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Accurate extraction of Alzheimer's Disease and Related Dementias (ADRD) phenotypes from electronic health records (EHR) is critical for early-stage detection and disease staging. However, this information is usually embedded in unstructured…

Artificial Intelligence · Computer Science 2026-03-17 Mingchen Shao , Yuzhang Xie , Carl Yang , Jiaying Lu

Alzheimers disease (AD) is a severe neurological brain disorder. It is not curable, but earlier detection can help improve symptoms in a great deal. The machine learning based approaches are popular and well motivated models for medical…

Image and Video Processing · Electrical Eng. & Systems 2024-05-17 Lilia Lazli

Alzheimer's disease (AD) is a progressive neurodegenerative disorder that leads to irreversible cognitive decline in memory and communication. Early detection of AD through speech analysis is crucial for delaying disease progression.…

Sound · Computer Science 2026-02-09 Yifan Gao , Long Guo , Hong Liu

Speech-based automatic detection of Alzheimer's disease (AD) and depression has attracted increased attention. Confidence estimation is crucial for a trust-worthy automatic diagnostic system which informs the clinician about the confidence…

Computation and Language · Computer Science 2024-09-10 Wen Wu , Chao Zhang , Philip C. Woodland

Alzheimer's disease (AD) constitutes a neurodegenerative disease with serious consequences to peoples' everyday lives, if it is not diagnosed early since there is no available cure. Alzheimer's is the most common cause of dementia, which…

Computation and Language · Computer Science 2023-01-18 Loukas Ilias , Dimitris Askounis , John Psarras

As large language models (LLMs) grow in parameter size and capabilities, such as interaction through prompting, they open up new ways of interfacing with automatic speech recognition (ASR) systems beyond rescoring n-best lists. This work…

Audio and Speech Processing · Electrical Eng. & Systems 2024-09-25 Maryam Naderi , Enno Hermann , Alexandre Nanchen , Sevada Hovsepyan , Mathew Magimai. -Doss

Objective: Clinical documentation contains factual, diagnostic, and management errors that can compromise patient safety. Large language models (LLMs) may help detect and correct such errors, but their behavior under different prompting…

Computation and Language · Computer Science 2025-11-27 Farzad Ahmed , Joniel Augustine Jerome , Meliha Yetisgen , Özlem Uzuner

Alzheimers Disease (AD) is a progressive neurodegenerative disorder that poses significant challenges in its early diagnosis, often leading to delayed treatment and poorer outcomes for patients. Traditional diagnostic methods, typically…

Machine Learning · Computer Science 2025-08-06 Tatwadarshi P Nagarhalli , Sanket Patil , Vishal Pande , Uday Aswalekar , Prafulla Patil

Automatic speech recognition (ASR) models rely on high-quality transcribed data for effective training. Generating pseudo-labels for large unlabeled audio datasets often relies on complex pipelines that combine multiple ASR outputs through…

Audio and Speech Processing · Electrical Eng. & Systems 2025-10-06 Jeena Prakash , Blessingh Kumar , Kadri Hacioglu , Bidisha Sharma , Sindhuja Gopalan , Malolan Chetlur , Shankar Venkatesan , Andreas Stolcke

Neurological disorders that affect speech production, such as Alzheimer's Disease (AD), significantly impact the lives of both patients and caregivers, whether through social, psycho-emotional effects or other aspects not yet fully…

We propose to utilize an instruction-tuned large language model (LLM) for guiding the text generation process in automatic speech recognition (ASR). Modern large language models (LLMs) are adept at performing various text generation tasks…

Audio and Speech Processing · Electrical Eng. & Systems 2025-01-08 Yosuke Higuchi , Tetsuji Ogawa , Tetsunori Kobayashi

Large Language Models (LLMs) are machine learning models that have seen widespread adoption due to their capability of handling previously difficult tasks. LLMs, due to their training, are sensitive to how exactly a question is presented,…

Software Engineering · Computer Science 2025-12-22 Jae Yong Lee , Sungmin Kang , Shin Yoo

Connecting audio encoders with large language models (LLMs) allows the LLM to perform various audio understanding tasks, such as automatic speech recognition (ASR) and audio captioning (AC). Most research focuses on training an adapter…

Audio and Speech Processing · Electrical Eng. & Systems 2025-09-22 Weiqiao Shan , Yuang Li , Yuhao Zhang , Yingfeng Luo , Chen Xu , Xiaofeng Zhao , Long Meng , Yunfei Lu , Min Zhang , Hao Yang , Tong Xiao , Jingbo Zhu

Language modeling (LM) for automatic speech recognition (ASR) does not usually incorporate utterance level contextual information. For some domains like voice assistants, however, additional context, such as the time at which an utterance…

Computation and Language · Computer Science 2021-06-04 Richard Diehl Martinez , Scott Novotney , Ivan Bulyko , Ariya Rastrow , Andreas Stolcke , Ankur Gandhe

Alzheimers Disease AD is an acute neuro disease that degenerates the brain cells and thus leads to memory loss progressively. It is a fatal brain disease that mostly affects the elderly. It steers the decline of cognitive and biological…

Machine Learning · Computer Science 2023-04-20 Nair Bini Balakrishnan , P. S. Sreeja , Jisha Jose Panackal

Alzheimer's Disease (AD) is a progressive neurodegenerative condition that adversely affects cognitive abilities. Language-related changes can be automatically identified through the analysis of outputs from linguistic assessment tasks,…

Alzheimer's Disease Analysis Model (ADAM) is a multi-agent reasoning large language model (LLM) framework designed to integrate and analyze multimodal data, including microbiome profiles, clinical datasets, and external knowledge bases, to…

Artificial Intelligence · Computer Science 2025-08-22 Ziyuan Huang , Vishaldeep Kaur Sekhon , Roozbeh Sadeghian , Maria L. Vaida , Cynthia Jo , Doyle Ward , Vanni Bucci , John P. Haran

Early and accurate diagnosis of Alzheimer's disease (AD) and its prodromal period mild cognitive impairment (MCI) is essential for the delayed disease progression and the improved quality of patients'life. The emerging computer-aided…

Image and Video Processing · Electrical Eng. & Systems 2021-07-29 Fan Zhang , Bo Pan , Pengfei Shao , Peng Liu , Shuwei Shen , Peng Yao , Ronald X. Xu

Anomaly detection (AD) is an important machine learning task with many real-world uses, including fraud detection, medical diagnosis, and industrial monitoring. Within natural language processing (NLP), AD helps detect issues like spam,…

Computation and Language · Computer Science 2025-10-13 Tiankai Yang , Yi Nian , Shawn Li , Ruiyao Xu , Yuangang Li , Jiaqi Li , Zhuo Xiao , Xiyang Hu , Ryan Rossi , Kaize Ding , Xia Hu , Yue Zhao

Alzheimer's disease is a progressive, neurodegenerative disorder that causes memory loss and cognitive decline. While there has been extensive research in applying deep learning models to Alzheimer's prediction tasks, these models remain…

Computer Vision and Pattern Recognition · Computer Science 2025-09-15 Emily Kaczmarek , Justin Szeto , Brennan Nichyporuk , Tal Arbel
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