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Calibration$\unicode{x2014}$the problem of ensuring that predicted probabilities align with observed class frequencies$\unicode{x2014}$is a basic desideratum for reliable prediction with machine learning systems. Calibration error is…

Machine Learning · Statistics 2026-03-02 Eugène Berta , Sacha Braun , David Holzmüller , Francis Bach , Michael I. Jordan

Probabilistic classifiers output a probability distribution on target classes rather than just a class prediction. Besides providing a clear separation of prediction and decision making, the main advantage of probabilistic models is their…

Machine Learning · Computer Science 2019-02-20 Juozas Vaicenavicius , David Widmann , Carl Andersson , Fredrik Lindsten , Jacob Roll , Thomas B. Schön

Variant effect predictors (VEPs) aim to assess the functional impact of protein variants, traditionally relying on multiple sequence alignments (MSAs). This approach assumes that naturally occurring variants are fit, an assumption…

Machine Learning · Computer Science 2025-07-04 Antoine Honoré , Borja Rodríguez Gálvez , Yoomi Park , Yitian Zhou , Volker M. Lauschke , Ming Xiao

Event-related potential (ERP), a specialized paradigm of electroencephalographic (EEG), reflects neurological responses to external stimuli or events, generally associated with the brain's processing of specific cognitive tasks. ERP plays a…

Neural and Evolutionary Computing · Computer Science 2026-04-21 Yihe Wang , Zhiqiao Kang , Bohan Chen , Yu Zhang , Xiang Zhang

Vanilla variational inference finds an optimal approximation to the Bayesian posterior distribution, but even the exact Bayesian posterior is often not meaningful under model misspecification. We propose predictive variational inference…

Machine Learning · Statistics 2026-03-31 Jinlin Lai , Antonio Linero , Yuling Yao

When evaluating the efficacy of social programs and medical treatments using randomized experiments, the estimated overall average causal effect alone is often of limited value and the researchers must investigate when the treatments do and…

Applications · Statistics 2013-05-27 Kosuke Imai , Marc Ratkovic

Errors in variables (Deming) regression of measurements spanning a wide range of values requires appropriate weighting to reflect nonconstant variance. Precision profile models, mathematical relationships between measurement variance and…

Computation · Statistics 2025-08-06 Douglas M Hawkins , Jessica J Kraker

The deployment of machine learning classifiers in high-stakes domains requires well-calibrated confidence scores for model predictions. In this paper we introduce the notion of variable-based calibration to characterize calibration…

Machine Learning · Computer Science 2023-04-07 Markelle Kelly , Padhraic Smyth

The propensity score is widely used for causal inference in observational studies, but common parametric estimators can produce biased and inefficient effect estimates when model assumptions are violated. Nonparametric approaches reduce…

Methodology · Statistics 2026-04-09 Maosen Peng , Yan Li , Chong Wu , Liang Li

This paper presents a novel online identification algorithm for nonlinear regression models. The online identification problem is challenging due to the presence of nonlinear structure in the models. Previous works usually ignore the…

Optimization and Control · Mathematics 2022-07-21 Guang-Yong Chen , Min Gan , Jing Chen , Long Chen

Performance variability is an important measure for a reliable high performance computing (HPC) system. Performance variability is affected by complicated interactions between numerous factors, such as CPU frequency, the number of…

Distributed, Parallel, and Cluster Computing · Computer Science 2020-12-16 Li Xu , Thomas Lux , Tyler Chang , Bo Li , Yili Hong , Layne Watson , Ali Butt , Danfeng Yao , Kirk Cameron

In recent studies on model-based reinforcement learning (MBRL), incorporating uncertainty in forward dynamics is a state-of-the-art strategy to enhance learning performance, making MBRLs competitive to cutting-edge model free methods,…

Machine Learning · Computer Science 2019-10-08 Masashi Okada , Tadahiro Taniguchi

While deep neural networks are highly performant and successful in a wide range of real-world problems, estimating their predictive uncertainty remains a challenging task. To address this challenge, we propose and implement a loss function…

Machine Learning · Computer Science 2022-10-14 Tony Tohme , Kevin Vanslette , Kamal Youcef-Toumi

Computer simulations have proven a valuable tool for understanding complex phenomena across the sciences. However, the utility of simulators for modelling and forecasting purposes is often restricted by low data quality, as well as…

Machine Learning · Statistics 2022-10-14 Daniel Ward , Patrick Cannon , Mark Beaumont , Matteo Fasiolo , Sebastian M Schmon

This paper provides a new methodology to analyze unobserved heterogeneity when observed characteristics are modeled nonlinearly. The proposed model builds on varying random coefficients (VRC) that are determined by nonlinear functions of…

Econometrics · Economics 2020-08-05 Christoph Breunig

Experimentation platforms in industry must often deal with customer trust issues. Platforms must prove the validity of their claims as well as catch issues that arise. As a central quantity estimated by experimentation platforms, the…

Methodology · Statistics 2025-11-21 Kedar Karhadkar , Jack Klys , Daniel Ting , Artem Vorozhtsov , Houssam Nassif

The predictiveness curve is a valuable tool for predictive evaluation, risk stratification, and threshold selection in a target population, given a single biomarker or a prediction model. In the presence of competing risks, regression…

Methodology · Statistics 2025-08-04 Wei Tao , Jing Ning , Wen Li , Wenyaw Chan , Xi Luo , Ruosha Li

As an important problem in causal inference, we discuss the identification and estimation of treatment effects (TEs) under limited overlap; that is, when subjects with certain features belong to a single treatment group. We use a latent…

Machine Learning · Statistics 2022-04-22 Pengzhou Wu , Kenji Fukumizu

Deep neural networks have achieved impressive results on a wide variety of tasks. However, quantifying uncertainty in the network's output is a challenging task. Bayesian models offer a mathematical framework to reason about model…

Machine Learning · Computer Science 2019-05-28 Manikanta Srikar Yellapragada , Chandra Prakash Konkimalla

Effective reinforcement learning (RL) for complex stochastic systems requires leveraging historical data collected in previous iterations to accelerate policy optimization. Classical experience replay treats all past observations uniformly…

Machine Learning · Statistics 2026-02-06 Hua Zheng , Wei Xie , M. Ben Feng , Keilung Choy