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Recent developments in high throughput profiling of individual neurons have spurred data driven exploration of the idea that there exist natural groupings of neurons referred to as cell types. The promise of this idea is that the immense…

Neurons and Cognition · Quantitative Biology 2019-11-14 Rohan Gala , Nathan Gouwens , Zizhen Yao , Agata Budzillo , Osnat Penn , Bosiljka Tasic , Gabe Murphy , Hongkui Zeng , Uygar Sümbül

Simulation-based inference (SBI) enables amortized Bayesian inference by first training a neural posterior estimator (NPE) on prior-simulator pairs, typically through low-dimensional summary statistics, which can then be cheaply reused for…

Machine Learning · Statistics 2026-02-11 Sherman Khoo , Dennis Prangle , Song Liu , Mark Beaumont

The study of plasticity in spiking neural networks is an active area of research. However, simulations that involve complex plasticity rules, dense connectivity/high synapse counts, complex neuron morphologies, or extended simulation times…

Neural and Evolutionary Computing · Computer Science 2024-12-05 Philipp Spilger , Eric Müller , Johannes Schemmel

Calcium imaging permits optical measurement of neural activity. Since intracellular calcium concentration is an indirect measurement of neural activity, computational tools are necessary to infer the true underlying spiking activity from…

Machine Learning · Statistics 2017-11-07 Artur Speiser , Jinyao Yan , Evan Archer , Lars Buesing , Srinivas C. Turaga , Jakob H. Macke

Reconstructing the structure of thin films and multilayers from measurements of scattered X-rays or neutrons is key to progress in physics, chemistry, and biology. However, finding all structures compatible with reflectometry data is…

Spiking neural networks (SNNs) offer a promising alternative to current artificial neural networks to enable low-power event-driven neuromorphic hardware. Spike-based neuromorphic applications require processing and extracting meaningful…

Neural and Evolutionary Computing · Computer Science 2019-06-24 Deboleena Roy , Priyadarshini Panda , Kaushik Roy

Network embedding represents nodes in a continuous vector space and preserves structure information from the Network. Existing methods usually adopt a "one-size-fits-all" approach when concerning multi-scale structure information, such as…

Machine Learning · Computer Science 2018-03-28 Lei Sang , Min Xu , Shengsheng Qian , Xindong Wu

A recent line of work has shown promise in using sparse autoencoders (SAEs) to uncover interpretable features in neural network representations. However, the simple linear-nonlinear encoding mechanism in SAEs limits their ability to perform…

Machine Learning · Computer Science 2025-01-31 Charles O'Neill , Alim Gumran , David Klindt

Predicting the dynamics of complex systems is crucial for various scientific and engineering applications. The accuracy of predictions depends on the model's ability to capture the intrinsic dynamics. While existing methods capture key…

Computational Engineering, Finance, and Science · Computer Science 2025-06-10 Ruikun Li , Jingwen Cheng , Huandong Wang , Qingmin Liao , Yong Li

Generative processes in biology and other fields often produce data that can be regarded as resulting from a composition of basic features. Here we present an unsupervised method based on autoencoders for inferring these basic features of…

Quantitative Methods · Quantitative Biology 2019-10-04 Matteo Negri , Davide Bergamini , Carlo Baldassi , Riccardo Zecchina , Christoph Feinauer

Depth estimation is an important computer vision task, useful in particular for navigation in autonomous vehicles, or for object manipulation in robotics. Here we solved it using an end-to-end neuromorphic approach, combining two…

Computer Vision and Pattern Recognition · Computer Science 2023-05-22 Ulysse Rançon , Javier Cuadrado-Anibarro , Benoit R. Cottereau , Timothée Masquelier

We introduce Sequential Neural Posterior Score Estimation (SNPSE), a score-based method for Bayesian inference in simulator-based models. Our method, inspired by the remarkable success of score-based methods in generative modelling,…

Machine Learning · Statistics 2024-06-04 Louis Sharrock , Jack Simons , Song Liu , Mark Beaumont

For stochastic models with intractable likelihood functions, approximate Bayesian computation offers a way of approximating the true posterior through repeated comparisons of observations with simulated model outputs in terms of a small set…

Machine Learning · Computer Science 2022-05-24 Carlo Albert , Simone Ulzega , Firat Ozdemir , Fernando Perez-Cruz , Antonietta Mira

Modelling the underlying mechanisms of neurodegenerative diseases demands methods that capture heterogeneous and spatially varying dynamics from sparse, high-dimensional neuroimaging data. Integrating partial differential equation (PDE)…

Image and Video Processing · Electrical Eng. & Systems 2025-09-19 Sanduni Pinnawala , Annabelle Hartanto , Ivor J. A. Simpson , Peter A. Wijeratne

We propose a masked self-supervised learning framework, called BRepMAE, for automatically extracting a valuable representation of the input computer-aided design (CAD) model to recognize its machining features. Representation learning is…

Graphics · Computer Science 2026-02-27 Can Yao , Kang Wu , Zuheng Zheng , Siyuan Xing , Xiao-Ming Fu

Many successful methods have been proposed for learning low dimensional representations on large-scale networks, while almost all existing methods are designed in inseparable processes, learning embeddings for entire networks even when only…

Machine Learning · Computer Science 2019-02-27 Ziyao Li , Liang Zhang , Guojie Song

Knowing the similarity between sets of data has a number of positive implications in training an effective model, such as assisting an informed selection out of known datasets favorable to model transfer or data augmentation problems with…

Machine Learning · Computer Science 2020-01-15 Inseok Hwang , Jinho Lee , Frank Liu , Minsik Cho

Accurate null depth retrieval is critical in nulling interferometry. However, achieving accurate null depth calibration is challenging due to various noise sources, instrumental imperfections, and the complexity of real observational…

Instrumentation and Methods for Astrophysics · Physics 2025-11-14 Baoyi Zeng , Marc-Antoine Martinod , Denis Defrère

Neuromorphic computing aims to replicate the brain's capabilities for energy efficient and parallel information processing, promising a solution to the increasing demand for faster and more efficient computational systems. Efficient…

Neural and Evolutionary Computing · Computer Science 2025-03-20 Gabriel Béna , Timo Wunderlich , Mahmoud Akl , Bernhard Vogginger , Christian Mayr , Hector Andres Gonzalez

Computer simulations have proven a valuable tool for understanding complex phenomena across the sciences. However, the utility of simulators for modelling and forecasting purposes is often restricted by low data quality, as well as…

Machine Learning · Statistics 2022-10-14 Daniel Ward , Patrick Cannon , Mark Beaumont , Matteo Fasiolo , Sebastian M Schmon