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Large Language Models (LLMs) show promise in biomedicine but lack true causal understanding, relying instead on correlations. This paper envisions causal LLM agents that integrate multimodal data (text, images, genomics, etc.) and perform…

Microwell microfluidics has been utilized for single-cell analysis to reveal heterogeneity in gene expression, signaling pathways, and phenotypic responses for identifying rare cell types, understanding disease progression, and developing…

In recent years, the integration of large language models (LLMs) has revolutionized the field of robotics, enabling robots to communicate, understand, and reason with human-like proficiency. This paper explores the multifaceted impact of…

Large language models (LLMs) have achieved remarkable progress in the field of natural language processing (NLP), demonstrating remarkable abilities in producing text that resembles human language for various tasks. This opens up new…

Large language models have proven themselves highly flexible, able to solve a wide range of generative tasks, such as abstractive summarization and open-ended question answering. In this paper we extend the capabilities of LLMs by directly…

Large Language Models (LLMs) excel at capturing latent semantics and contextual relationships across diverse modalities. However, in modeling user behavior from sequential interaction data, performance often suffers when such semantic…

Speech Large Language Models (Speech LLMs) have emerged as a crucial paradigm in recent years, extending the capabilities of traditional LLMs to speech tasks such as automatic speech recognition (ASR) and spoken dialogue modeling. However,…

The applications of large language models (LLMs) are promising for biomedical and healthcare research. Despite the availability of open-source LLMs trained using a wide range of biomedical data, current research on the applications of LLMs…

This paper investigates the utilization of Large Language Models (LLMs) for solving complex linguistic puzzles, a domain requiring advanced reasoning and adept translation capabilities akin to human cognitive processes. We explore specific…

Large Language Models (LLMs) have revolutionized various sectors, including healthcare where they are employed in diverse applications. Their utility is particularly significant in the context of rare diseases, where data scarcity,…

Large Language Models (LLMs) have demonstrated remarkable efficacy in text embedding, yet current adaptation methods like LoRA face significant bottlenecks in computational efficiency and cross-architecture transferability. Whenever a new…

Large Language Models (LLMs) have achieved significant progress across various fields and have exhibited strong potential in evolutionary computation, such as generating new solutions and automating algorithm design. Surrogate-assisted…

As Large Language Models (LLMs) rapidly evolve, their influence in science is becoming increasingly prominent. The emerging capabilities of LLMs in task generalization and free-form dialogue can significantly advance fields like chemistry…

Designing proteins de novo with tailored structural, physicochemical, and functional properties remains a grand challenge in biotechnology, medicine, and materials science, due to the vastness of sequence space and the complex coupling…

Large decoder-only language models (LLMs) have achieved remarkable success in generation and reasoning tasks, where they generate text responses given instructions. However, many applications, e.g., retrieval augmented generation (RAG),…

Large models have demonstrated significant progress across various domains, particularly in tasks related to text generation. In the domain of Table to Text, many Large Language Model (LLM)-based methods currently resort to modifying…

Large language models (LLMs) often struggle with complex mathematical tasks, prone to "hallucinating" incorrect answers due to their reliance on statistical patterns. This limitation is further amplified in average Small LangSLMs with…

There are already many DNA large language models, but most of them still follow traditional uses, such as extracting sequence features for classification tasks. More innovative applications of large language models, such as prompt…

Multi-objective optimization is a common problem in practical applications, and multi-objective evolutionary algorithm (MOEA) is considered as one of the effective methods to solve these problems. However, their randomness sometimes…

We present a modular framework powered by large language models (LLMs) that automates and streamlines key tasks across the early-stage computational drug discovery pipeline. By combining LLM reasoning with domain-specific tools, the…