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Causal inference is essential for data-driven decision-making, as it aims to uncover causal relationships from observational data. However, identifying causality remains challenging due to the potential for confounding and the distinction…

Machine Learning · Statistics 2026-05-08 Tianyu Yang , Md. Noor-E-Alam

Cell lineage decisions occur in three-dimensional spatial patterns that are difficult to identify by eye. There is an ongoing effort to replicate such patterns using mathematical modeling. One approach uses long ranging cell-cell…

Cell Behavior · Quantitative Biology 2022-12-21 Robin Dirk , Jonas L. Fischer , Simon Schardt , Markus J. Ankenbrand , Sabine C. Fischer

Clinical cystoscopy, the current standard for bladder cancer diagnosis, suffers from significant reliance on physician expertise, leading to variability and subjectivity in diagnostic outcomes. There is an urgent need for objective,…

Image and Video Processing · Electrical Eng. & Systems 2025-08-22 Jinliang Yu , Mingduo Xie , Yue Wang , Tianfan Fu , Xianglai Xu , Jiajun Wang

Artificial intelligence (AI) has transformed digital pathology by enabling biomarker prediction from high-resolution whole-slide images (WSIs). However, current methods are computationally inefficient, processing thousands of redundant…

Computational pathology, integrating computational methods and digital imaging, has shown to be effective in advancing disease diagnosis and prognosis. In recent years, the development of machine learning and deep learning has greatly…

Image and Video Processing · Electrical Eng. & Systems 2025-02-25 Jiamu Wang , Chang-Su Kim , Jin Tae Kwak

Deploying deep learning models for plant disease detection on edge devices such as IoT sensors, smartphones, and embedded systems is severely constrained by limited computational resources and energy budgets. To address this challenge, we…

Computer Vision and Pattern Recognition · Computer Science 2026-01-27 Weloday Fikadu Moges , Jianmei Su , Amin Waqas

Nuclei segmentation and classification is a significant process in pathology image analysis. Deep learning-based approaches have greatly contributed to the higher accuracy of this task. However, those approaches suffer from the imbalanced…

Computer Vision and Pattern Recognition · Computer Science 2023-06-27 Hyun-Jic Oh , Won-Ki Jeong

In this paper, we introduce a Bayesian deep learning based model for segmenting the photoreceptor layer in pathological OCT scans. Our architecture provides accurate segmentations of the photoreceptor layer and produces pixel-wise epistemic…

Advancements in cytometry technologies have led to a remarkable increase in the number of markers that can be analyzed simultaneously, presenting significant challenges in data analysis. Traditional approaches, such as dimensional reduction…

Quantitative Methods · Quantitative Biology 2025-07-01 Masahiro Ono

Cell instance segmentation is a new and challenging task aiming at joint detection and segmentation of every cell in an image. Recently, many instance segmentation methods have applied in this task. Despite their great success, there still…

Computer Vision and Pattern Recognition · Computer Science 2022-08-18 Menghao Li , Wenquan Feng , Shuchang Lyu , Lijiang Chen , Qi Zhao

We describe a method for cell-division detection based on a geometric-driven descriptor that can be represented as a 5-layers processing network, based mainly on wavelet filtering and a test for mirror symmetry between pairs of pixels.…

Computer Vision and Pattern Recognition · Computer Science 2013-04-11 Marcelo Cicconet , Italo Lima , Davi Geiger , Kris Gunsalus

Biological and cellular systems are often modeled as graphs in which vertices represent objects of interest (genes, proteins, drugs) and edges represent relational ties among these objects (binds-to, interacts-with, regulates). This…

Machine Learning · Statistics 2017-03-16 Jose Lugo-Martinez , Predrag Radivojac

Biomarker discovery is vital in advancing personalized medicine, offering insights into disease diagnosis, prognosis, and therapeutic efficacy. Traditionally, the identification and validation of biomarkers heavily depend on extensive…

Machine Learning · Computer Science 2024-09-25 Wangyang Ying , Dongjie Wang , Xuanming Hu , Ji Qiu , Jin Park , Yanjie Fu

Matching cells over time has long been the most difficult step in cell tracking. In this paper, we approach this problem by recasting it as a classification problem. We construct a feature set for each cell, and compute a feature difference…

Computer Vision and Pattern Recognition · Computer Science 2017-11-01 Quan Wang , Yan Ou , A. Agung Julius , Kim L. Boyer , Min Jun Kim

This paper explores the point set representation for tubular structure extraction tasks. Compared with the traditional mask representation, the point set representation enjoys its flexibility and representation ability, which would not be…

Computer Vision and Pattern Recognition · Computer Science 2022-09-14 Dong Wang , Zhao Zhang , Ziwei Zhao , Yuhang Liu , Yihong Chen , Liwei Wang

Automatic cell tracking in dense environments is plagued by inaccurate correspondences and misidentification of parent-offspring relationships. In this paper, we introduce a novel cell tracking algorithm named DenseTrack, which integrates…

Image and Video Processing · Electrical Eng. & Systems 2024-07-08 Tanjin Taher Toma , Yibo Wang , Andreas Gahlmann , Scott T. Acton

In view of the recent paradigm shift in deep AI based image processing methods, medical image processing has advanced considerably. In this study, we propose a novel deep neural network (DNN), entitled InceptNet, in the scope of medical…

Image and Video Processing · Electrical Eng. & Systems 2023-09-06 Amirhossein Sajedi , Mohammad Javad Fadaeieslam

In this work we propose an approach to select the classification method and features, based on the state-of-the-art, with best performance for diagnostic support through peripheral blood smear images of red blood cells. In our case we used…

Machine Learning · Computer Science 2020-10-12 Nataša Petrović , Gabriel Moyà-Alcover , Antoni Jaume-i-Capó , Manuel González-Hidalgo

Leaf wetness detection is a crucial task in agricultural monitoring, as it directly impacts the prediction and protection of plant diseases. However, existing sensing systems suffer from limitations in robustness, accuracy, and…

Computer Vision and Pattern Recognition · Computer Science 2025-07-31 Yimeng Liu , Maolin Gan , Yidong Ren , Gen Li , Jingkai Lin , Younsuk Dong , Zhichao Cao

We introduce a machine learning-based method for fully automated diagnosis of sickle cell disease of poor-quality unstained images of a mobile microscope. Our method is capable of distinguishing between diseased, trait (carrier), and normal…

Computer Vision and Pattern Recognition · Computer Science 2021-03-31 Sahar A. Nasser , Debjani Paul , Suyash P. Awate
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