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Medical image diagnosis is challenging because many diseases resemble normal anatomy and exhibit substantial interpatient variability. Clinicians routinely rely on comparative diagnosis, such as referencing cross-patient healthy control…

Computer Vision and Pattern Recognition · Computer Science 2026-02-24 Ruinan Jin , Gexin Huang , Xinwei Shen , Qiong Zhang , Yan Shuo Tan , Xiaoxiao Li

Large Language Models (LLMs) have shown significant promise across various natural language processing tasks. However, their application in the field of pathology, particularly for extracting meaningful insights from unstructured medical…

Computation and Language · Computer Science 2025-03-04 Rachit Saluja , Jacob Rosenthal , Yoav Artzi , David J. Pisapia , Benjamin L. Liechty , Mert R. Sabuncu

Lane topology extraction involves detecting lanes and traffic elements and determining their relationships, a key perception task for mapless autonomous driving. This task requires complex reasoning, such as determining whether it is…

Computer Vision and Pattern Recognition · Computer Science 2025-03-11 Zongzheng Zhang , Xinrun Li , Sizhe Zou , Guoxuan Chi , Siqi Li , Xuchong Qiu , Guoliang Wang , Guantian Zheng , Leichen Wang , Hang Zhao , Hao Zhao

Vision language models (VLM) have demonstrated remarkable performance across various downstream tasks. However, understanding fine-grained visual-linguistic concepts, such as attributes and inter-object relationships, remains a significant…

Computer Vision and Pattern Recognition · Computer Science 2024-04-02 Wujian Peng , Sicheng Xie , Zuyao You , Shiyi Lan , Zuxuan Wu

Recent advancements in Large Vision-Language Models (LVLMs) have demonstrated remarkable multimodal perception capabilities, garnering significant attention. While numerous evaluation studies have emerged, assessing LVLMs both holistically…

Computer Vision and Pattern Recognition · Computer Science 2026-05-01 Hong-Tao Yu , Yuxin Peng , Serge Belongie , Xiu-Shen Wei

Various multi-instance learning (MIL) based approaches have been developed and successfully applied to whole-slide pathological images (WSI). Existing MIL methods emphasize the importance of feature aggregators, but largely neglect the…

Computer Vision and Pattern Recognition · Computer Science 2025-05-13 Yicheng Song , Tiancheng Lin , Die Peng , Su Yang , Yi Xu

Tumor segmentation stands as a pivotal task in cancer diagnosis. Given the immense dimensions of whole slide images (WSI) in histology, deep learning approaches for WSI classification mainly operate at patch-wise or superpixel-wise level.…

Computer Vision and Pattern Recognition · Computer Science 2024-02-22 Huaqian Wu , Clara Brémond-Martin , Kévin Bouaou , Cédric Clouchoux

The extraction of lung lesion information from clinical and medical imaging reports is crucial for research on and clinical care of lung-related diseases. Large language models (LLMs) can be effective at interpreting unstructured text in…

Computation and Language · Computer Science 2024-11-18 Diya Li , Asim Kadav , Aijing Gao , Rui Li , Richard Bourgon

The emergence of tool-calling-based agent systems introduces a more evidence-driven paradigm for pathology image analysis in contrast to the coarse-grained text-image diagnostic approaches. With the recent large-scale experimental adoption…

Artificial Intelligence · Computer Science 2026-02-24 Haoyang Su , Shaoting Zhang , Xiaosong Wang

Artificial intelligence (AI) shows great potential in assisting radiologists to improve the efficiency and accuracy of medical image interpretation and diagnosis. However, a versatile AI model requires large-scale data and comprehensive…

Computer Vision and Pattern Recognition · Computer Science 2025-01-27 Zhongyi Shui , Jianpeng Zhang , Weiwei Cao , Sinuo Wang , Ruizhe Guo , Le Lu , Lin Yang , Xianghua Ye , Tingbo Liang , Qi Zhang , Ling Zhang

In computational pathology, multiple instance learning (MIL) is widely used to circumvent the computational impasse in giga-pixel whole slide image (WSI) analysis. It usually consists of two stages: patch-level feature extraction and…

Image and Video Processing · Electrical Eng. & Systems 2023-09-21 Beidi Zhao , Wenlong Deng , Zi Han , Li , Chen Zhou , Zuhua Gao , Gang Wang , Xiaoxiao Li

Large language models (LLMs) are effective at capturing complex, valuable conceptual representations from textual data for a wide range of real-world applications. However, in fields like Intelligent Fault Diagnosis (IFD), incorporating…

Artificial Intelligence · Computer Science 2024-12-03 Hamzah A. A. M. Qaid , Bo Zhang , Dan Li , See-Kiong Ng , Wei Li

Digital whole-slide images of pathological tissue samples have recently become feasible for use within routine diagnostic practice. These gigapixel sized images enable pathologists to perform reviews using computer workstations instead of…

Human-Computer Interaction · Computer Science 2016-10-14 Jesper Molin , Anna Bodén , Darren Treanor , Morten Fjeld , Claes Lundström

Although Vision Language Models (VLMs) have shown strong generalization in medical imaging, pathology presents unique challenges due to ultra-high resolution, complex tissue structures, and nuanced clinical semantics. These factors make…

Computer Vision and Pattern Recognition · Computer Science 2026-03-24 Wenchuan Zhang , Jingru Guo , Hengzhe Zhang , Penghao Zhang , Jie Chen , Shuwan Zhang , Zhang Zhang , Yuhao Yi , Hong Bu

The use of Large Language Models (LLMs) has drawn growing interest within the scientific community. LLMs can handle large volumes of textual data and support methods for evidence synthesis. Although recent studies highlight the potential of…

Software Engineering · Computer Science 2026-02-12 Cauã Ferreira Barros , Marcos Kalinowski , Mohamad Kassab , Valdemar Vicente Graciano Neto

This paper introduces an approach that combines the language reasoning capabilities of large language models (LLMs) with the benefits of local training to tackle complex, domain-specific tasks. Specifically, the authors demonstrate their…

Computation and Language · Computer Science 2023-08-04 V. K. Cody Bumgardner , Aaron Mullen , Sam Armstrong , Caylin Hickey , Jeff Talbert

Large-scale Vision Language Models (LVLMs) exhibit advanced capabilities in tasks that require visual information, including object detection. These capabilities have promising applications in various industrial domains, such as autonomous…

Computer Vision and Pattern Recognition · Computer Science 2025-12-01 Haruki Sakajo , Hiroshi Takato , Hiroshi Tsutsui , Komei Soda , Hidetaka Kamigaito , Taro Watanabe

Whole-slide image (WSI) preprocessing, comprising tissue detection followed by patch extraction, is foundational to AI-driven computational pathology but remains a major bottleneck for scaling to large and heterogeneous cohorts. We present…

Large Language Models (LLMs) have rapidly become important tools in Biomedical and Health Informatics (BHI), enabling new ways to analyze data, treat patients, and conduct research. This study aims to provide a comprehensive overview of LLM…

Digital Libraries · Computer Science 2024-07-30 Huizi Yu , Lizhou Fan , Lingyao Li , Jiayan Zhou , Zihui Ma , Lu Xian , Wenyue Hua , Sijia He , Mingyu Jin , Yongfeng Zhang , Ashvin Gandhi , Xin Ma

Large language models (LLMs) are increasingly used to extract clinical data from electronic health records (EHRs), offering significant improvements in scalability and efficiency for real-world data (RWD) curation in oncology. However, the…

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