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We propose an efficient evaluation protocol for large vision-language models (VLMs). Given their broad knowledge and reasoning capabilities, multiple benchmarks are needed for comprehensive assessment, making evaluation computationally…

Computer Vision and Pattern Recognition · Computer Science 2025-04-15 Teppei Suzuki , Keisuke Ozawa

Nucleus detection in histopathology whole slide images (WSIs) is crucial for a broad spectrum of clinical applications. The gigapixel size of WSIs necessitates the use of sliding window methodology for nucleus detection. However, mainstream…

Image and Video Processing · Electrical Eng. & Systems 2026-02-10 Zhongyi Shui , Honglin Li , Yunlong Zhang , Yuxuan Sun , Yiwen Ye , Pingyi Chen , Ruizhe Guo , Lei Cui , Chenglu Zhu , Lin Yang

Accurate prediction of placental diseases via whole slide images (WSIs) is critical for preventing severe maternal and fetal complications. However, WSI analysis presents significant computational challenges due to the massive data volume.…

Computer Vision and Pattern Recognition · Computer Science 2025-08-06 Hang Guo , Qing Zhang , Zixuan Gao , Siyuan Yang , Shulin Peng , Xiang Tao , Ting Yu , Yan Wang , Qingli Li

It is well-established that more data generally improves AI model performance. However, data collection can be challenging for certain tasks due to the rarity of occurrences or high costs. These challenges are evident in our use case, where…

Computer Vision and Pattern Recognition · Computer Science 2025-09-17 Martin Thißen , Thi Ngoc Diep Tran , Barbara Esteve Ratsch , Ben Joel Schönbein , Ute Trapp , Beate Egner , Romana Piat , Elke Hergenröther

Prompt learning has emerged as a promising paradigm for adapting pre-trained vision-language models (VLMs) to few-shot whole slide image (WSI) classification by aligning visual features with textual representations, thereby reducing…

Computer Vision and Pattern Recognition · Computer Science 2025-10-01 Junjie Zhou , Wei Shao , Yagao Yue , Wei Mu , Peng Wan , Qi Zhu , Daoqiang Zhang

Accurate and early diagnosis of malignant melanoma is critical for improving patient outcomes. While convolutional neural networks (CNNs) have shown promise in dermoscopic image analysis, they often neglect clinical metadata and require…

Computer Vision and Pattern Recognition · Computer Science 2025-09-11 Jihyun Moon , Charmgil Hong

Recent advances in multimodal large language models enable new possibilities for image-based decision support. However, their reliability and operational trade-offs in neuroimaging remain insufficiently understood. We present a…

Computer Vision and Pattern Recognition · Computer Science 2026-03-27 Katarina Trojachanec Dineva , Stefan Andonov , Ilinka Ivanoska , Ivan Kitanovski , Sasho Gramatikov , Tamara Kostova , Monika Simjanoska Misheva , Kostadin Mishev

Computational pathology, which involves analyzing whole slide images for automated cancer diagnosis, relies on multiple instance learning, where performance depends heavily on the feature extractor and aggregator. Recent Pathology…

Computer Vision and Pattern Recognition · Computer Science 2025-05-22 Conghao Xiong , Hao Chen , Joseph J. Y. Sung

Large Vision-Language Models (LVLMs) have shown impressive capabilities across a range of tasks that integrate visual and textual understanding, such as image captioning and visual question answering. These models are trained on large-scale…

Computer Vision and Pattern Recognition · Computer Science 2026-03-11 Xiaomei Zhang , Hanyu Zheng , Xiangyu Zhu , Jinghuan Wei , Junhong Zou , Zhen Lei , Zhaoxiang Zhang

Whole Slide Image (WSI) MLLMs are difficult to build and deploy because gigapixel slides induce thousands of visual tokens, while only a small fraction of regions is diagnostically relevant. Existing slide-level pathology MLLMs typically…

Computer Vision and Pattern Recognition · Computer Science 2026-03-13 Qingqiao Hu , Weimin Lyu , Meilong Xu , Kehan Qi , Xiaoling Hu , Saumya Gupta , Jiawei Zhou , Chao Chen

Despite the progress made by multimodal large language models (MLLMs) in computational pathology, they remain limited by a predominant focus on patch-level analysis, missing essential contextual information at the whole-slide level. The…

Computer Vision and Pattern Recognition · Computer Science 2025-03-20 Ying Chen , Guoan Wang , Yuanfeng Ji , Yanjun Li , Jin Ye , Tianbin Li , Ming Hu , Rongshan Yu , Yu Qiao , Junjun He

Large language models (LLMs) are increasingly used to extract structured information from free-text clinical records, but prior work often focuses on single tasks, limited models, and English-language reports. We evaluated 15 open-weight…

We investigate fine-tuning Vision-Language Models (VLMs) for multi-task medical image understanding, focusing on detection, localization, and counting of findings in medical images. Our objective is to evaluate whether instruction-tuned…

Computer Vision and Pattern Recognition · Computer Science 2025-09-03 Sushant Gautam , Michael A. Riegler , Pål Halvorsen

This research introduces a transformative framework for integrating Vision-Enhanced Large Language Models (LLMs) with advanced transformer-based architectures to tackle challenges in high-resolution image synthesis and multimodal data…

Computer Vision and Pattern Recognition · Computer Science 2026-01-06 Karthikeya KV

The prevalence of vision-threatening eye diseases is a significant global burden, with many cases remaining undiagnosed or diagnosed too late for effective treatment. Large vision-language models (LVLMs) have the potential to assist in…

Computer Vision and Pattern Recognition · Computer Science 2025-02-06 Zhenyue Qin , Yu Yin , Dylan Campbell , Xuansheng Wu , Ke Zou , Yih-Chung Tham , Ninghao Liu , Xiuzhen Zhang , Qingyu Chen

Hepatocellular Carcinoma diagnosis relies heavily on the interpretation of gigapixel Whole Slide Images. However, current computational approaches are constrained by fixed-resolution processing mechanisms and inefficient feature…

Computer Vision and Pattern Recognition · Computer Science 2026-03-03 Yuxuan Yang , Zhonghao Yan , Yi Zhang , Bo Yun , Muxi Diao , Guowei Zhao , Kongming Liang , Wenbin Li , Zhanyu Ma

Multimodal large models have shown great potential in automating pathology image analysis. However, current multimodal models for gastrointestinal pathology are constrained by both data quality and reasoning transparency: pervasive noise…

Image and Video Processing · Electrical Eng. & Systems 2025-07-25 Minxi Ouyang , Lianghui Zhu , Yaqing Bao , Qiang Huang , Jingli Ouyang , Tian Guan , Xitong Ling , Jiawen Li , Song Duan , Wenbin Dai , Li Zheng , Xuemei Zhang , Yonghong He

In-context learning (ICL) with Large Vision Models (LVMs) presents a promising avenue in medical image segmentation by reducing the reliance on extensive labeling. However, the ICL performance of LVMs highly depends on the choices of visual…

Computer Vision and Pattern Recognition · Computer Science 2024-07-17 Chenwei Wu , David Restrepo , Zitao Shuai , Zhongming Liu , Liyue Shen

Large language models (LLMs) show promise for extracting clinically meaningful information from unstructured health records, yet their translation into real-world settings is constrained by the lack of scalable and trustworthy validation…

Vision-threatening eye diseases pose a major global health burden, with timely diagnosis limited by workforce shortages and restricted access to specialized care. While multimodal large language models (MLLMs) show promise for medical image…