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Standardized patients (SPs) are indispensable for clinical skills training but remain expensive and difficult to scale. Although large language model (LLM)-based virtual standardized patients (VSPs) have been proposed as an alternative,…

Computation and Language · Computer Science 2026-03-24 Bingquan Zhang , Xiaoxiao Liu , Yuchi Wang , Lei Zhou , Qianqian Xie , Benyou Wang

Training mental health clinicians to conduct standardized clinical assessments is challenging due to a lack of scalable, realistic practice opportunities, which can impact data quality in clinical trials. To address this gap, we introduce a…

Human-Computer Interaction · Computer Science 2025-12-30 Veronica Bossio Botero , Vijay Yadav , Jacob Ouyang , Anzar Abbas , Michelle Worthington

Background: Simulated patient systems are important in medical education and research, providing safe, integrative training environments and supporting clinical decision making. Advances in artificial intelligence (AI), especially large…

Simulated Patients (SPs) play a crucial role in clinical medical education by providing realistic scenarios for student practice. However, the high cost of training and hiring qualified SPs, along with the heavy workload and potential risks…

Computation and Language · Computer Science 2024-04-26 Yanzeng Li , Cheng Zeng , Jialun Zhong , Ruoyu Zhang , Minhao Zhang , Lei Zou

Objective Structured Clinical Examinations (OSCEs) are essential for medical training, but they require significant resources, including professional actors and expert medical feedback. Although Large Language Models (LLMs) have introduced…

Human-Computer Interaction · Computer Science 2025-08-20 Henrik Voigt , Yurina Sugamiya , Kai Lawonn , Sina Zarrieß , Atsuo Takanishi

Standardized patients (SPs) play a central role in clinical communication training but are costly, difficult to scale, and inconsistent. Large language model (LLM) based AI standardized patients (AI-SPs) promise flexible, on-demand…

Human-Computer Interaction · Computer Science 2026-04-07 Zhiqi Gao , Guo Zhu , Huarui Luo , Dongyijie Primo Pan , Haoming Tang , Bingquan Zhang , Jiahuan Pei , Jie Li , Benyou Wang

The recent rapid development of large language models (LLMs) has sparked a new wave of technological revolution in medical artificial intelligence (AI). While LLMs are designed to understand and generate text like a human, autonomous agents…

Artificial Intelligence · Computer Science 2025-01-20 Junkai Li , Yunghwei Lai , Weitao Li , Jingyi Ren , Meng Zhang , Xinhui Kang , Siyu Wang , Peng Li , Ya-Qin Zhang , Weizhi Ma , Yang Liu

VR simulation in Health Professions (HP) education demonstrates huge potential, but fixed learning content with little customization limits its application beyond lab environments. To address these limitations in the context of VR for…

Human-Computer Interaction · Computer Science 2025-03-04 Xiuqi Tommy Zhu , Heidi Cheerman , Minxin Cheng , Sheri Kiami , Leanne Chukoskie , Eileen McGivney

Simulations, although powerful in accurately replicating real-world systems, often remain inaccessible to non-technical users due to their complexity. Conversely, large language models (LLMs) provide intuitive, language-based interactions…

Computation and Language · Computer Science 2025-05-22 Jacob Kleiman , Kevin Frank , Joseph Voyles , Sindy Campagna

This paper proposes EvoAgent - an evolvable large language model (LLM) agent framework that integrates structured skill learning with a hierarchical sub-agent delegation mechanism. EvoAgent models skills as multi-file structured capability…

Artificial Intelligence · Computer Science 2026-04-27 Aimin Zhang , Jiajing Guo , Fuwei Jia , Chen Lv , Boyu Wang , Fangzheng Li

Medical Decision-Making (MDM) is a multi-faceted process that requires clinicians to assess complex multi-modal patient data patient, often collaboratively. Large Language Models (LLMs) promise to streamline this process by synthesizing…

Effective communication training is essential to preparing nurses for high-quality patient care. While standardized patient (SP) simulations provide valuable experiential learning, they are often costly and inflexible. Virtual patient (VP)…

Computation and Language · Computer Science 2025-06-03 Keyeun Lee , Seolhee Lee , Esther Hehsun Kim , Yena Ko , Jinsu Eun , Dahee Kim , Hyewon Cho , Haiyi Zhu , Robert E. Kraut , Eunyoung Suh , Eun-mee Kim , Hajin Lim

Effective communication is a crucial skill for healthcare providers since it leads to better patient health, satisfaction and avoids malpractice claims. In standard medical education, students' communication skills are trained with…

Human-Computer Interaction · Computer Science 2021-04-05 Edoardo Battegazzorre , Andrea Bottino , Fabrizio Lamberti

Evaluating large language models (LLMs) has recently emerged as a critical issue for safe and trustworthy application of LLMs in the medical domain. Although a variety of static medical question-answering (QA) benchmarks have been proposed,…

Computation and Language · Computer Science 2025-12-12 Gyutaek Oh , Sangjoon Park , Byung-Hoon Kim

Artificial intelligence has significantly advanced healthcare, particularly through large language models (LLMs) that excel in medical question answering benchmarks. However, their real-world clinical application remains limited due to the…

Computation and Language · Computer Science 2024-07-01 Zhihao Fan , Jialong Tang , Wei Chen , Siyuan Wang , Zhongyu Wei , Jun Xi , Fei Huang , Jingren Zhou

The process of matching patients with suitable clinical trials is essential for advancing medical research and providing optimal care. However, current approaches face challenges such as data standardization, ethical considerations, and a…

Computation and Language · Computer Science 2023-08-08 Jiayi Yuan , Ruixiang Tang , Xiaoqian Jiang , Xia Hu

Effective patient communication is pivotal in healthcare, yet traditional medical training often lacks exposure to diverse, challenging interpersonal dynamics. To bridge this gap, this study proposes the use of Large Language Models (LLMs)…

Despite advancements in Large Language Models (LLMs) and Large Multimodal Models (LMMs), their integration into language-grounded, human-like embodied agents remains incomplete, hindering complex real-life task performance in physical…

Computation and Language · Computer Science 2024-08-20 Zhili Cheng , Zhitong Wang , Jinyi Hu , Shengding Hu , An Liu , Yuge Tu , Pengkai Li , Lei Shi , Zhiyuan Liu , Maosong Sun

Recent developments in large language models (LLMs) have unlocked new opportunities for healthcare, from information synthesis to clinical decision support. These new LLMs are not just capable of modeling language, but can also act as…

Human-Computer Interaction · Computer Science 2023-09-21 Nikita Mehandru , Brenda Y. Miao , Eduardo Rodriguez Almaraz , Madhumita Sushil , Atul J. Butte , Ahmed Alaa

Large Language Models (LLMs) have demonstrated impressive capabilities in role-playing scenarios, particularly in simulating domain-specific experts using tailored prompts. This ability enables LLMs to adopt the persona of individuals with…

Artificial Intelligence · Computer Science 2025-01-14 Xinyao Ma , Rui Zhu , Zihao Wang , Jingwei Xiong , Qingyu Chen , Haixu Tang , L. Jean Camp , Lucila Ohno-Machado
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