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The estimation of uncertainties associated with predictions from quantitative structure-activity relationship (QSAR) models can accelerate the drug discovery process by identifying promising experiments and allowing an efficient allocation…

Machine Learning · Computer Science 2025-02-07 Hannah Rosa Friesacher , Emma Svensson , Susanne Winiwarter , Lewis Mervin , Adam Arany , Ola Engkvist

This study proposes a linear approach for propagating uncertainties in the multiline thru-reflect-line (TRL) calibration method for vector network analyzers. The multiline TRL formulation we are proposing applies the law of uncertainty…

Signal Processing · Electrical Eng. & Systems 2023-07-19 Ziad Hatab , Michael Ernst Gadringer , Wolfgang Bösch

We propose an approximate Bayesian method for quantifying the total uncertainty in inverse PDE solutions obtained with machine learning surrogate models, including operator learning models. The proposed method accounts for uncertainty in…

Machine Learning · Computer Science 2024-08-22 Yuanzhe Wang , Alexandre M. Tartakovsky

This paper presents a computational framework for the robust stiffness design of hyperelastic structures at finite deformations subject to various uncertain sources. In particular, the loading, material properties, and geometry…

Computational Engineering, Finance, and Science · Computer Science 2025-01-28 Nan Feng , Guodong Zhang , Kapil Khandelwal

Bayesian inference is a popular approach to calibrating uncertainties, but it can underpredict such uncertainties when model misspecification is present, impacting its reliability to inform decision making. Recently, the statistics and…

Computational Engineering, Finance, and Science · Computer Science 2026-01-09 Rebekah White , Rileigh Bandy , Teresa Portone

We derive the general analytical expressions for the statistical uncertainties of cumulants up to fourth order including an efficiency correction. The analytical expressions have been tested with a toy Monte Carlo model analysis. An…

Nuclear Theory · Physics 2022-03-25 Fan Si , Yifei Zhang

Linear covariance (LinCov) techniques have gained widespread traction in the modeling of uncertainty, including in the preliminary study of spacecraft navigation performance. While LinCov methods offer improved computational efficiency…

Signal Processing · Electrical Eng. & Systems 2025-12-30 Jackson Kulik , Braden Hastings , Keith A. LeGrand

In the present paper, several types of efficiency conditions are established for vector optimization problems with cone constraints affected by uncertainty, but with no information of stochastic nature about the uncertain data. Following a…

Optimization and Control · Mathematics 2021-02-01 Amos Uderzo

This paper addresses the problem of quantification and propagation of uncertainties associated with dependence modeling when data for characterizing probability models are limited. Practically, the system inputs are often assumed to be…

Computation · Statistics 2020-04-14 Jiaxin Zhang , Michael D. Shields

We consider the dictionary-based ROM-net (Reduced Order Model) framework [T. Daniel, F. Casenave, N. Akkari, D. Ryckelynck, Model order reduction assisted by deep neural networks (ROM-net), Advanced modeling and Simulation in Engineering…

Machine Learning · Statistics 2023-02-02 Thomas Daniel , Fabien Casenave , Nissrine Akkari , David Ryckelynck , Christian Rey

This work suggests several methods of uncertainty treatment in multiscale modelling and describes their application to a system of coupled turbulent transport simulations of a tokamak plasma. We propose a method to quantify the usually…

Plasma Physics · Physics 2023-07-10 Yehor Yudin , David Coster , Udo von Toussaint , Frank Jenko

In robust optimization one seeks to make a decision under uncertainty, where the goal is to find the solution with the best worst-case performance. The set of possible realizations of the uncertain data is described by a so-called…

Optimization and Control · Mathematics 2022-01-25 Immanuel Bomze , Markus Gabl

Data-driven turbulence modelling approaches are gaining increasing interest from the CFD community. However, the introduction of a machine learning (ML) model introduces a new source of uncertainty, the ML model itself. Quantification of…

Fluid Dynamics · Physics 2021-01-12 Ashley Scillitoe , Pranay Seshadri , Mark Girolami

As the sensitivity and uncertainty analysis of nuclear system can provide more confident bounds for the Best-estimate Prediction used to assess the performance and safety of nuclear plant, the uncertainty and sensitivity analysis has been a…

Applied Physics · Physics 2017-04-24 JiaYi Xu , Xu Bo Ma , Fan Lu , Yi Xue Chen

When systems use data-based models that are based on machine learning (ML), errors in their results cannot be ruled out. This is particularly critical if it remains unclear to the user how these models arrived at their decisions and if…

Machine Learning · Computer Science 2023-11-10 Lisa Jöckel , Michael Kläs , Georg Popp , Nadja Hilger , Stephan Fricke

Load forecasting has long been recognized as an important building block for all utility operational planning efforts. Over the recent years, it has become ever more challenging to make accurate forecasts due to the proliferation of…

Systems and Control · Computer Science 2019-05-17 Guangrui Xie , Xi Chen , Yang Weng

In a data-scarce field such as healthcare, where models often deliver predictions on patients with rare conditions, the ability to measure the uncertainty of a model's prediction could potentially lead to improved effectiveness of decision…

Machine Learning · Statistics 2020-05-26 Lotta Meijerink , Giovanni Cinà , Michele Tonutti

Owing to the production process, short fiber reinforced composites exhibit a pronounced anisotropy of both elastic properties and crack growth resistance. In particular the latter issue has a major impact on crack deflection and inevitably…

Materials Science · Physics 2022-05-04 Andreas Ricoeur , Felix Lindner , Konstantin Zarjov

Quantifying and reducing uncertainty in Earth system model parameterizations is essential to improving their reliability in decision-making. Forward uncertainty propagation is used to derive parameter sensitivity but requires physically…

Atmospheric and Oceanic Physics · Physics 2026-04-22 Ethan YoungIn Shin , Baris Kale , Michael F. Howland

Geothermal field modeling is often associated with uncertainties related to the subsurface static properties and the dynamics of fluid flow and heat transfer. Uncertainty quantification using simulations is a useful tool to design optimum…

Geophysics · Physics 2021-12-13 Hussein Hoteit , Xupeng He , Bicheng Yan , Volker Vahrenkam