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Image normalization is a building block in medical image analysis. Conventional approaches are customarily utilized on a per-dataset basis. This strategy, however, prevents the current normalization algorithms from fully exploiting the…

Machine Learning · Computer Science 2020-10-06 Pierre-Luc Delisle , Benoit Anctil-Robitaille , Christian Desrosiers , Herve Lombaert

Medical image registration is a critical component of clinical imaging workflows, enabling accurate longitudinal assessment, multi-modal data fusion, and image-guided interventions. Intensity-based approaches often struggle with…

Computer Vision and Pattern Recognition · Computer Science 2026-03-17 Eytan Kats , Mattias P. Heinrich

We propose a registration algorithm for 2D CT/MRI medical images with a new unsupervised end-to-end strategy using convolutional neural networks. The contributions of our algorithm are threefold: (1) We transplant traditional image…

Computer Vision and Pattern Recognition · Computer Science 2018-01-23 Siyuan Shan , Wen Yan , Xiaoqing Guo , Eric I-Chao Chang , Yubo Fan , Yan Xu

Accurate detection and segmentation of anatomical structures from ultrasound images are crucial for clinical diagnosis and biometric measurements. Although ultrasound imaging has been widely used with superiorities such as low cost and…

Computer Vision and Pattern Recognition · Computer Science 2016-07-08 Hao Chen , Yefeng Zheng , Jin-Hyeong Park , Pheng-Ann Heng , S. Kevin Zhou

Recent works in medical image registration have proposed the use of Implicit Neural Representations, demonstrating performance that rivals state-of-the-art learning-based methods. However, these implicit representations need to be optimized…

Image and Video Processing · Electrical Eng. & Systems 2023-10-04 Louis D. van Harten , Jaap Stoker , Ivana Išgum

Objective: Deformable image registration is a fundamental problem in medical image analysis, with applications such as longitudinal studies, population modeling, and atlas based image segmentation. Registration is often phrased as an…

Computer Vision and Pattern Recognition · Computer Science 2018-10-22 Simon Ekström , Filip Malmberg , Håkan Ahlström , Joel Kullberg , Robin Strand

With recent advances in computing hardware and surges of deep-learning architectures, learning-based deep image registration methods have surpassed their traditional counterparts, in terms of metric performance and inference time. However,…

Computer Vision and Pattern Recognition · Computer Science 2024-03-13 Bin Duan , Ming Zhong , Yan Yan

Brain image registration transforms a pair of images into one system with the matched imaging contents, which is of essential importance for brain image analysis. This paper presents a novel framework for unsupervised 3D brain image…

Computer Vision and Pattern Recognition · Computer Science 2019-07-04 Lihao Liu , Xiaowei Hu , Lei Zhu , Pheng-Ann Heng

Acquisition-to-acquisition signal intensity variations (non-standardness) are inherent in MR images. Standardization is a post processing method for correcting inter-subject intensity variations through transforming all images from the…

Computer Vision and Pattern Recognition · Computer Science 2015-05-18 Ulas Bagci , Jayaram K. Udupa , Li Bai

It's well-known that inverse problems are ill-posed and to solve them meaningfully one has to employ regularization methods. Traditionally, popular regularization methods have been the penalized Variational approaches. In recent years, the…

Machine Learning · Computer Science 2022-02-17 Abinash Nayak

Though, deep learning based medical image registration is currently starting to show promising advances, often, it still fells behind conventional frameworks in terms of registration accuracy. This is especially true for applications where…

Computer Vision and Pattern Recognition · Computer Science 2020-05-28 Lasse Hansen , Mattias P. Heinrich

We propose regularization schemes for deformable registration and efficient algorithms for their numerical approximation. We treat image registration as a variational optimal control problem. The deformation map is parametrized by its…

Optimization and Control · Mathematics 2016-09-09 Andreas Mang , George Biros

Deformable image registration is a fundamental task in medical imaging. Due to the large computational complexity of deformable registration of volumetric images, conventional iterative methods usually face the tradeoff between the…

Computer Vision and Pattern Recognition · Computer Science 2022-01-19 Kaicong Sun , Sven Simon

Learning-based medical image registration has matched the accuracy of conventional methods while offering superior computational efficiency. However, existing approaches suffer from poor generalization across diverse clinical scenarios,…

Computer Vision and Pattern Recognition · Computer Science 2026-05-25 Zi Li , Jianpeng Zhang , Tai Ma , Tony C. W. Mok , Yan-Jie Zhou , Zeli Chen , Xianghua Ye , Le Lu , Cheng Chen , Dakai Jin

When adopting a model-based formulation, solving inverse problems encountered in multiband imaging requires to define spatial and spectral regularizations. In most of the works of the literature, spectral information is extracted from the…

Image and Video Processing · Electrical Eng. & Systems 2023-07-03 Min Zhao , Nicolas Dobigeon , Jie Chen

The correlation of optical measurements with a correct pathology label is often hampered by imprecise registration caused by deformations in histology images. This study explores an automated multi-modal image registration technique…

Image and Video Processing · Electrical Eng. & Systems 2023-11-27 Lianne Feenstra , Maud Lambregts , Theo J. M Ruers , Behdad Dashtbozorg

In order to tackle the difficulty associated with the ill-posed nature of the image registration problem, regularization is often used to constrain the solution space. For most learning-based registration approaches, the regularization…

Computer Vision and Pattern Recognition · Computer Science 2022-03-03 Zhe Xu , Jie Luo , Donghuan Lu , Jiangpeng Yan , Sarah Frisken , Jayender Jagadeesan , William Wells , Xiu Li , Yefeng Zheng , Raymond Tong

Whole-body Positron Emission Tomography (PET) registration is essential for multi-parametric tumor characterization and assessment of metastatic disease progression. In deep learning-based deformable registration, the dense displacement…

Image and Video Processing · Electrical Eng. & Systems 2026-04-28 Xiangcen Wu , Ruohua Chen , Sichun Li , Qianye Yang , Sheng Liu , Jianjun Liu , Zhaoheng Xie

Deformable registration continues to be one of the key challenges in medical image analysis. While iconic registration methods have started to benefit from the recent advances in medical deep learning, the same does not yet apply for the…

Computer Vision and Pattern Recognition · Computer Science 2019-09-18 Lasse Hansen , Doris Dittmer , Mattias P. Heinrich

This tutorial covers biomedical image reconstruction, from the foundational concepts of system modeling and direct reconstruction to modern sparsity and learning-based approaches. Imaging is a critical tool in biological research and…

Image and Video Processing · Electrical Eng. & Systems 2021-03-12 Michael T. McCann , Michael Unser
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