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Related papers: Studying the Cycle Complexity of DNA Synthesis

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Printing custom DNA sequences is essential to scientific and biomedical research, but the technology can be used to manufacture plagues as well as cures. Just as ink printers recognize and reject attempts to counterfeit money, DNA…

The exponentially increasing demand for data storage has been facing more and more challenges during the past years. The energy costs that it represents are also increasing, and the availability of the storage hardware is not able to follow…

Image and Video Processing · Electrical Eng. & Systems 2022-03-21 Xavier Pic , Marc Antonini

Artificial synthesis of DNA molecules is an essential part of the study of biological mechanisms. The design of a synthetic DNA molecule usually involves many objectives. One of the important objectives is to eliminate short sequence…

Biomolecules · Quantitative Biology 2021-08-13 Zehavit Leibovich , Ilan Gronau

The biochemical processes underlying DNA data storage, including synthesis, amplification, and sequencing, are inherently noisy. Consequently, base-level insertion, deletion, and substitution (IDS) errors, as well as sequence-level…

Information Theory · Computer Science 2026-03-17 Ramy Khabbaz , Jérémy Mateos , Marc Antonini , Serge Kas Hanna

As a possible implementation of data storage using DNA, multiple strands of DNA are stored in a liquid container so that, in the future, they can be read by an array of DNA readers in parallel. These readers will sample the strands with…

Information Theory · Computer Science 2024-09-04 Hsin-Po Wang , Venkatesan Guruswami

DNA Data storage has recently attracted much attention due to its durable preservation and extremely high information density (bits per gram) properties. In this work, we propose a hybrid coding strategy comprising of generalized…

Information Theory · Computer Science 2021-12-20 Yixin Wang , Li Deng , Md. Noor-A-Rahim , Erry Gunawan , Yong L. Guan , Zhi P. Shi , Chueh L. Poh

In this paper, we study error-correcting codes for the storage of data in synthetic deoxyribonucleic acid (DNA). We investigate a storage model where data is represented by an unordered set of $M$ sequences, each of length $L$. Errors…

Information Theory · Computer Science 2018-05-10 Andreas Lenz , Paul H. Siegel , Antonia Wachter-Zeh , Eitan Yaakobi

Computational cost of training state-of-the-art deep models in many learning problems is rapidly increasing due to more sophisticated models and larger datasets. A recent promising direction for reducing training cost is dataset…

Machine Learning · Computer Science 2022-12-23 Bo Zhao , Hakan Bilen

Formal methods apply algorithms based on mathematical principles to enhance the reliability of systems. It would only be natural to try to progress from verification, model checking or testing a system against its formal specification into…

Software Engineering · Computer Science 2014-02-28 Gal Katz , Doron Peled

Motivated by DNA based data storage system, we investigate the errors that occur when synthesizing DNA strands in parallel, where each strand is appended one nucleotide at a time by the machine according to a template supersequence. If…

Information Theory · Computer Science 2024-05-06 Ziyang Lu , Han Mao Kiah , Yiwei Zhang , Robert N. Grass , Eitan Yaakobi

DNA exhibits remarkable potential as a data storage solution due to its impressive storage density and long-term stability, stemming from its inherent biomolecular structure. However, developing this novel medium comes with its own set of…

Image and Video Processing · Electrical Eng. & Systems 2023-09-14 Trung Hieu Le , Xavier Pic , Jeremy Mateos , Marc Antonini

Researchers in the field of DNA-based chaotic cryptography have recently proposed a set of novel and efficient image encryption algorithms. In this paper, we present a comprehensive summary of those techniques, which are available in the…

Cryptography and Security · Computer Science 2015-05-08 Chiranjoy Chattopadhyay , Bikramjit Sarkar , Debaprasad Mukherjee

The great success of machine learning with massive amounts of data comes at a price of huge computation costs and storage for training and tuning. Recent studies on dataset condensation attempt to reduce the dependence on such massive data…

Machine Learning · Computer Science 2022-06-03 Jang-Hyun Kim , Jinuk Kim , Seong Joon Oh , Sangdoo Yun , Hwanjun Song , Joonhyun Jeong , Jung-Woo Ha , Hyun Oh Song

Data storage is one of the main computing issues of this century. Not only storage devices are converging to strict physical limits, but also the amount of data generated by users is growing at an unbelievable rate. To face these…

Cryptography and Security · Computer Science 2020-09-29 Federico Tavella , Alberto Giaretta , Mauro Conti , Sasitharan Balasubramaniam

We present a finite blocklength performance bound for a DNA storage channel with insertions, deletions, and substitutions. The considered bound -- the dependency testing (DT) bound, introduced by Polyanskiy et al. in 2010 -- provides an…

Information Theory · Computer Science 2023-08-07 Issam Maarouf , Gianluigi Liva , Eirik Rosnes , Alexandre Graell i Amat

DNA is emerging as an increasingly attractive medium for data storage due to a number of important and unique advantages it offers, most notably the unprecedented durability and density. While the technology is evolving rapidly, the…

Emerging Technologies · Computer Science 2022-05-03 Dehui Lin , Yasamin Tabatabaee , Yash Pote , Djordje Jevdjic

Storing digital data in synthetic DNA faces challenges in ensuring data reliability in the presence of edit errors--deletions, insertions, and substitutions--that occur randomly during various stages of the storage process. Current…

Information Theory · Computer Science 2025-09-11 Serge Kas Hanna

DNA as a data storage medium has several advantages, including far greater data density compared to electronic media. We propose that schemes for data storage in the DNA of living organisms may benefit from studying the reconstruction…

Information Theory · Computer Science 2019-09-10 Yonatan Yehezkeally , Moshe Schwartz

Due to the redundant nature of DNA synthesis and sequencing technologies, a basic model for a DNA storage system is a multi-draw "shuffling-sampling" channel. In this model, a random number of noisy copies of each sequence is observed at…

Information Theory · Computer Science 2021-12-06 Kel Levick , Reinhard Heckel , Ilan Shomorony

To increase the information capacity of DNA storage, composite DNA letters were introduced. We propose a novel channel model for composite DNA in which composite sequences are decomposed into ordered standard non-composite sequences. The…

Information Theory · Computer Science 2025-10-31 Besart Dollma , Ohad Elishco , Eitan Yaakobi