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Proteins interact to form complexes to carry out essential biological functions. Computational methods have been developed to predict the structures of protein complexes. However, an important challenge in protein complex structure…

Machine Learning · Computer Science 2022-05-24 Xiao Chen , Alex Morehead , Jian Liu , Jianlin Cheng

In the restricted shortest paths problem, we are given a graph $G$ whose edges are assigned two non-negative weights: lengths and delays, a source $s$, and a delay threshold $D$. The goal is to find, for each target $t$, the length of the…

Data Structures and Algorithms · Computer Science 2024-10-23 Vikrant Ashvinkumar , Aaron Bernstein , Adam Karczmarz

Directed acyclic graphical models (DAGs) are often used to describe common structural properties in a family of probability distributions. This paper addresses the question of classifying DAGs up to an isomorphism. By considering Gaussian…

Information Theory · Computer Science 2014-12-24 Hajir Roozbehani , Yury Polyanskiy

Our approach to structural matrix rings defines them over preordered directed graphs. A grading of a structural matrix ring is called a good grading if its standard unit matrices are homogeneous. For a group $G$, a $G$ -grading set is a set…

Rings and Algebras · Mathematics 2018-07-11 John Dewitt , Kenneth L. Price

Let $D$ be an oriented graph with skew adjacency matrix $S(D)$. Two oriented graphs $D$ and $C$ are said to share the same generalized skew spectrum if $S(D)$ and $S(C)$ have the same eigenvalues, and $J-S(D)$ and $J-S(C)$ also have the…

Combinatorics · Mathematics 2025-04-25 Muhammad Raza , Obaid Ullah Ahmed , Mudassir Shabbir , Xenofon Koutsoukos , Waseem Abbas

In observational studies, the true causal model is typically unknown and needs to be estimated from available observational and limited experimental data. In such cases, the learned causal model is commonly represented as a partially…

Artificial Intelligence · Computer Science 2023-03-01 Malte Luttermann , Marcel Wienöbst , Maciej Liśkiewicz

Score-based graph generative models (SGGMs) have proven effective in critical applications such as drug discovery and protein synthesis. However, their theoretical behavior, particularly regarding convergence, remains underexplored. Unlike…

Machine Learning · Computer Science 2025-08-21 Junwei Su , Chuan Wu

Many interesting examples of operator algebras, both self-adjoint and non-self-adjoint, can be constructed from directed graphs. In this survey, we overview the construction of $C^*$-algebras from directed graphs and from two…

Operator Algebras · Mathematics 2022-09-07 Juliana Bukoski , Sushil Singla

Accurately reconstructing Gene Regulatory Networks (GRNs) is crucial for understanding gene functions and disease mechanisms. Single-cell RNA sequencing (scRNA-seq) technology provides vast data for computational GRN reconstruction. Since…

Molecular Networks · Quantitative Biology 2025-12-16 Rijie Xi , Weikang Xu , Wei Xiong , Yuannong Ye , Bin Zhao

There has been much recent interest in designing neural networks (NNs) with relaxed equivariance, which interpolate between exact equivariance and full flexibility for consistent performance gains. In a separate line of work, structured…

Machine Learning · Statistics 2025-04-21 Ashwin Samudre , Mircea Petrache , Brian D. Nord , Shubhendu Trivedi

Graphs can be used to represent and reason about systems and a variety of metrics have been devised to quantify their global characteristics. However, little is currently known about how to construct a graph or improve an existing one given…

Machine Learning · Computer Science 2021-10-28 Victor-Alexandru Darvariu , Stephen Hailes , Mirco Musolesi

Let $G$ be a strongly connected directed graph and $u,v,w\in V(G)$ be three vertices. Then $w$ strongly resolves $u$ to $v$ if there is a shortest $u$-$w$-path containing $v$ or a shortest $w$-$v$-path containing $u$. A set $R\subseteq…

Computational Complexity · Computer Science 2021-11-29 Yannick Schmitz , Egon Wanke

In this paper, we study the connectivity of a one-dimensional soft random geometric graph (RGG). The graph is generated by placing points at random on a bounded line segment and connecting pairs of points with a probability that depends on…

Probability · Mathematics 2021-01-04 Michael Wilsher , Carl P. Dettmann , Ayalvadi Ganesh

This paper addresses questions regarding controllability for `generic parameter' dynamical systems, i.e. the question whether a dynamical system is `structurally controllable'. Unlike conventional methods that deal with structural…

Optimization and Control · Mathematics 2010-06-29 Madhu N. Belur , Sivaramakrishnan Sivasubramanian

In this paper we define a way to get a bounded invertible automaton starting from a finite graph. It turns out that the corresponding automaton group is regular weakly branch over its commutator subgroup, contains a free semigroup on two…

Group Theory · Mathematics 2021-06-10 Matteo Cavaleri , Daniele D'Angeli , Alfredo Donno , Emanuele Rodaro

This paper focuses on the statistical analysis of shapes of data objects called shape graphs, a set of nodes connected by articulated curves with arbitrary shapes. A critical need here is a constrained registration of points (nodes to…

Computer Vision and Pattern Recognition · Computer Science 2023-08-15 Shenyuan Liang , Mauricio Pamplona Segundo , Sathyanarayanan N. Aakur , Sudeep Sarkar , Anuj Srivastava

This work deals with the generation of theoretical correlation matrices with specific sparsity patterns, associated to graph structures. We present a novel approach based on convex optimization, offering greater flexibility compared to…

Signal Processing · Electrical Eng. & Systems 2025-02-26 Ali Fakhar , Kévin Polisano , Irène Gannaz , Sophie Achard

Graph neural networks (GNNs) have emerged as powerful tools to accurately predict materials and molecular properties in computational discovery pipelines. In this article, we exploit the invertible nature of these neural networks to…

Machine Learning · Computer Science 2024-06-06 Félix Therrien , Edward H. Sargent , Oleksandr Voznyy

While deep learning has revolutionized the prediction of rigid protein structures, modelling the conformational ensembles of Intrinsically Disordered Proteins (IDPs) remains a key frontier. Current AI paradigms present a trade-off: Protein…

Biomolecules · Quantitative Biology 2025-12-19 Eoin Quinn , Marco Carobene , Jean Quentin , Sebastien Boyer , Miguel Arbesú , Oliver Bent

We introduce the use of high order automatic differentiation, implemented via the algebra of truncated Taylor polynomials, in genetic programming. Using the Cartesian Genetic Programming encoding we obtain a high-order Taylor representation…

Neural and Evolutionary Computing · Computer Science 2016-11-16 Dario Izzo , Francesco Biscani , Alessio Mereta
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