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Treatment planning in radiotherapy is inherently a multi-criteria optimization (MCO) problem. Traditionally, the treatment's robustness is not formulated as a part of this decision making problem, but dealt with separately through margins…

Medical Physics · Physics 2026-03-27 Remo Cristoforetti , Philipp Süss , Tobias Becher , Niklas Wahl

Subset selection with cost constraints aims to select a subset from a ground set to maximize a monotone objective function without exceeding a given budget, which has various applications such as influence maximization and maximum coverage.…

Data Structures and Algorithms · Computer Science 2024-09-10 Dan-Xuan Liu , Chao Qian

State-of-the-art multi-objective optimization often assumes a known utility function, learns it interactively, or computes the full Pareto front-each requiring costly expert input.~Real-world problems, however, involve implicit preferences…

Machine Learning · Computer Science 2025-10-01 Farha A. Khan , Tanmay Chakraborty , Jörg P. Dietrich , Christian Wirth

A multiple objective simulation optimization algorithm named Multiple Objective Probabilistic Branch and Bound with Single Observation (MOPBnB(so)) is presented for approximating the Pareto optimal set and the associated efficient frontier…

Optimization and Control · Mathematics 2025-06-06 Hao Huang , Zelda B. Zabinsky

Recent deep reinforcement learning methods have achieved remarkable success in solving multi-objective combinatorial optimization problems (MOCOPs) by decomposing them into multiple subproblems, each associated with a specific weight…

Artificial Intelligence · Computer Science 2026-03-23 Mingfeng Fan , Jianan Zhou , Yifeng Zhang , Yaoxin Wu , Jinbiao Chen , Guillaume Adrien Sartoretti

Robotic systems often require a team of robots to collectively visit multiple targets while optimizing competing objectives, such as total travel cost and makespan. This setting can be formulated as the Multi-Objective Multiple Traveling…

Robotics · Computer Science 2026-03-20 Fengxiaoxiao Li , Xiao Mao , Mingfeng Fan , Yifeng Zhang , Yi Li , Tanishq Duhan , Guillaume Sartoretti

We consider the problem of constrained multi-objective blackbox optimization using expensive function evaluations, where the goal is to approximate the true Pareto set of solutions satisfying a set of constraints while minimizing the number…

Machine Learning · Computer Science 2020-11-24 Syrine Belakaria , Aryan Deshwal , Janardhan Rao Doppa

Fine-tuning large language models (LLMs) on human preferences, typically through reinforcement learning from human feedback (RLHF), has proven successful in enhancing their capabilities. However, ensuring the safety of LLMs during…

Artificial Intelligence · Computer Science 2025-04-09 Wenxuan Zhang , Philip H. S. Torr , Mohamed Elhoseiny , Adel Bibi

Creating meaningful interpretations for black-box machine learning models involves balancing two often conflicting objectives: accuracy and explainability. Exploring the trade-off between these objectives is essential for developing…

Machine Learning · Computer Science 2025-08-22 Aniruddha Joshi , Supratik Chakraborty , S Akshay , Shetal Shah , Hazem Torfah , Sanjit Seshia

MINLO (mixed-integer nonlinear optimization) formulations of the disjunction between the origin and a polytope via a binary indicator variable have broad applicability in nonlinear combinatorial optimization, for modeling a fixed cost $c$…

Optimization and Control · Mathematics 2023-02-07 Luze Xu , Jon Lee

Multi-modal models excel in cross-modal tasks but are computationally expensive due to their billions of parameters. Parameter-efficient fine-tuning (PEFT) offers a solution by adding small trainable components while freezing pre-trained…

Machine Learning · Computer Science 2025-03-27 Sashuai Zhou , Hai Huang , Yan Xia

In this work we are interested in stochastic particle methods for multi-objective optimization. The problem is formulated using parametrized, single-objective sub-problems which are solved simultaneously. To this end a consensus based…

Optimization and Control · Mathematics 2022-08-03 Giacomo Borghi , Michael Herty , Lorenzo Pareschi

Mental health disorders affect over 1 billion people worldwide, yet access to care remains limited by workforce shortages and cost constraints. While AI systems show therapeutic promise, current alignment approaches optimize objectives…

Recent methods leverage a hypernet to handle the performance-fairness trade-offs in federated learning. This hypernet maps the clients' preferences between model performance and fairness to preference-specifc models on the trade-off curve,…

Machine Learning · Computer Science 2025-05-01 Rongguang Ye , Ming Tang

Automated experimentation has the potential to revolutionize scientific discovery, but its effectiveness depends on well-defined optimization targets, which are often uncertain or probabilistic in real-world settings. In this work, we…

Machine Learning · Computer Science 2025-04-10 Yu Liu , Sergei V. Kalinin

Preference optimization methods such as DPO align large language models (LLMs) using paired comparisons, but their effectiveness can be highly sensitive to the quality and difficulty of preference pairs. A common heuristic treats…

Artificial Intelligence · Computer Science 2026-02-03 Jinlong Pang , Zhaowei Zhu , Na Di , Yichi Zhang , Yaxuan Wang , Chen Qian , Yang Liu

Choosing a suitable ML model is a complex task that can depend on several objectives, e.g., accuracy, fairness, or energy consumption. In practice, this requires trading off multiple, often competing, objectives through multi-objective…

Machine Learning · Computer Science 2026-05-07 Daphne Theodorakopoulos , Marcel Wever , Marius Lindauer

Federated learning (FL) is a widely adopted paradigm for privacy-preserving model training, but FedAvg optimise for the majority while under-serving minority clients. Existing methods such as federated multi-objective learning (FMOL)…

Machine Learning · Computer Science 2025-08-26 Jiansheng Rao , Jiayi Li , Zhizhi Gong , Soummya Kar , Haoxuan Li

We propose Soft Preference Optimization (SPO), a method for aligning generative models, such as Large Language Models (LLMs), with human preferences, without the need for a reward model. SPO optimizes model outputs directly over a…

Machine Learning · Computer Science 2024-10-07 Arsalan Sharifnassab , Saber Salehkaleybar , Sina Ghiassian , Surya Kanoria , Dale Schuurmans

The alignment of large language models (LLMs) with human preferences remains a key challenge. While post-training techniques like Reinforcement Learning from Human Feedback (RLHF) and Direct Preference Optimization (DPO) have achieved…

Artificial Intelligence · Computer Science 2025-07-11 Qingyu Yin , Chak Tou Leong , Minjun Zhu , Hanqi Yan , Qiang Zhang , Yulan He , Wenjie Li , Jun Wang , Yue Zhang , Linyi Yang