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Related papers: Qibitz: Mining PubMed for Repurposable Drugs

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PubTator 3.0 (https://www.ncbi.nlm.nih.gov/research/pubtator3/) is a biomedical literature resource using state-of-the-art AI techniques to offer semantic and relation searches for key concepts like proteins, genetic variants, diseases, and…

Computation and Language · Computer Science 2024-01-23 Chih-Hsuan Wei , Alexis Allot , Po-Ting Lai , Robert Leaman , Shubo Tian , Ling Luo , Qiao Jin , Zhizheng Wang , Qingyu Chen , Zhiyong Lu

The exponential growth in scholarly publications necessitates advanced tools for efficient article retrieval, especially in interdisciplinary fields where diverse terminologies are used to describe similar research. Traditional…

Many users turn to document retrieval systems (e.g. search engines) to seek answers to controversial questions. Answering such user queries usually require identifying responses within web documents, and aggregating the responses based on…

Computation and Language · Computer Science 2022-06-14 Sihao Chen , Siyi Liu , Xander Uyttendaele , Yi Zhang , William Bruno , Dan Roth

Peptides offer great biomedical potential and serve as promising drug candidates. Currently, the majority of approved peptide drugs are directly derived from well-explored natural human peptides. It is quite necessary to utilize advanced…

Biomolecules · Quantitative Biology 2024-01-29 Yipin Lei , Xu Wang , Meng Fang , Han Li , Xiang Li , Jianyang Zeng

Many web-search queries serve as the beginning of an exploration of an unknown space of information, rather than looking for a specific web page. To answer such queries effec- tively, the search engine should attempt to organize the space…

Information Retrieval · Computer Science 2014-01-17 Fei Wu , Jayant Madhavan , Alon Halevy

Computational drug repositioning aims to discover new therapeutic diseases for marketed drugs and has the advantages of low cost, short development cycle, and high controllability compared to traditional drug development. The matrix…

Machine Learning · Computer Science 2021-11-30 Xinxing Yang , Genke Yangand Jian Chu

Information retrieval from distributed heterogeneous data sources remains a challenging issue. As the number of data sources increases more intelligent retrieval techniques, focusing on information content and semantics, are required.…

Databases · Computer Science 2007-07-06 K. Munir , M. Odeh , R. McClatchey , S. Khan , I. Habib

Conventional optimization methodologies may be hindered when the automated search is stuck into local optima because of a deceptive objective function landscape. Consequently, open ended search methodologies, such as novelty search, have…

Neural and Evolutionary Computing · Computer Science 2020-05-22 Michail-Antisthenis Tsompanas , Larry Bull , Andrew Adamatzky , Igor Balaz

With the growing demand to fit fine-grained user intents, faceted query-by-example (QBE), which retrieves similar documents conditioned on specific facets, has gained recent attention. However, prior approaches mainly depend on…

Information Retrieval · Computer Science 2024-12-03 Heejin Do , Sangwon Ryu , Jonghwi Kim , Gary Geunbae Lee

Exploratory search starts with ill-defined goals and involves browsing, learning, and formulating new targets for search. To fluidly support such dynamic search behaviours, we focus on devising interactive visual facets (IVF), visualising…

Human-Computer Interaction · Computer Science 2021-09-14 Chen He , Luana Micallef , Barış Serim , Tung Vuong , Tuukka Ruotsalo , Giulio Jacucci

Drug discovery (DD) has tremendously contributed to maintaining and improving public health. Hypothesizing that inhibiting protein misfolding can slow disease progression, researchers focus on target identification (Target ID) to find…

Quantitative Methods · Quantitative Biology 2025-01-29 Ziwen Li , Xiang 'Anthony' Chen , Youngseung Jeon

Pathology images of histopathology can be acquired from camera-mounted microscopes or whole slide scanners. Utilizing similarity calculations to match patients based on these images holds significant potential in research and clinical…

Image and Video Processing · Electrical Eng. & Systems 2024-03-25 H. R. Tizhoosh , Liron Pantanowitz

The Internet has revolutionized healthcare by offering medical information ubiquitously to patients via web search. The healthcare status, complex medical information needs of patients are expressed diversely and implicitly in their medical…

Computation and Language · Computer Science 2017-10-24 Chenwei Zhang , Nan Du , Wei Fan , Yaliang Li , Chun-Ta Lu , Philip S. Yu

Face recall is a basic human cognitive process performed routinely, e.g., when meeting someone and determining if we have met that person before. Assisting a subject during face recall by suggesting candidate faces can be challenging. One…

Machine Learning · Statistics 2016-04-29 Andres G. Abad , Luis I. Reyes Castro

We present ClinicalTrialsHub, an interactive search-focused platform that consolidates all data from ClinicalTrials.gov and augments it by automatically extracting and structuring trial-relevant information from PubMed research articles.…

Computation and Language · Computer Science 2026-03-20 Jiwoo Park , Ruoqi Liu , Avani Jagdale , Andrew Srisuwananukorn , Jing Zhao , Lang Li , Ping Zhang , Sachin Kumar

The rapid expansion of biomedical publications creates challenges for organizing knowledge and detecting emerging trends, underscoring the need for scalable and interpretable methods. Common clustering and topic modeling approaches such as…

Machine Learning · Computer Science 2026-02-25 Lana E. Yeganova , Won G. Kim , Shubo Tian , Natalie Xie , Donald C. Comeau , W. John Wilbur , Zhiyong Lu

Drug repurposing has attracted increasing attention from both the pharmaceutical industry and the research community. Many existing computational drug repurposing methods rely on preclinical data (e.g., chemical structures, drug targets),…

Quantitative Methods · Quantitative Biology 2020-07-28 Qianlong Wen , Ruoqi Liu , Ping Zhang

Colonoscopic Polyp Re-Identification aims to match the same polyp from a large gallery with images from different views taken using different cameras, which plays an important role in the prevention and treatment of colorectal cancer in…

Computer Vision and Pattern Recognition · Computer Science 2025-12-29 Suncheng Xiang , Xiaoyang Wang , Junjie Jiang , Hejia Wang , Dahong Qian

Academic Search is a search task aimed to manage and retrieve scientific documents like journal articles and conference papers. Personalization in this context meets individual researchers' needs by leveraging, through user profiles, the…

Information Retrieval · Computer Science 2025-07-21 Pranav Kasela , Gabriella Pasi , Raffaele Perego

Objectives. Major research and implementation efforts have been devoted to indexing articles according to the major topics discussed, but much less effort to indexing their publication types and study designs (collectively, PTs). In this…

Digital Libraries · Computer Science 2026-05-01 Neil R. Smalheiser , Joe D. Menke , Arthur W. Holt , Halil Kilicoglu , Jodi Schneider