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Related papers: CellSeg1: Robust Cell Segmentation with One Traini…

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The accurate segmentation and tracking of cells in microscopy image sequences is an important task in biomedical research, e.g., for studying the development of tissues, organs or entire organisms. However, the segmentation of touching…

Computer Vision and Pattern Recognition · Computer Science 2020-12-10 Tim Scherr , Katharina Löffler , Moritz Böhland , Ralf Mikut

Semantic Segmentation combines two sub-tasks: the identification of pixel-level image masks and the application of semantic labels to those masks. Recently, so-called Foundation Models have been introduced; general models trained on very…

Computer Vision and Pattern Recognition · Computer Science 2023-10-03 David Balaban , Justin Medich , Pranay Gosar , Justin Hart

The segment anything model (SAM) was released as a foundation model for image segmentation. The promptable segmentation model was trained by over 1 billion masks on 11M licensed and privacy-respecting images. The model supports zero-shot…

Image segmentation is usually addressed by training a model for a fixed set of object classes. Incorporating additional classes or more complex queries later is expensive as it requires re-training the model on a dataset that encompasses…

Computer Vision and Pattern Recognition · Computer Science 2022-03-31 Timo Lüddecke , Alexander S. Ecker

The Segment Anything Model (SAM) is a powerful foundation model that introduced revolutionary advancements in natural image segmentation. However, its performance remains sub-optimal when delineating the intricate structure of biomedical…

Image and Video Processing · Electrical Eng. & Systems 2023-10-05 Xiangru Li , Yifei Zhang , Liang Zhao

The recently proposed segment anything model (SAM) has made a significant influence in many computer vision tasks. It is becoming a foundation step for many high-level tasks, like image segmentation, image caption, and image editing.…

Computer Vision and Pattern Recognition · Computer Science 2023-06-22 Xu Zhao , Wenchao Ding , Yongqi An , Yinglong Du , Tao Yu , Min Li , Ming Tang , Jinqiao Wang

Recent advancements in foundation models, such as the Segment Anything Model (SAM), have significantly impacted medical image segmentation, especially in retinal imaging, where precise segmentation is vital for diagnosis. Despite this…

Computer Vision and Pattern Recognition · Computer Science 2025-09-11 Zhihao Zhao , Yinzheng Zhao , Junjie Yang , Xiangtong Yao , Quanmin Liang , Shahrooz Faghihroohi , Kai Huang , Nassir Navab , M. Ali Nasseri

We introduce the Segment Anything (SA) project: a new task, model, and dataset for image segmentation. Using our efficient model in a data collection loop, we built the largest segmentation dataset to date (by far), with over 1 billion…

Computer Vision and Pattern Recognition · Computer Science 2023-04-06 Alexander Kirillov , Eric Mintun , Nikhila Ravi , Hanzi Mao , Chloe Rolland , Laura Gustafson , Tete Xiao , Spencer Whitehead , Alexander C. Berg , Wan-Yen Lo , Piotr Dollár , Ross Girshick

The medical imaging community generates a wealth of datasets, many of which are openly accessible and annotated for specific diseases and tasks such as multi-organ or lesion segmentation. Current practices continue to limit model training…

Image and Video Processing · Electrical Eng. & Systems 2024-01-09 Constantin Ulrich , Fabian Isensee , Tassilo Wald , Maximilian Zenk , Michael Baumgartner , Klaus H. Maier-Hein

Following the successful paradigm shift of large language models, leveraging pre-training on a massive corpus of data and fine-tuning on different downstream tasks, generalist models have made their foray into computer vision. The…

Image and Video Processing · Electrical Eng. & Systems 2025-11-21 Andrea Moglia , Matteo Leccardi , Matteo Cavicchioli , Alice Maccarini , Marco Marcon , Luca Mainardi , Pietro Cerveri

Curating fully annotated datasets for medical image segmentation is labour-intensive and expertise-demanding. To alleviate this problem, prior studies have explored scribble annotations for weakly supervised segmentation. Existing solutions…

Computer Vision and Pattern Recognition · Computer Science 2026-05-08 Ke Zhang , Bomin Wang , Hangqi Zhou , Xiahai Zhuang

Segmentation is an important analysis task for biomedical images, enabling the study of individual organelles, cells or organs. Deep learning has massively improved segmentation methods, but challenges remain in generalization to new…

Computer Vision and Pattern Recognition · Computer Science 2025-06-03 Carolin Teuber , Anwai Archit , Constantin Pape

We introduce CellSegmenter, a structured deep generative model and an amortized inference framework for unsupervised representation learning and instance segmentation tasks. The proposed inference algorithm is convolutional and…

Computer Vision and Pattern Recognition · Computer Science 2020-11-26 Luca D'Alessio , Mehrtash Babadi

Multi-organ segmentation has extensive applications in many clinical applications. To segment multiple organs of interest, it is generally quite difficult to collect full annotations of all the organs on the same images, as some medical…

Computer Vision and Pattern Recognition · Computer Science 2020-08-18 Rui Huang , Yuanjie Zheng , Zhiqiang Hu , Shaoting Zhang , Hongsheng Li

Accurate segmentation of 3-D cell nuclei in microscopy images is essential for the study of nuclear organization, gene expression, and cell morphodynamics. Current image segmentation methods are challenged by the complexity and variability…

Image and Video Processing · Electrical Eng. & Systems 2022-03-18 Sundaresh Ram , Jeffrey J. Rodriguez

Tracking cells and detecting mitotic events in time-lapse microscopy image sequences is a crucial task in biomedical research. However, it remains highly challenging due to dividing objects, low signal-tonoise ratios, indistinct boundaries,…

Computer Vision and Pattern Recognition · Computer Science 2025-09-15 Zhu Chen , Mert Edgü , Er Jin , Johannes Stegmaier

A central challenge for the task of semantic segmentation is the prohibitive cost of obtaining dense pixel-level annotations to supervise model training. In this work, we show that in order to achieve a good level of segmentation…

Computer Vision and Pattern Recognition · Computer Science 2021-04-16 Gyungin Shin , Weidi Xie , Samuel Albanie

Reliable classification and detection of certain medical conditions, in images, with state-of-the-art semantic segmentation networks, require vast amounts of pixel-wise annotation. However, the public availability of such datasets is…

Computer Vision and Pattern Recognition · Computer Science 2023-03-17 Erik Ostrowski , Bharath Srinivas Prabakaran , Muhammad Shafique

In digital pathology, precise nuclei segmentation is pivotal yet challenged by the diversity of tissue types, staining protocols, and imaging conditions. Recently, the segment anything model (SAM) revealed overwhelming performance in…

Image and Video Processing · Electrical Eng. & Systems 2024-02-27 Zhen Chen , Qing Xu , Xinyu Liu , Yixuan Yuan

Volumetric cell segmentation in fluorescence microscopy images is important to study a wide variety of cellular processes. Applications range from the analysis of cancer cells to behavioral studies of cells in the embryonic stage. Like in…

Image and Video Processing · Electrical Eng. & Systems 2022-11-29 Royden Wagner , Karl Rohr