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In this review paper, we delve into the nascent field of molecular data storage, focusing on system implementations and code constructions. We start by providing an overview of basic concepts in synthetic and computational biology.…

Emerging Technologies · Computer Science 2023-10-10 Olgica Milenkovic , Chao Pan

One of the most important and challenging problems in coding theory is to determine the optimal values of the parameters of a linear code and to explicitly construct codes with optimal parameters, or as close to the optimal values as…

Information Theory · Computer Science 2021-06-25 Nuh Aydin , Thomas Guidotti , Peihan Liu

Sequencing a genome to determine an individual's DNA produces an enormous number of short nucleotide subsequences known as reads, which must be reassembled to reconstruct the full genome. We present a method for analyzing this type of data…

Machine Learning · Computer Science 2025-05-23 Filip Thor , Carl Nettelblad

Let $\mathbb F_q$ be a finite field, where $q$ is an odd prime power. Let $R=\mathbb{F}_q+u\mathbb{F}_q+v\mathbb{F}_q+uv\mathbb F_q$ with $u^2=u,v^2=v,uv=vu$. In this paper, we study the algebraic structure of $(\theta, \Theta)$-cyclic…

Information Theory · Computer Science 2024-04-02 Awadhesh Kumar Shukla , Sachin Pathak , Om Prakash Pandey , Vipul Mishra , Ashish Kumar Upadhyay

Recent genomic foundation models largely adopt large language model architectures that treat DNA as a one-dimensional token sequence. However, exhaustive sequential reading is structurally misaligned with sparse and discontinuous genomic…

Computer Vision and Pattern Recognition · Computer Science 2026-02-03 Hongxin Xiang , Pengsen Ma , Yunkang Cao , Di Yu , Haowen Chen , Xinyu Yang , Xiangxiang Zeng

Let $R=\mathbb{Z}_{4}[u]/\langle u^k\rangle=\mathbb{Z}_{4}+u\mathbb{Z}_{4}+\ldots+u^{k-1}\mathbb{Z}_{4}$ ($u^k=0$) where $k\in \mathbb{Z}^{+}$ satisfies $k\geq 2$. For any odd positive integer $n$, it is known that cyclic codes over $R$ of…

Information Theory · Computer Science 2016-06-17 Cao Yuan , Li Qingguo

Biomolecular computation has emerged as an important area of computer science research due to its high information density, immense parallelism opportunity along with potential applications in cryptography, genetic engineering and…

Formal Languages and Automata Theory · Computer Science 2022-06-07 Anupam Chattopadhyay , Arnab Chakrabarti

Let $\mathcal{R}_{e,m}$ be a finite commutative chain ring of even characteristic with maximal ideal $\langle u \rangle$ of nilpotency index $e \geq 2,$ Teichm$\ddot{u}$ller set $\mathcal{T}_{m},$ and residue field…

Information Theory · Computer Science 2026-01-16 Monika Yadav , Anuradha Sharma

Enzymatic DNA labeling is a powerful tool with applications in biochemistry, molecular biology, biotechnology, medical science, and genomic research. This paper contributes to the evolving field of DNA-based data storage by presenting a…

Information Theory · Computer Science 2024-05-15 Daniella Bar-Lev , Tuvi Etzion , Eitan Yaakobi , Zohar Yakhini

This paper introduces a new solution to DNA storage that integrates all three steps of retrieval, namely clustering, reconstruction, and error correction. DNA-correcting codes are presented as a unique solution to the problem of ensuring…

Information Theory · Computer Science 2024-07-02 Avital Boruchovsky , Daniella Bar-Lev , Eitan Yaakobi

In this article, we construct infinite families of quaternary (that is, over the ring $\mathbb{Z}_4$) $\mathcal{C}_{D}$-codes, where the defining set $D$ is derived utilizing a two-generator simplicial complex, and determine their Lee…

Information Theory · Computer Science 2026-05-15 Ankit Yadav , Nilay Kumar Mondal , Ritumoni Sarma

In this paper, we shall give an explicit proof that constacyclic codes over finite commutative rings can be realized as ideals in some twisted group rings. Also, we shall study isometries between those codes and, finally, we shall study…

Information Theory · Computer Science 2023-07-26 Samir Assuena

There are exactly two non-commutative rings of size $4$, namely, $E = \langle a, b ~\vert ~ 2a = 2b = 0, a^2 = a, b^2 = b, ab= a, ba = b\rangle$ and its opposite ring $F$. These rings are non-unital. A subset $D$ of $E^m$ is defined with…

Information Theory · Computer Science 2023-09-20 Vidya Sagar , Ritumoni Sarma

DNA data storage systems encode digital data into DNA strands, enabling dense and durable storage. Efficient data retrieval depends on coverage depth, a key performance metric. We study the random access coverage depth problem and focus on…

Information Theory · Computer Science 2025-07-29 Şeyma Bodur , Stefano Lia , Hiram H. López , Rati Ludhani , Alberto Ravagnani , Lisa Seccia

Based on the generic construction of linear codes, we construct linear codes over the ring $\Bbb Z_4$ via posets of the disjoint union of two chains. We determine the Lee weight distributions of the quaternary codes. Moreover, we obtain…

Information Theory · Computer Science 2019-10-29 Xiaomeng Zhu , Yansheng Wu , Qin Yue

Fabrication of DNA nanostructures primarily follows two fundamental rules. First, DNA oligonucleotides mutually combine by Watson-Crick base pairing rules between complementary base sequences. Second, the geometrical compatibility of the…

Mesoscale and Nanoscale Physics · Physics 2011-06-01 Jihoon Shin , Junghoon Kim , Rashid Amin , Seungjae Kim , Young Hun Kwon , Sung Ha Park

We consider the problem of coding for the substring channel, in which information strings are observed only through their (multisets of) substrings. Due to existing DNA sequencing techniques and applications in DNA-based storage systems,…

Information Theory · Computer Science 2024-03-27 Yonatan Yehezkeally , Nikita Polyanskii

A novel code construction algorithm is presented to find all the possible code families for code reconfiguration in an OCDMA system. The algorithm is developed through searching all the complete subgraphs of a constructed graph. The…

Information Theory · Computer Science 2007-07-13 Xiang Lu , Jiajia Chen , Sailing He

This study explores the self-synchronization problem in DNA coding, specifically addressing single-deletion errors without using delimiters between codewords. We aim to identify the beginning of each codeword without using delimiters,…

Information Theory · Computer Science 2026-03-31 Whan-Hyuk Choi

We study constacyclic codes, of length $np^s$ and $2np^s$, that are generated by the polynomials $(x^n + \gamma)^{\ell}$ and $(x^n - \xi)^i(x^n + \xi)^j$\ respectively, where $x^n + \gamma$, $x^n - \xi$ and $x^n + \xi$ are irreducible over…

Information Theory · Computer Science 2009-06-23 Hakan Ozadam , Ferruh Ozbudak
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