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The pursuit of universal black-box optimization (BBO) algorithms is a longstanding goal. However, unlike domains such as language or vision, where scaling structured data has driven generalization, progress in offline BBO remains hindered…

Machine Learning · Computer Science 2025-06-10 Rong-Xi Tan , Ming Chen , Ke Xue , Yao Wang , Yaoyuan Wang , Sheng Fu , Chao Qian

Recent research in molecular discovery has primarily been devoted to small, drug-like molecules, leaving many similarly important applications in material design without adequate technology. These applications often rely on more complex…

Recent advances in language models opened new opportunities to address complex schema matching tasks. Schema matching approaches have been proposed that demonstrate the usefulness of language models, but they have also uncovered important…

Databases · Computer Science 2025-06-18 Yurong Liu , Eduardo Pena , Aecio Santos , Eden Wu , Juliana Freire

Machine learning based methods have shown potential for optimizing existing molecules with more desirable properties, a critical step towards accelerating new chemical discovery. Here we propose QMO, a generic query-based molecule…

Machine Learning · Computer Science 2022-04-21 Samuel Hoffman , Vijil Chenthamarakshan , Kahini Wadhawan , Pin-Yu Chen , Payel Das

Mamba-based architectures have shown to be a promising new direction for deep learning models owing to their competitive performance and sub-quadratic deployment speed. However, current Mamba multi-modal large language models (MLLM) are…

Computer Vision and Pattern Recognition · Computer Science 2024-10-10 Yifei Xing , Xiangyuan Lan , Ruiping Wang , Dongmei Jiang , Wenjun Huang , Qingfang Zheng , Yaowei Wang

The goal of the Collaborative Research Center 1625 is the establishment of a scientific basis for the atomic-scale understanding and design of multifunctional compositionally complex solid solution surfaces. Next to materials synthesis in…

Automation is one of the cornerstones of contemporary material discovery. Bayesian optimization (BO) is an essential part of such workflows, enabling scientists to leverage prior domain knowledge into efficient exploration of a large…

Machine Learning · Computer Science 2024-05-30 Agustinus Kristiadi , Felix Strieth-Kalthoff , Marta Skreta , Pascal Poupart , Alán Aspuru-Guzik , Geoff Pleiss

The goal of Multi-task Bayesian Optimization (MBO) is to minimize the number of queries required to accurately optimize a target black-box function, given access to offline evaluations of other auxiliary functions. When offline datasets are…

Machine Learning · Computer Science 2022-03-11 Kourosh Hakhamaneshi , Pieter Abbeel , Vladimir Stojanovic , Aditya Grover

Perceptual image compression focuses on preserving high visual quality under low-bitrate constraints. Most existing approaches to perceptual compression leverage the strong generative capabilities of generative adversarial networks or…

Computer Vision and Pattern Recognition · Computer Science 2026-05-07 Jiaqian Zhang , Hao Wei , Chenyang Ge , Yanhui Zhou

Recent advancements in artificial intelligence have sparked interest in scientific assistants that could support researchers across the full spectrum of scientific workflows, from literature review to experimental design and data analysis.…

Computational design problems arise in a number of settings, from synthetic biology to computer architectures. In this paper, we aim to solve data-driven model-based optimization (MBO) problems, where the goal is to find a design input that…

Machine Learning · Computer Science 2021-07-15 Brandon Trabucco , Aviral Kumar , Xinyang Geng , Sergey Levine

We propose a small, shared core ontology for particle accelerators that provides a semantic backbone for interoperable data and workflows across facilities. The ontology names key device types, signals, parameters, and regions, and relates…

Accelerator Physics · Physics 2025-12-02 Chris Tennant

First principles based exploration of chemical space deepens our understanding of chemistry, and might help with the design of new materials or experiments. Due to the computational cost of quantum chemistry methods and the immens number of…

Chemical Physics · Physics 2020-08-18 Bing Huang , O. Anatole von Lilienfeld

Modern digital ecosystems, spanning software, hardware, learning models, datasets, and cryptographic products, continue to grow in complexity, making it difficult for organizations to understand and manage component dependencies. Bills of…

Cryptography and Security · Computer Science 2026-01-21 Shuai Zhang , Minzhao Lyu , Hassan Habibi Gharakheili

Scientific machine learning research spans diverse domains and data modalities, yet existing benchmark efforts remain siloed and lack standardization. This makes novel and transformative applications of machine learning to critical…

In today's uncertain and competitive market, where enterprises are subjected to increasingly shortened product life-cycles and frequent volume changes, reconfigurable manufacturing systems (RMS) applications play a significant role in the…

Systems and Control · Electrical Eng. & Systems 2023-01-02 Carlos Alberto Barrera-Diaz , Amir Nourmohammdi , Henrik Smedberg , Tehseen Aslam , Amos H. C. Ng

Artificial intelligence is transforming molecular and materials science, but its growing computational and data demands raise critical sustainability challenges. In this Perspective, we examine resource considerations across the AI-driven…

The advent of single-cell multi-omics technologies has enabled the simultaneous profiling of diverse omics layers within individual cells. Integrating such multimodal data provides unprecedented insights into cellular identity, regulatory…

Cell Behavior · Quantitative Biology 2025-06-27 Zhen Yuan , Shaoqing Jiao , Yihang Xiao , Jiajie Peng

The development of materials science is undergoing a shift from empirical approaches to data-driven and algorithm-oriented research paradigm. The state-of-the-art platforms are confined to inorganic crystals, with limited chemical space,…

Materials Science · Physics 2025-07-08 Jifeng Wang , Jiazhe Ju , Ying Wang

Decades of hardware, methodological, and algorithmic development have propelled molecular dynamics (MD) simulations to the forefront of materials-modeling techniques, bridging the gap between electronic-structure theory and continuum…

Soft Condensed Matter · Physics 2020-11-11 Tristan Bereau