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Clinical Question Answering (QA) systems enable doctors to quickly access patient information from electronic health records (EHRs). However, training these systems requires significant annotated data, which is limited due to the expertise…

Computation and Language · Computer Science 2024-12-09 Fan Bai , Keith Harrigian , Joel Stremmel , Hamid Hassanzadeh , Ardavan Saeedi , Mark Dredze

This survey reviews how large language models (LLMs) are transforming synthetic training data generation in both natural language and code domains. By producing artificial but task-relevant examples, these models can significantly augment…

Computation and Language · Computer Science 2025-11-21 Mihai Nadas , Laura Diosan , Andreea Tomescu

Data quality remains an important challenge in data-driven systems, as errors in tabular data can severely compromise downstream analytics and machine learning performance. Although numerous error detection algorithms have been proposed,…

Databases · Computer Science 2026-03-10 Xinyuan Liu , Jiahui Chen , Bocheng Hu , Yu Sun , Xinyang Chen , Shaoxu Song , Yongxin Tong

Generation of realistic synthetic data has garnered considerable attention in recent years, particularly in the health research domain due to its utility in, for instance, sharing data while protecting patient privacy or determining optimal…

Other Statistics · Statistics 2025-01-30 Niki Z. Petrakos , Erica E. M. Moodie , Nicolas Savy

Generating clinical synthetic text represents an effective solution for common clinical NLP issues like sparsity and privacy. This paper aims to conduct a systematic review on generating synthetic medical free-text by formulating…

Computation and Language · Computer Science 2025-07-25 Basel Alshaikhdeeb , Ahmed Abdelmonem Hemedan , Soumyabrata Ghosh , Irina Balaur , Venkata Satagopam

The increasing use of synthetic data generated by Large Language Models (LLMs) presents both opportunities and challenges in data-driven applications. While synthetic data provides a cost-effective, scalable alternative to real-world data…

Computation and Language · Computer Science 2025-07-25 Tevin Atwal , Chan Nam Tieu , Yefeng Yuan , Zhan Shi , Yuhong Liu , Liang Cheng

Synthetic Data Generation (SDG), leveraging Large Language Models (LLMs), has recently been recognized and broadly adopted as an effective approach to improve the performance of smaller but more resource and compute efficient LLMs through…

Machine Learning · Computer Science 2026-03-25 Srideepika Jayaraman , Achille Fokoue , Dhaval Patel , Jayant Kalagnanam

The success of Large Language Models (LLMs) is inherently linked to the availability of vast, diverse, and high-quality data for training and evaluation. However, the growth rate of high-quality data is significantly outpaced by the…

Computation and Language · Computer Science 2024-10-18 Ke Wang , Jiahui Zhu , Minjie Ren , Zeming Liu , Shiwei Li , Zongye Zhang , Chenkai Zhang , Xiaoyu Wu , Qiqi Zhan , Qingjie Liu , Yunhong Wang

Generating datasets that "look like" given real ones is an interesting tasks for healthcare applications of ML and many other fields of science and engineering. In this paper we propose a new method of general application to binary datasets…

Machine Learning · Statistics 2018-07-05 Laura Aviñó , Matteo Ruffini , Ricard Gavaldà

Machine learning (ML) and Natural Language Processing (NLP) have achieved remarkable success in many fields and have brought new opportunities and high expectation in the analyses of medical data. The most common type of medical data is the…

Computation and Language · Computer Science 2018-12-10 Jiaqi Guan , Runzhe Li , Sheng Yu , Xuegong Zhang

The application of machine learning on tabular data in specialized domains is severely limited by data scarcity. While generative models offer a solution, traditional methods falter in low-data regimes, and recent Large Language Models…

Machine Learning · Computer Science 2025-08-05 Siyi Liu , Yujia Zheng , Yongqi Zhang

Accurate and comprehensive clinical documentation is crucial for delivering high-quality healthcare, facilitating effective communication among providers, and ensuring compliance with regulatory requirements. However, manual transcription…

Computation and Language · Computer Science 2024-06-12 Anjanava Biswas , Wrick Talukdar

The scarcity of high-quality annotated medical data, particularly in mental health, poses a significant bottleneck for training robust machine learning models. Privacy regulations restrict data sharing, making synthetic data generation a…

Synthetic data generation has recently gained widespread attention as a more reliable alternative to traditional data anonymization. The involved methods are originally developed for image synthesis. Hence, their application to the…

Sensitive medical data is often subject to strict usage constraints. In this paper, we trained a generative adversarial network (GAN) on real-world electronic health records (EHR). It was then used to create a data-set of "fake" patients…

Machine Learning · Computer Science 2021-09-07 John Weldon , Tomas Ward , Eoin Brophy

Tabular data synthesis involves not only multi-table synthesis but also generating multi-modal data (e.g., strings and categories), which enables diverse knowledge synthesis. However, separating numerical and categorical data has limited…

Machine Learning · Computer Science 2025-03-21 Tung Sum Thomas Kwok , Chi-Hua Wang , Guang Cheng

The challenge of accessing historical patient data for clinical research, while adhering to privacy regulations, is a significant obstacle in medical science. An innovative approach to circumvent this issue involves utilising synthetic…

Computation and Language · Computer Science 2024-03-15 Erlend Frayling , Jake Lever , Graham McDonald

Machine learning (ML) holds great promise for clinical applications but is often hindered by limited access to high-quality data due to privacy concerns, high costs, and long timelines associated with clinical trials. While large language…

Computation and Language · Computer Science 2026-03-27 Zerui Xu , Fang Wu , Yingzhou Lu , Yuanyuan Zhang , Yue Zhao

The recent surge in research focused on generating synthetic data from large language models (LLMs), especially for scenarios with limited data availability, marks a notable shift in Generative Artificial Intelligence (AI). Their ability to…

Machine Learning · Computer Science 2024-03-08 Xu Guo , Yiqiang Chen

Generating high-fidelity synthetic tabular data remains a critical challenge for enhancing data availability in privacy-sensitive and low-resource domains. Recent approaches leverage LLMs by representing table rows as sequences, yet suffer…

Machine Learning · Computer Science 2026-04-28 Shuo Yang , Zheyu Zhang , Bardh Prenkaj , Gjergji Kasneci