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Motivated by the problem of computer-aided detection (CAD) of pulmonary nodules, we introduce methods to propagate and fuse uncertainty information in a multi-stage Bayesian convolutional neural network (CNN) architecture. The question we…

Computer Vision and Pattern Recognition · Computer Science 2018-02-15 Onur Ozdemir , Benjamin Woodward , Andrew A. Berlin

Accurate prediction of molecular vibrational frequencies is important to identify spectroscopic signatures and reaction thermodynamics. In this work, we develop a method to quantify uncertainty associated with density functional theory…

Chemical Physics · Physics 2019-03-13 Holden L. Parks , Alan. J. H. McGaughey , Venkatasubramanian Viswanathan

In this study, we develop a probabilistic approach to map the parametric uncertainty to the output state uncertainty in first-order hyperbolic conservation laws. We analyze this problem for nonlinear immiscible two-phase transport in…

Computational Physics · Physics 2021-05-11 Farzaneh Rajabi , Hamdi A. Tchelepi

Accurate trajectory prediction is crucial for autonomous driving, yet uncertainty in agent behavior and perception noise makes it inherently challenging. While multi-modal trajectory prediction models generate multiple plausible future…

Robotics · Computer Science 2025-03-10 Sajad Marvi , Christoph Rist , Julian Schmidt , Julian Jordan , Abhinav Valada

Diffusion probabilistic models have recently achieved remarkable success in generating high-quality images. However, balancing high perceptual quality and low distortion remains challenging in application of diffusion models in image…

Image and Video Processing · Electrical Eng. & Systems 2025-12-23 Juan Song , Jiaxiang He , Lijie Yang , Mingtao Feng , Keyan Wang

Biopharmaceutical products, particularly monoclonal antibodies (mAbs), have gained prominence in the pharmaceutical market due to their high specificity and efficacy. As these products are projected to constitute a substantial portion of…

Quantitative Methods · Quantitative Biology 2024-09-05 Thanh Tung Khuat , Robert Bassett , Ellen Otte , Bogdan Gabrys

Point-wise localization of individual fluorophores is a critical step in super-resolution microscopy and single particle tracking. Although the methods are limited by the accuracy in localizing individual flourophores, this point-wise…

Biological Physics · Physics 2017-05-08 Martin Lindén , Vladimir Ćurić , Elias Amselem , Johan Elf

Uncertainty quantification (UQ) is an important component of molecular property prediction, particularly for drug discovery applications where model predictions direct experimental design and where unanticipated imprecision wastes valuable…

Machine Learning · Computer Science 2020-05-21 Lior Hirschfeld , Kyle Swanson , Kevin Yang , Regina Barzilay , Connor W. Coley

Molecular dynamics simulation is now a widespread approach for understanding complex systems on the atomistic scale. It finds applications from physics and chemistry to engineering, life and medical science. In the last decade, the approach…

Computational Physics · Physics 2021-04-28 Shunzhou Wan , Robert C. Sinclair , Peter V. Coveney

Scientific applications typically generate large volumes of floating-point data, making lossy compression one of the most effective methods for data reduction, thereby lowering storage requirements and improving performance in large-scale…

Performance · Computer Science 2024-12-11 Youyuan Liu , Taolue Yang , Sian Jin

The miscibility in several polymer blend mixtures (polymethylmethacrylate/polystyrene, (1,4-cis) polyisoprene/polystyrene, and polymethylmethacrylate/polyoxyethylene) has been investigated using Molecular Dynamics simulations for atomistic…

Chemical Physics · Physics 2009-05-29 Amirhossein Ahmadi , Juan J. Freire

This paper presents a probabilistic approach to represent and quantify model-form uncertainties in the reduced-order modeling of complex systems using operator inference techniques. Such uncertainties can arise in the selection of an…

Machine Learning · Statistics 2024-11-08 Jin Yi Yong , Rudy Geelen , Johann Guilleminot

ML models have errors when used for predictions. The errors are unknown but can be quantified by model uncertainty. When multiple ML models are trained using the same training points, their model uncertainties may be statistically…

Machine Learning · Statistics 2025-09-23 Xiaoping Du

Modern autonomous systems with machine learning components often use uncertainty quantification to help produce assurances about system operation. However, there is a lack of consensus in the community on what uncertainty is and how to…

Systems and Control · Electrical Eng. & Systems 2026-01-27 Sampada Deglurkar , Haotian Shen , Anish Muthali , Marco Pavone , Dragos Margineantu , Peter Karkus , Boris Ivanovic , Claire J. Tomlin

We determine the uncertainties on observables arising from the errors on the experimental data that are fitted in the global MRST2001 parton analysis. By diagonalizing the error matrix we produce sets of partons suitable for use within the…

High Energy Physics - Phenomenology · Physics 2011-09-13 A. D. Martin , R. G. Roberts , W. J. Stirling , R. S. Thorne

Entangled polymers are deformed by a strong shear flow. The shape of the polymer, called the form factor, is measured by small angle neutron scattering. However, the real-space molecular structure is not directly available from the…

For objects in the low Earth orbit region, uncertainty in atmospheric density estimation is an important source of orbit prediction error, which is critical for space situational awareness activities such as the satellite conjunction…

Space Physics · Physics 2022-11-01 Smriti Nandan Paul , Richard J. Licata , Piyush M. Mehta

The quantum rotor represents, after the harmonic oscillator, the next obvious quantum system to study the complementary pair of variables: the angular momentum and the unitary shift operator in angular momentum. Proper quantification of…

Quantum Physics · Physics 2024-08-13 Ladislav Mišta , Matouš Mišta , Zdeněk Hradil

Quantifying a model's predictive uncertainty is essential for safety-critical applications such as autonomous driving. We consider quantifying such uncertainty for multi-object detection. In particular, we leverage conformal prediction to…

Computer Vision and Pattern Recognition · Computer Science 2024-07-31 Alexander Timans , Christoph-Nikolas Straehle , Kaspar Sakmann , Eric Nalisnick

An important paradigm in 3D object detection is the use of multiple modalities to enhance accuracy in both normal and challenging conditions, particularly for long-tail scenarios. To address this, recent studies have explored two directions…

Computer Vision and Pattern Recognition · Computer Science 2024-10-17 Minkyoung Cho , Yulong Cao , Jiachen Sun , Qingzhao Zhang , Marco Pavone , Jeong Joon Park , Heng Yang , Z. Morley Mao