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Hybrid optimization algorithms have gained popularity as it has become apparent there cannot be a universal optimization strategy which is globally more beneficial than any other. Despite their popularity, hybridization frameworks require…

Neural and Evolutionary Computing · Computer Science 2013-03-15 Hassan A. Bashir , Richard S. Neville

The Soft Happy Colouring (SHC) problem, a mathematical framework for identifying homophilic network structures, seeks to maximise the number of $\rho$-happy vertices, i.e. vertices with at least a proportion $\rho$ of neighbours that share…

Social and Information Networks · Computer Science 2026-04-15 Mohammad Hadi Shekarriz , Asef Nazari , Dhananjay Thiruvady

The study of the evolution of coronal holes (CHs) is especially important in the context of high-speed solar wind streams (HSS) emanating from them. Stream interaction regions may deliver large amount of energy into the Earths system, cause…

Recent advancements in spatial transcriptomics technologies allow researchers to simultaneously measure RNA expression levels for hundreds to thousands of genes while preserving spatial information within tissues, providing critical…

Methodology · Statistics 2025-07-31 Catherine Higgins , Jingyi Jessica Li , Michelle Carey

To predict the complex chemical evolution in multicomponent alloys, it is highly desirable to have accurate atomistic simulation methods capable of reaching sufficiently large spatial and temporal scales. In this work, we advance the…

Materials Science · Physics 2025-12-08 Xianglin Liu , Kai Yang , Fanli Zhou , Pengxiang Xu

Recent imaging data for single bacterial cells reveal that their mean sizes grow exponentially in time and that their size distributions collapse to a single curve when rescaled by their means. An analogous result holds for the…

Statistical Mechanics · Physics 2014-07-14 Srividya Iyer-Biswas , Gavin E. Crooks , Norbert F. Scherer , Aaron R. Dinner

Modeling the chemistry of molecular clouds is critical to accurately simulating their evolution. To reduce computational cost, 3D simulations generally restrict their chemistry to species with strong heating and cooling effects.…

Astrophysics of Galaxies · Physics 2023-07-24 M. Panessa , D. Seifried , S. Walch , B. Gaches , A. T. Barnes , F. Bigiel , L. Neumann

Cellular signaling networks have evolved to cope with intrinsic fluctuations, coming from the small numbers of constituents, and the environmental noise. Stochastic chemical kinetics equations govern the way biochemical networks process…

Quantitative Methods · Quantitative Biology 2009-11-13 Yueheng Lan , Peter G. Wolynes , Garegin A. Papoian

We present cosmological hydrodynamical simulations of galaxy clusters aimed at studying the process of metal enrichment of the intra--cluster medium (ICM). These simulations have been performed by implementing a detailed model of chemical…

Astrophysics · Physics 2009-11-13 L. Tornatore , S. Borgani , K. Dolag , F. Matteucci

We present a new chemodynamical code - Ramses-CH - for use in simulating the self-consistent evolution of chemical and hydrodynamical properties of galaxies within a fully cosmological framework. We build upon the adaptive mesh refinement…

Astrophysics of Galaxies · Physics 2015-06-04 C. Gareth Few , Stephanie Courty , Brad K. Gibson , Daisuke Kawata , Francesco Calura , Romain Teyssier

The bottom-up construction of synthetic cells is one of the most intriguing and interesting research arenas in synthetic biology. Synthetic cells are built by encapsulating biomolecules inside lipid vesicles (liposomes), allowing the…

Computational Engineering, Finance, and Science · Computer Science 2013-10-01 Giordano Rampioni , Luisa Damiano , Marco Messina , Francesca D'Angelo , Livia Leoni , Pasquale Stano

Stochastic evolution underpins several approaches to the dynamics of open quantum systems, such as random modulation of Hamiltonian parameters, the stochastic Schrodinger equation (SSE), and the stochastic Liouville equation (SLE). These…

Quantum Physics · Physics 2026-01-22 Pietro De Checchi , Federico Gallina , Barbara Fresch , Giulio G. Giusteri

Cells exhibit a wide variety of different shapes. This diversity poses a challenge for computational approaches that attempt to shed light on the role cell geometry plays in regulating cell physiology and behavior. The simulation platform…

Quantitative Methods · Quantitative Biology 2020-03-31 Thorsten Prüstel , Martin Meier-Schellersheim

We present a new statistical algorithm of Chemical Evolution implemented into the Tree-SPH code developed by Lia & Carraro (2000 MNRAS 314, 145).

Astrophysics · Physics 2007-05-23 G. Carraro , L. Portinari , C. Lia

Comprehensive simulations of the entire biochemistry of cells have great potential to help physicians treat disease and help engineers design biological machines. But such simulations must model networks of millions of molecular species and…

Molecular Networks · Quantitative Biology 2020-05-22 Arthur P. Goldberg , David R. Jefferson , John A. P. Sekar , Jonathan R. Karr

We use our unified chemical and spectrophotometric evolutionary synthesis code to describe galaxies of various Hubble types. With stellar evolutionary tracks and element yields for 5 different metallicities we follow the spectrophotometric…

Astrophysics · Physics 2007-05-23 U. Fritze - v. Alvensleben , U. Lindner , K. J. Fricke

Biological diversity has evolved despite the essentially infinite complexity of protein sequence space. We present a hierarchical approach to the efficient searching of this space and quantify the evolutionary potential of our approach with…

Statistical Mechanics · Physics 2009-10-31 Leonard D. Bogarad , Michael W. Deem

From observations, column density ratios or integrated intensity ratios between some species exhibit monotonic increase or decrease along with the evolution of high-mass star-forming regions (HMSFRs). Such ratios are defined as chemical…

Astrophysics of Galaxies · Physics 2025-02-27 Yao Wang , Fujun Du , Youxin Wang , Hongchi Wang , Jiangshui Zhang

At the cellular scale, biochemical processes are governed by random interactions between reactant molecules with small copy counts, leading to behavior that is inherently stochastic. Such systems are often modeled as continuous-time Markov…

Data Structures and Algorithms · Computer Science 2015-09-02 Kevin R. Sanft , Hans G. Othmer

We present a new approach for chemical evolution modelling, specifically designed to investigate the chemical properties of dwarf galaxies in a full cosmological framework. In particular, we focus on the Sculptor dwarf spheroidal galaxy as…

Astrophysics of Galaxies · Physics 2015-06-16 Donatella Romano , Else Starkenburg