mohammad Abbasi , Kilian Pohl , Feng Vankee Lin , Ehsan Adeli