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Previous work on causal inference has primarily focused on averages and conditional averages of treatment effects, with significantly less attention on variability and uncertainty in individual treatment responses. In this paper, we…

Machine Learning · Computer Science 2026-02-10 Liyuan Xu , Bijan Mazaheri

In practical regression applications, multiple covariates are often measured, but not all may be associated with the response variable. Identifying and including only the relevant covariates in the model is crucial for improving prediction…

Methodology · Statistics 2026-03-10 Ana Carolina da Cruz , Camila P. E. de Souza , Pedro H. T. O. Sousa

In recent years, various kernels have been proposed in the context of persistent homology to deal with persistence diagrams in supervised learning approaches. In this paper, we consider the idea of variably scaled kernels, for approximating…

Numerical Analysis · Mathematics 2022-02-22 Stefano De Marchi , Federico Lot , Francesco Marchetti , Davide Poggiali

Missing data is a common challenge in biomedical research. This fact, along with growing dataset volumes of the modern era, make the issue of computationally-efficient analysis with missing data of crucial practical importance. A general…

Methodology · Statistics 2022-04-22 Giorgos Bakoyannis , Philani B. Mpofu , Andrea Broyles , Brian B. Dixon

In this paper, we propose Varying Effects Regression with Graph Estimation (VERGE), a novel Bayesian method for feature selection in regression. Our model has key aspects that allow it to leverage the complex structure of data sets arising…

Methodology · Statistics 2024-10-10 Yangfan Ren , Christine B. Peterson , Marina Vannucci

This paper investigates the sensitivity of forecast performance measures to taking a real time versus pseudo out-of-sample perspective. We use monthly vintages for the United States (US) and the Euro Area (EA) and estimate a set of vector…

Econometrics · Economics 2020-04-13 Michael Pfarrhofer

Existing regression models tend to fall short in both accuracy and uncertainty estimation when the label distribution is imbalanced. In this paper, we propose a probabilistic deep learning model, dubbed variational imbalanced regression…

Machine Learning · Computer Science 2024-11-12 Ziyan Wang , Hao Wang

We present two deep generative models based on Variational Autoencoders to improve the accuracy of drug response prediction. Our models, Perturbation Variational Autoencoder and its semi-supervised extension, Drug Response Variational…

Machine Learning · Statistics 2017-07-07 Ladislav Rampasek , Daniel Hidru , Petr Smirnov , Benjamin Haibe-Kains , Anna Goldenberg

For reinforcement learning on complex stochastic systems where many factors dynamically impact the output trajectories, it is desirable to effectively leverage the information from historical samples collected in previous iterations to…

Machine Learning · Statistics 2022-09-13 Hua Zheng , Wei Xie , M. Ben Feng

Process variant analysis aims at identifying and addressing the differences existing in a set of process executions enacted by the same process model. A process model can be executed differently in different situations for various reasons,…

Other Computer Science · Computer Science 2019-12-24 Farbod Taymouri , Marcello La Rosa , Marlon Dumas , Fabrizio Maria Maggi

We present a priori and a posteriori error analysis of a Virtual Element Method (VEM) to approximate the vibration frequencies and modes of an elastic solid. We analyze a variational formulation relying only on the solid displacement and…

Numerical Analysis · Mathematics 2017-12-20 David Mora , Gonzalo Rivera

Causal inference is to estimate the causal effect in a causal relationship when intervention is applied. Precisely, in a causal model with binary interventions, i.e., control and treatment, the causal effect is simply the difference between…

Machine Learning · Computer Science 2022-07-19 Zhenyu Lu , Yurong Cheng , Mingjun Zhong , George Stoian , Ye Yuan , Guoren Wang

Virtual cell (VC) models aim to predict cellular responses to any perturbations in silico and have emerged as a promising approach for drug discovery and precision medicine. Yet, a clear gap still remains: while models routinely reported…

Cell Behavior · Quantitative Biology 2026-05-01 Xinjie Mao , Songming Zhang , Qianhong Wen , Xiangyu Wen , Kedu Jin , Hao Wu , Shuizhou Chen , Yuqiang Li , Lei Bai , Qi Liu , Ning Ding , Siqi Sun , Zhangyang Gao

Virtual experiments (VEs), a modern tool in metrology, can be used to help perform an uncertainty evaluation for the measurand. Current guidelines in metrology do not cover the many possibilities to incorporate VEs into an uncertainty…

Applications · Statistics 2024-04-18 Finn Hughes , Manuel Marschall , Gerd Wübbeler , Gertjan Kok , Marcel van Dijk , Clemens Elster

For some classification scenarios, it is desirable to use only those classification instances that a trained model associates with a high certainty. To obtain such high-certainty instances, previous work has proposed accuracy-reject curves.…

Machine Learning · Computer Science 2024-03-15 Lydia Fischer , Patricia Wollstadt

Developing tools for estimating heterogeneous treatment effects (HTE) and individualized treatment effects has been an area of active research in recent years. While these tools have proven to be useful in many contexts, a concern when…

Methodology · Statistics 2025-03-07 Mahsa Ashouri , Nicholas C. Henderson

Recent work on reinforcement learning with verifiable rewards (RLVR) has shown that large language models (LLMs) can be substantially improved using outcome-level verification signals, such as unit tests for code or exact-match checks for…

Computation and Language · Computer Science 2026-01-27 Massimiliano Pronesti , Anya Belz , Yufang Hou

Ensembling is now recognized as an effective approach for increasing the predictive performance and calibration of deep networks. We introduce a new approach, Parameter Ensembling by Perturbation (PEP), that constructs an ensemble of…

Machine Learning · Computer Science 2020-10-27 Alireza Mehrtash , Purang Abolmaesumi , Polina Golland , Tina Kapur , Demian Wassermann , William M. Wells

Inference networks of traditional Variational Autoencoders (VAEs) are typically amortized, resulting in relatively inaccurate posterior approximation compared to instance-wise variational optimization. Recent semi-amortized approaches were…

Machine Learning · Computer Science 2020-11-18 Minyoung Kim , Vladimir Pavlovic

The motivations for using variational inference (VI) in neural networks differ significantly from those in latent variable models. This has a counter-intuitive consequence; more expressive variational approximations can provide…

Machine Learning · Statistics 2018-01-22 Brian Trippe , Richard Turner