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The BrainScaleS-2 (BSS-2) system implements physical models of neurons as well as synapses and aims for an energy-efficient and fast emulation of biological neurons. When replicating neuroscientific experiments on BSS-2, a major challenge…

Neural and Evolutionary Computing · Computer Science 2023-11-21 Jakob Kaiser , Raphael Stock , Eric Müller , Johannes Schemmel , Sebastian Schmitt

Our work utilized a non-sequential simulation-based inference algorithm to provide an amortized neural density estimator, which approximates the posterior distribution for seven parameters of the adaptive exponential integrate-and-fire…

Neural and Evolutionary Computing · Computer Science 2026-02-13 Jakob Kaiser , Eric Müller , Johannes Schemmel

Neural Posterior Estimation (NPE) enables rapid parameter inference for complex simulators with intractable likelihoods. NPE trains an inference network to estimate a probability density over parameters given data, typically assumed to be…

Machine Learning · Computer Science 2026-05-14 Jan Boelts , Cornelius Schröder , Jonas Beck , Jakob H. Macke , Michael Deistler , Daniel Gedon

Mechanistic models of single-neuron dynamics have been extensively studied in computational neuroscience. However, identifying which models can quantitatively reproduce empirically measured data has been challenging. We propose to overcome…

Analog neuromorphic hardware promises fast brain emulation on the one hand and an efficient implementation of novel, brain-inspired computing paradigms on the other. Bridging this spectrum requires flexibly configurable circuits with…

Neural and Evolutionary Computing · Computer Science 2022-09-21 Sebastian Billaudelle , Johannes Weis , Philipp Dauer , Johannes Schemmel

Sequential neural posterior estimation (SNPE) techniques have been recently proposed for dealing with simulation-based models with intractable likelihoods. Unlike approximate Bayesian computation, SNPE techniques learn the posterior from…

Machine Learning · Statistics 2025-01-17 Yifei Xiong , Xiliang Yang , Sanguo Zhang , Zhijian He

Stack autoencoder (SAE), as a representative deep network, has unique and excellent performance in feature learning, and has received extensive attention from researchers. However, existing deep SAEs focus on original samples without…

Machine Learning · Computer Science 2022-10-28 Chuanyan Zhou , Jie Ma , Fan Li , Yongming Li , Pin Wang , Xiaoheng Zhang

Computer simulations have long presented the exciting possibility of scientific insight into complex real-world processes. Despite the power of modern computing, however, it remains challenging to systematically perform inference under…

Machine Learning · Computer Science 2024-12-10 Sam Griesemer , Defu Cao , Zijun Cui , Carolina Osorio , Yan Liu

Simulation-based inference (SBI) with neural posterior estimation (NPE) provides rapid X-ray spectral fitting in both Gaussian and Poisson regimes by learning approximate parameter posteriors from simulations. We investigate auto-encoders…

Instrumentation and Methods for Astrophysics · Physics 2026-04-22 Didier Barret , Simon Dupourqué

There has been a lot of recent interest in designing neural network models to estimate a distribution from a set of examples. We introduce a simple modification for autoencoder neural networks that yields powerful generative models. Our…

Machine Learning · Computer Science 2015-06-08 Mathieu Germain , Karol Gregor , Iain Murray , Hugo Larochelle

Modern simulation-based inference techniques use neural networks to solve inverse problems efficiently. One notable strategy is neural posterior estimation (NPE), wherein a neural network parameterizes a distribution to approximate the…

Instrumentation and Methods for Astrophysics · Physics 2024-03-06 Alex Kolmus , Justin Janquart , Tomasz Baka , Twan van Laarhoven , Chris Van Den Broeck , Tom Heskes

We introduce AutoSpec, a neural network framework for discovering iterative spectral algorithms for large-scale numerical linear algebra and numerical optimization. Our self-supervised models adapt to input operators using coarse spectral…

Machine Learning · Computer Science 2026-02-11 Zihang Liu , Oleg Balabanov , Yaoqing Yang , Michael W. Mahoney

Retrieving the physical parameters from spectroscopic observations of exoplanets is key to understanding their atmospheric properties. Exoplanetary atmospheric retrievals are usually based on approximate Bayesian inference and rely on…

Earth and Planetary Astrophysics · Physics 2023-04-19 Malavika Vasist , François Rozet , Olivier Absil , Paul Mollière , Evert Nasedkin , Gilles Louppe

This study proposes an automated data mining framework based on autoencoders and experimentally verifies its effectiveness in feature extraction and data dimensionality reduction. Through the encoding-decoding structure, the autoencoder can…

Machine Learning · Computer Science 2024-12-04 Yaxin Liang , Xinshi Li , Xin Huang , Ziqi Zhang , Yue Yao

Simulation-Based Inference (SBI) is a promising Bayesian inference framework that alleviates the need for analytic likelihoods to estimate posterior distributions. Recent advances using neural density estimators in SBI algorithms have…

Instrumentation and Methods for Astrophysics · Physics 2022-07-13 Justine Zeghal , François Lanusse , Alexandre Boucaud , Benjamin Remy , Eric Aubourg

Autoencoders learn data representations (codes) in such a way that the input is reproduced at the output of the network. However, it is not always clear what kind of properties of the input data need to be captured by the codes. Kernel…

Machine Learning · Statistics 2018-07-24 Michael Kampffmeyer , Sigurd Løkse , Filippo M. Bianchi , Robert Jenssen , Lorenzo Livi

The massively parallel nature of biological information processing plays an important role for its superiority to human-engineered computing devices. In particular, it may hold the key to overcoming the von Neumann bottleneck that limits…

In this article, we propose an adapted sequential Monte Carlo approximate Bayesian computation (SMC-ABC) algorithm for network inference in coupled stochastic differential equations (SDEs) used for multivariate time series modeling. Our…

Methodology · Statistics 2025-08-27 Susanne Ditlevsen , Massimiliano Tamborrino , Irene Tubikanec

Data acquired from multi-channel sensors is a highly valuable asset to interpret the environment for a variety of remote sensing applications. However, low spatial resolution is a critical limitation for previous sensors and the constituent…

Computer Vision and Pattern Recognition · Computer Science 2018-07-17 Savas Ozkan , Berk Kaya , Gozde Bozdagi Akar

We present first experimental results on the novel BrainScaleS-2 neuromorphic architecture based on an analog neuro-synaptic core and augmented by embedded microprocessors for complex plasticity and experiment control. The high acceleration…

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