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Large language models (LLMs) have demonstrated broad utility across molecular domains, spanning drug discovery and materials design. Analyzing LLMs' latent representations is crucial for elucidating their underlying mechanisms, improving…

Machine Learning · Computer Science 2026-02-03 Zhuoran Li , Xu Sun , Wanyu Lin , Jiannong Cao

Translating single-cell RNA sequencing (scRNA-seq) data into mechanistic biological hypotheses remains a critical bottleneck, as agentic AI systems lack direct access to transcriptomic representations while expression foundation models…

Genomics · Quantitative Biology 2026-03-18 Omar Coser

Large language models (LLMs) have demonstrated remarkable capabilities across various domains, yet their application to relational deep learning (RDL) remains underexplored. Existing approaches adapt LLMs by traversing relational links…

Computation and Language · Computer Science 2025-06-09 Fang Wu , Vijay Prakash Dwivedi , Jure Leskovec

Single-cell RNA sequencing (scRNA-seq) provides unprecedented insights into cellular heterogeneity, enabling detailed analysis of complex biological systems at single-cell resolution. However, the high dimensionality and technical noise…

Genomics · Quantitative Biology 2025-09-04 Hojjat Torabi Goudarzi , Maziyar Baran Pouyan

Ontology matching (OM) plays an essential role in enabling semantic interoperability and integration across heterogeneous knowledge sources, particularly in the biomedical domain which contains numerous complex concepts related to diseases…

Artificial Intelligence · Computer Science 2026-04-03 Yiping Song , Jiaoyan Chen , Renate A. Schmidt

We introduce the framework of "social learning" in the context of large language models (LLMs), whereby models share knowledge with each other in a privacy-aware manner using natural language. We present and evaluate two approaches for…

Machine Learning · Computer Science 2024-02-09 Amirkeivan Mohtashami , Florian Hartmann , Sian Gooding , Lukas Zilka , Matt Sharifi , Blaise Aguera y Arcas

Large Language Models (LLMs) excel at extracting common patterns from large-scale corpora, yet they struggle with rare, low-resource, or previously unseen scenarios-such as niche hardware deployment issues or irregular IoT device…

Computation and Language · Computer Science 2025-12-23 Hong Su

Pre-trained large language models (LLMs) exhibit powerful capabilities for generating natural text. Evolutionary algorithms (EAs) can discover diverse solutions to complex real-world problems. Motivated by the common collective and…

Neural and Evolutionary Computing · Computer Science 2025-03-10 Chao Wang , Jiaxuan Zhao , Licheng Jiao , Lingling Li , Fang Liu , Shuyuan Yang

Large Language Models (LLMs) have shown significant potential for ontology engineering. However, it is still unclear to what extent they are applicable to the task of domain-specific ontology generation. In this study, we explore the…

Large language models (LLMs) have shown impressive promise in code generation, yet their progress remains limited by the shortage of large-scale datasets that are both diverse and well-aligned with human reasoning. Most existing resources…

Machine Learning · Computer Science 2025-10-28 Amal Abed , Ivan Lukic , Jörg K. H. Franke , Frank Hutter

Large Language Models (LLMs) have exhibited exceptional performance across a spectrum of natural language processing tasks. However, their substantial sizes pose considerable challenges, particularly in computational demands and inference…

Computation and Language · Computer Science 2025-06-03 Guoxuan Chen , Han Shi , Jiawei Li , Yihang Gao , Xiaozhe Ren , Yimeng Chen , Xin Jiang , Zhenguo Li , Weiyang Liu , Chao Huang

Log data provides crucial insights for tasks like monitoring, root cause analysis, and anomaly detection. Due to the vast volume of logs, automated log parsing is essential to transform semi-structured log messages into structured…

Machine Learning · Computer Science 2025-05-16 Viktor Beck , Max Landauer , Markus Wurzenberger , Florian Skopik , Andreas Rauber

In recent years, multimodal large language models (MLLMs) have shown remarkable capabilities in tasks like visual question answering and common sense reasoning, while visual perception models have made significant strides in perception…

Computer Vision and Pattern Recognition · Computer Science 2024-06-25 Guanqun Wang , Xinyu Wei , Jiaming Liu , Ray Zhang , Yichi Zhang , Kevin Zhang , Maurice Chong , Shanghang Zhang

Understanding the latent space geometry of large language models (LLMs) is key to interpreting their behavior and improving alignment. Yet it remains unclear to what extent LLMs linearly organize representations related to semantic…

Computation and Language · Computer Science 2026-01-22 Baturay Saglam , Paul Kassianik , Blaine Nelson , Sajana Weerawardhena , Yaron Singer , Amin Karbasi

The rapid integration of Large Language Models (LLMs) into software engineering practice is reshaping how software testing activities are performed. LLMs are increasingly used to support software testing. Consequently, software testing…

Software Engineering · Computer Science 2026-03-30 Peng Yang , Yunfeng Zhu , Chao Chang , Shengcheng Yu , Zhenyu Chen , Yong Tang

There is vivid research on adapting Large Language Models (LLMs) to perform a variety of tasks in high-stakes domains such as healthcare. Despite their popularity, there is a lack of understanding of the extent and contributing factors that…

Computation and Language · Computer Science 2024-06-07 Anand Subramanian , Viktor Schlegel , Abhinav Ramesh Kashyap , Thanh-Tung Nguyen , Vijay Prakash Dwivedi , Stefan Winkler

Human bilinguals often use similar brain regions to process multiple languages, depending on when they learned their second language and their proficiency. In large language models (LLMs), how are multiple languages learned and encoded? In…

Computation and Language · Computer Science 2025-05-26 Jannik Brinkmann , Chris Wendler , Christian Bartelt , Aaron Mueller

Recent advancements in Large Multimodal Models (LMMs) have attracted interest in their generalization capability with only a few samples in the prompt. This progress is particularly relevant to the medical domain, where the quality and…

Computation and Language · Computer Science 2024-05-06 Seonhee Cho , Choonghan Kim , Jiho Lee , Chetan Chilkunda , Sujin Choi , Joo Heung Yoon

Large language models (LLMs) have been a disruptive innovation in recent years, and they play a crucial role in our daily lives due to their ability to understand and generate human-like text. Their capabilities include natural language…

Distributed, Parallel, and Cluster Computing · Computer Science 2024-10-17 Akrit Mudvari , Yuang Jiang , Leandros Tassiulas

The development of large language models (LLMs) has successfully transformed knowledge-based systems such as open domain question nswering, which can automatically produce vast amounts of seemingly coherent information. Yet, those models…

Artificial Intelligence · Computer Science 2026-01-28 Eduardo C. Garrido-Merchán , Cristina Puente
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