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We have evaluated the performance of a fine pitch CdTe Double-sided Strip Detector (CdTe-DSD), which was originally developed for the focal plane detector of a hard X-ray telescope to observe the Sun. The detector has a thickness of 750 um…

Instrumentation and Methods for Astrophysics · Physics 2020-08-04 Kento Furukawa , Shunsaku Nagasawa , Lindsay Glesener , Miho Katsuragawa , Shin'ichiro Takeda , Shin Watanabe , Tadayuki Takahashi

Cone-beam computed tomography (CBCT) is routinely collected during image-guided radiation therapy (IGRT) to provide updated patient anatomy information for cancer treatments. However, CBCT images often suffer from streaking artifacts and…

Computer Vision and Pattern Recognition · Computer Science 2023-11-02 Jiarui Zhu , Werxing Chen , Hongfei Sun , Shaohua Zhi , Jing Qin , Jing Cai , Ge Ren

Speckle is an intrinsic pattern in optical coherence tomography (OCT) that obscures fine image features and degrades effective resolution. In this study, we propose a numerical speckle reduction method based on the dispersed scatterer model…

X-ray scatter remains a major physics challenge in volumetric computed tomography (CT), whose physical and statistical behaviors have been commonly leveraged in order to eliminate its impact on CT image quality. In this work, we conduct an…

Medical Physics · Physics 2021-03-05 Tao Zhang , Zhiqiang Chen , Hao Zhou , N. Robert Bennett , Adam S. Wang , Hewei Gao

Dynamic scattering remains a significant challenge to the practical deployment of anti-scattering imaging. Existing methods, such as transmission matrix measurements, iterative wavefront shaping, and optical phase conjugation, depend on a…

A variety of on-orbit imaging and spectroscopic observations are used to characterize the Charge Transfer Efficiency (CTE) of the Charge-Coupled Device (CCD) of the Space Telescope Imaging Spectrograph (STIS) aboard the Hubble Space…

Astrophysics · Physics 2009-11-11 Paul Goudfrooij , Ralph C. Bohlin , Jesus Maiz-Apellaniz , Randy A. Kimble

Purpose: Developing photon-counting CT detectors requires understanding the impact of parameters such as converter material, absorption length and pixel size. We apply a novel linear-systems framework, incorporating spatial and energy…

Medical Physics · Physics 2020-03-03 Mats Persson , Adam Wang , Norbert J. Pelc

IR microspectroscopy of single biological cells is challenged by strong light scattering, which produces baseline effects and peak distortions in the IR spectra and hinders the direct extraction of chemical information. Current methods for…

We present extensive simulation studies on the performance of algorithms for the Compton sequence reconstruction used for the development of a portable spectroscopic instrument (COCAE), with the capability to localize and identify…

Nuclear Experiment · Physics 2015-03-17 K. Karafasoulis , K. Zachariadou , C. Potiriadis , S. Seferlis , I. Kaissas , D. Loukas , C. Lambropoulos

Microstructure characterisation has been greatly enhanced through the use of electron backscatter diffraction (EBSD), where rich maps are generated through analysis of the crystal phase and orientation in the scanning electron microscope…

Materials Science · Physics 2018-11-15 Vivian S Tong , Alexander J Knowles , David Dye , T Ben Britton

Our interest has been to study the effect that scattered radiation has on contrast, signal-to-noise ratio and thickness reconstruction in digital mammographies. Using the GEANT code we have performed Monte-Carlo simulations of 25 kVp Mo/Mo…

Medical Physics · Physics 2009-09-29 Varlen Grabski , Maria-Ester Brandan

In X-ray imaging, photons are transmitted through and absorbed by the subject, but are also scattered in significant quantities. Previous attempts to use scattered photons for biological imaging used pencil or fan beam illumination. Here we…

Flat-panel cone-beam CT (CBCT) has been applied clinically in a number of high-resolution applications. Increasing geometric magnification can potentially improve resolution, but also increases blur due to an extended x-ray focal-spot. We…

Medical Physics · Physics 2016-10-18 Steven Tilley , Wojciech Zbijewski , Jeffrey H. Siewerdsen , J. Webster Stayman

With the growing technology of photon-counting detectors (PCD), spectral CT is a widely concerned topic which has the potential of material differentiation. However, due to some non-ideal factors such as cross talk and pulse pile-up of the…

Medical Physics · Physics 2020-07-21 Ao Zheng , Hongkai Yang , Li Zhang , Yuxiang Xing

We present two methods that combine image reconstruction and edge detection in computed tomography (CT) scans. Our first method is as an extension of the prominent filtered backprojection algorithm. In our second method we employ…

Numerical Analysis · Mathematics 2021-10-14 Jürgen Frikel , Simon Göppel , Markus Haltmeier

A photon-counting silicon strip detector with two energy thresholds was investigated for spectral X-ray imaging in a mammography system. Preliminary studies already indicate clinical benefit of the detector, and the purpose of the present…

Instrumentation and Detectors · Physics 2021-01-21 Erik Fredenberg , Mats Lundqvist , Bjorn Cederstrom , Magnus Aslund , Mats Danielsson

We study the photon detection efficiency and position resolution of the electromagnetic calorimeter (EMC) of the BESIII experiment. The control sample of the initial-state-radiation (ISR) process of $e^+e^-\rightarrow \gamma \mu^+\mu^-$ is…

High Energy Physics - Experiment · Physics 2018-10-04 Vindhyawasini Prasad , Chunxiu Liu , Xiaobin Ji , Weidong Li , Huaimin Liu , Xinchou Lou

Objective: Long-axial field-of-view (LAFOV) positron emission tomography (PET) systems allow higher sensitivity, with an increased number of detected lines of response induced by a larger angle of acceptance. However, this extended angle…

Varian Medical Systems has manufactured and recently put into operation a clinically-applicable solution for image-guided radiation therapy. Cone-beam CT imaging, one of the operation modes of the imaging unit of this device, aims at…

Medical Physics · Physics 2007-05-23 Evangelos Matsinos , Wolfgang Kaissl

Many optical measurement techniques, such as light scattering from wavelength-scale particles or detecting motion from a surface with an optical lever, encode information in a complex radiation pattern. Extracting all available information…

Quantum Physics · Physics 2025-12-22 Youssef Tawfik , Shan Hao , Thomas P. Purdy