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In this work, we consider the problem of predicting the course of a progressive disease, such as cancer or Alzheimer's. Progressive diseases often start with mild symptoms that might precede a diagnosis, and each patient follows their own…

Machine Learning · Computer Science 2018-03-19 Yingying Zhu , Mert R. Sabuncu

Multivariate time series forecasting focuses on predicting future values based on historical context. State-of-the-art sequence-to-sequence models rely on neural attention between timesteps, which allows for temporal learning but fails to…

Machine Learning · Computer Science 2023-03-21 Jake Grigsby , Zhe Wang , Nam Nguyen , Yanjun Qi

The adoption of electronic health records (EHR) has become universal during the past decade, which has afforded in-depth data-based research. By learning from the large amount of healthcare data, various data-driven models have been built…

Machine Learning · Computer Science 2021-06-25 Xianlong Zeng , Simon Lin , Chang Liu

Foundation models in healthcare have largely adopted self supervised pretraining objectives inherited from natural language processing and computer vision, emphasizing reconstruction and large scale representation learning prior to…

Machine Learning · Computer Science 2026-03-24 Yang Zhang , Li Fan , Samuel Lawrence , Shi Li

Given the growing complexity of healthcare data over the last several years, using machine learning techniques like Deep Neural Network (DNN) models has gained increased appeal. In order to extract hidden patterns and other valuable…

Machine Learning · Computer Science 2023-10-03 Hasan Hejbari Zargar , Saha Hejbari Zargar , Raziye Mehri

Human intention prediction is a growing area of research where an activity in a video has to be anticipated by a vision-based system. To this end, the model creates a representation of the past, and subsequently, it produces future…

Computer Vision and Pattern Recognition · Computer Science 2022-10-27 Nada Osman , Guglielmo Camporese , Lamberto Ballan

Accurately predicting the dynamics of robotic systems is crucial for model-based control and reinforcement learning. The most common way to estimate dynamics is by fitting a one-step ahead prediction model and using it to recursively…

Machine Learning · Computer Science 2021-09-02 Nathan O. Lambert , Albert Wilcox , Howard Zhang , Kristofer S. J. Pister , Roberto Calandra

Clinical trials are a systematic endeavor to assess the safety and efficacy of new drugs or treatments. Conducting such trials typically demands significant financial investment and meticulous planning, highlighting the need for accurate…

Machine Learning · Computer Science 2025-11-03 Tien Huu Do , Antoine Masquelier , Nae Eoun Lee , Jonathan Crowther

Disease progression modeling provides a robust framework to identify long-term disease trajectories from short-term biomarker data. It is a valuable tool to gain a deeper understanding of diseases with a long disease trajectory, such as…

Transformer is a deep neural network that employs a self-attention mechanism to comprehend the contextual relationships within sequential data. Unlike conventional neural networks or updated versions of Recurrent Neural Networks (RNNs) such…

Machine Learning · Computer Science 2023-06-14 Saidul Islam , Hanae Elmekki , Ahmed Elsebai , Jamal Bentahar , Najat Drawel , Gaith Rjoub , Witold Pedrycz

With U.S. healthcare spending approaching $5T (NHE Fact Sheet 2024), and 25% of it estimated to be wasteful (Waste in the US the health care system: estimated costs and potential for savings, n.d.), the need to better predict risk and…

Machine Learning · Computer Science 2024-12-06 Ricky Sahu , Eric Marriott , Ethan Siegel , David Wagner , Flore Uzan , Troy Yang , Asim Javed

Transformer models have consistently achieved remarkable results in various domains such as natural language processing and computer vision. However, despite ongoing research efforts to better understand these models, the field still lacks…

Machine Learning · Computer Science 2024-10-18 Ilya Kaufman , Omri Azencot

Healthcare data now span EHRs, medical imaging, genomics, and wearable sensors, but most diagnostic models still process these modalities in isolation. This limits their ability to capture early, cross-modal disease signatures. This paper…

Machine Learning · Computer Science 2025-12-18 Md Talha Mohsin , Ismail Abdulrashid

We propose a novel approach to data-driven modeling of a transient production of oil wells. We apply the transformer-based neural networks trained on the multivariate time series composed of various parameters of oil wells measured during…

Machine Learning · Computer Science 2021-10-13 Ildar Abdrakhmanov , Evgenii Kanin , Sergei Boronin , Evgeny Burnaev , Andrei Osiptsov

Predicting upcoming events is critical to our ability to interact with our environment. Transformer models, trained on next-word prediction, appear to construct representations of linguistic input that can support diverse downstream tasks.…

Computation and Language · Computer Science 2023-11-10 Eghbal A. Hosseini , Evelina Fedorenko

Deep learning models, particularly Transformers, have achieved impressive results in various domains, including time series forecasting. While existing time series literature primarily focuses on model architecture modifications and data…

Machine Learning · Computer Science 2023-12-01 Valentino Assandri , Sam Heshmati , Burhaneddin Yaman , Anton Iakovlev , Ariel Emiliano Repetur

The paper presents a novel deep learning approach, which extracts latent information from trained Deep Neural Networks (DNNs) and derives concise representations that are analyzed in an effective, unified way for prediction purposes. It is…

Machine Learning · Computer Science 2020-09-22 D. Kollias , N. Bouas , Y. Vlaxos , V. Brillakis , M. Seferis , I. Kollia , L. Sukissian , J. Wingate , S. Kollias

In this paper, we propose a deep generative time series approach using latent temporal processes for modeling and holistically analyzing complex disease trajectories. We aim to find meaningful temporal latent representations of an…

Predicting whether a treatment leads to meaningful improvement is a central challenge in personalized medicine, particularly when disease progression manifests as subtle visual changes over time. While data-driven deep learning (DL) offers…

Image and Video Processing · Electrical Eng. & Systems 2025-11-21 Jana Armouti , Nikhil Madaan , Rohan Panda , Tom Fox , Laura Hutchins , Amita Krishnan , Ricardo Rodriguez , Bennett DeBoisblanc , Deva Ramanan , John Galeotti , Gautam Gare

Transformer-based large language models have remarkable potential to accelerate design optimization for applications such as drug development and materials discovery. Self-supervised pretraining of transformer models requires large-scale…

Machine Learning · Computer Science 2023-10-27 Pei Zhang , Logan Kearney , Debsindhu Bhowmik , Zachary Fox , Amit K. Naskar , John Gounley
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