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High-dimensional Bayesian Optimization (BO) has attracted significant attention in recent research. However, existing methods have mainly focused on optimizing in continuous domains, while combinatorial (ordinal and categorical) and mixed…

Machine Learning · Statistics 2025-08-26 Lam Ngo , Huong Ha , Jeffrey Chan , Hongyu Zhang

Object detectors trained on fully-annotated data currently yield state of the art performance but require expensive manual annotations. On the other hand, weakly-supervised detectors have much lower performance and cannot be used reliably…

Computer Vision and Pattern Recognition · Computer Science 2020-02-19 Linpu Fang , Hang Xu , Zhili Liu , Sarah Parisot , Zhenguo Li

Reproducibility and reusability of the results of data-based modeling studies are essential. Yet, there has been -- so far -- no broadly supported format for the specification of parameter estimation problems in systems biology. Here, we…

Biological image analysis has traditionally focused on measuring specific visual properties of interest for cells or other entities. A complementary paradigm gaining increasing traction is image-based profiling - quantifying many distinct…

Computer Vision and Pattern Recognition · Computer Science 2025-07-03 Alán F. Muñoz , Tim Treis , Alexandr A. Kalinin , Shatavisha Dasgupta , Fabian Theis , Anne E. Carpenter , Shantanu Singh

In self-supervised skeleton-based action recognition, the mask reconstruction paradigm is gaining interest in enhancing model refinement and robustness through effective masking. However, previous works primarily relied on a single masking…

Computer Vision and Pattern Recognition · Computer Science 2024-09-27 Xinpeng Yin , Wenming Cao

State-space models (SSMs) are commonly used to model time series data where the observations depend on an unobserved latent process. However, inference on the model parameters of an SSM can be challenging, especially when the likelihood of…

Computation · Statistics 2023-08-08 Mary Llewellyn , Ruth King , Víctor Elvira , Gordon Ross

Patients are increasingly turning to online health Q&A communities for social support to improve their well-being. However, when this support received does not align with their specific needs, it may prove ineffective or even detrimental.…

Computers and Society · Computer Science 2025-03-25 Junwei Kuang , Liang Yang , Shaoze Cui , Weiguo Fan

Despite all the benefits of automated hyperparameter optimization (HPO), most modern HPO algorithms are black-boxes themselves. This makes it difficult to understand the decision process which leads to the selected configuration, reduces…

Machine Learning · Computer Science 2023-02-14 Julia Moosbauer , Giuseppe Casalicchio , Marius Lindauer , Bernd Bischl

Summary: Microbiome HiFi Amplicon Sequence Simulator (MHASS) creates realistic synthetic PacBio HiFi amplicon sequencing datasets for microbiome studies, by integrating genome-aware abundance modeling, realistic dual-barcoding strategies,…

Genomics · Quantitative Biology 2025-09-17 Rye Howard-Stone , Ion Mandoiu

As one of Bayesian analysis tools, Hidden Markov Model (HMM) has been used to in extensive applications. Most HMMs are solved by Baum-Welch algorithm (BWHMM) to predict the model parameters, which is difficult to find global optimal…

Machine Learning · Statistics 2018-11-09 L. Chang , Yacine Ouzrout , Antoine Nongaillard , Abdelaziz Bouras

When using machine learning (ML) techniques, users typically need to choose a plethora of algorithm-specific parameters, referred to as hyperparameters. In this paper, we compare the performance of two algorithms, particle swarm…

Data Analysis, Statistics and Probability · Physics 2023-10-16 Laurits Tani , Christian Veelken

Probabilistic modeling provides the capability to represent and manipulate uncertainty in data, models, predictions and decisions. We are concerned with the problem of learning probabilistic models of dynamical systems from measured data.…

Computation · Statistics 2018-03-14 Thomas B. Schön , Andreas Svensson , Lawrence Murray , Fredrik Lindsten

Cosmological emulators of observables such as the Cosmic Microwave Background (CMB) spectra and matter power spectra commonly use training data sampled from a Latin hypercube. This method often incurs high computational costs by covering…

Cosmology and Nongalactic Astrophysics · Physics 2024-05-03 Andreas Nygaard , Emil Brinch Holm , Steen Hannestad , Thomas Tram

Hyperparameter selection in continual learning scenarios is a challenging and underexplored aspect, especially in practical non-stationary environments. Traditional approaches, such as grid searches with held-out validation data from all…

Machine Learning · Computer Science 2024-06-21 Rudy Semola , Julio Hurtado , Vincenzo Lomonaco , Davide Bacciu

We study the use of hypermodels to represent epistemic uncertainty and guide exploration. This generalizes and extends the use of ensembles to approximate Thompson sampling. The computational cost of training an ensemble grows with its…

Machine Learning · Computer Science 2020-06-16 Vikranth Dwaracherla , Xiuyuan Lu , Morteza Ibrahimi , Ian Osband , Zheng Wen , Benjamin Van Roy

$\texttt{HEPfit}$ is a flexible open-source tool which, given the Standard Model or any of its extensions, allows to $\textit{i)}$ fit the model parameters to a given set of experimental observables; $\textit{ii)}$ obtain predictions for…

The selection of hyper-parameters is critical in Deep Learning. Because of the long training time of complex models and the availability of compute resources in the cloud, "one-shot" optimization schemes - where the sets of hyper-parameters…

Machine Learning · Computer Science 2017-06-13 Olivier Bousquet , Sylvain Gelly , Karol Kurach , Olivier Teytaud , Damien Vincent

Deep learning has achieved impressive performance in many domains, such as computer vision and natural language processing, but its advantage over classical shallow methods on tabular datasets remains questionable. It is especially…

Machine Learning · Computer Science 2023-08-25 Witold Wydmański , Oleksii Bulenok , Marek Śmieja

Mass spectrometry, commonly used for protein identification, generates a massive number of spectra that need to be matched against a large database. In reality, most of them remain unidentified or mismatched due to unexpected…

Distributed, Parallel, and Cluster Computing · Computer Science 2023-01-03 Jaeyoung Kang , Weihong Xu , Wout Bittremieux , Tajana Rosing

HIPSTER (Heavily Ionising Particle Standard Toolkit for Event Recognition) is an open source Python package designed to facilitate the use of TensorFlow in a high energy physics analysis context. The core functionality of the software is…

High Energy Physics - Experiment · Physics 2019-09-18 Adrian Bevan , Thomas Charman , Jonathan Hays