Related papers: A Fluid-Structure Interaction Model of the Zebrafi…
Image-based modeling is essential for understanding cardiovascular hemodynamics and advancing the diagnosis and treatment of cardiovascular diseases. Constructing patient-specific vascular models remains labor-intensive, error-prone, and…
The heart is the central part of the cardiovascular network. Its role is to pump blood to various body organs. Many cardiovascular diseases occur due to an abnormal functioning of the heart. A diseased heart leads to severe complications…
The study of the underlying physics of soft flowing materials depends heavily on numerical simulations, due to the complex structure of the governing equations reflecting the competition of concurrent mechanisms acting at widely disparate…
Infarction- or ischaemia-induced cardiac fibrosis can be arrythmogenic. We use mathematcal models for diffuse fibrosis ($\mathcal{DF}$), interstitial fibrosis ($\mathcal{IF}$), patchy fibrosis ($\mathcal{PF}$), and compact fibrosis…
A wave-ice interaction model for the marginal ice zone (MIZ) is reported, which involves both the attenuation of ocean surface waves by sea ice and the concomitant breaking of the ice by waves. It is specifically designed to embed wave-ice…
In embryonic development, programmed cell shape changes are essential for building functional organs, but in many cases the mechanisms that precisely regulate these changes remain unknown. We propose that fluid-like drag forces generated by…
We perform a stability analysis for a fluid-structure interaction problem in which a spherical elastic shell or membrane is immersed in a 3D viscous, incompressible fluid. The shell is an idealised structure having zero thickness, and has…
We extend the concept of optical flow to a dynamic non-Euclidean setting. Optical flow is traditionally computed from a sequence of flat images. It is the purpose of this paper to introduce variational motion estimation for images that are…
As the heart beats, it creates fluctuation in blood pressure leading to a pulse wave that propagates by displacing the arterial wall. These waves travel through the arterial tree and carry information about the medium that they propagate…
Zebrafish is an excellent model organism, which has been widely used in the fields of biological experiments, drug screening, and swarm intelligence. In recent years, there are a large number of techniques for tracking of zebrafish involved…
In this paper, we are concerned with the simulation of blood flow in microvascular networks and the surrounding tissue. To reduce the computational complexity of this issue, the network structures are modeled by a one-dimensional graph,…
We present a novel approach for imaging the beating embryonic heart, based on combining two independent imaging channels to capture the full spatio-temporal information of the moving 3D structure. High-resolution, optically-sectioned image…
Larval zebrafish exhibit a variety of complex undulatory swimming patterns. This repertoire is controlled by the 300 neurons projecting from brain into spinal cord. Understanding how descending control signals shape the output of spinal…
In this work we present a novel publicly available stereo based 3D RGB dataset for multi-object zebrafish tracking, called 3D-ZeF. Zebrafish is an increasingly popular model organism used for studying neurological disorders, drug addiction,…
This work presents a biventricular electromechanical human heart model that is comprehensive and clinically relevant, integrating a realistic 3D heart geometry with both systemic and pulmonary hemodynamics. The model uses a two-way…
We have previously shown how to socially integrate a fish robot into a group of zebrafish thanks to biomimetic behavioural models. The models have to be calibrated on experimental data to present correct behavioural features. This…
Extensive studies suggested that fluid mechanical markers of intracranial aneurysms (IAs) derived from Computational Fluid Dynamics (CFD) can indicate disease progression risks, but to date this has not been translated clinically. This is…
Research on untethered micro-swimming robots is growing fast owing to their potential impact on minimally invasive medical procedures. Candidate propulsion mechanisms of robots are based on flagellar mechanisms of microorganisms such as…
This study investigates the hemodynamic behavior of blood flow in the aortic arch across anemic, diabetic, and healthy conditions using computational fluid dynamics (CFD) simulations with a non-Newtonian Carreau viscosity model. Velocity…
We introduce a multiphysics and geometric multiscale computational model, suitable to describe the hemodynamics of the whole human heart, driven by a four-chamber electromechanical model. We first present a study on the calibration of the…