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Accurate nuclei segmentation in microscopy whole slide images (WSIs) remains challenging due to variability in staining, imaging conditions, and tissue morphology. We propose CellGenNet, a knowledge distillation framework for robust…

Computer Vision and Pattern Recognition · Computer Science 2025-11-20 Srijan Ray , Bikesh K. Nirala , Jason T. Yustein , Sundaresh Ram

The Segment Anything Model (SAM) is a foundation model for general image segmentation. Although it exhibits impressive performance predominantly on natural images, understanding its robustness against various image perturbations and domains…

Computer Vision and Pattern Recognition · Computer Science 2023-05-25 Yuqing Wang , Yun Zhao , Linda Petzold

Most state-of-the-art techniques for medical image segmentation rely on deep-learning models. These models, however, are often trained on narrowly-defined tasks in a supervised fashion, which requires expensive labeled datasets. Recent…

Image and Video Processing · Electrical Eng. & Systems 2023-10-04 Heejong Kim , Victor Ion Butoi , Adrian V. Dalca , Daniel J. A. Margolis , Mert R. Sabuncu

Semi-supervised learning, which leverages both annotated and unannotated data, is an efficient approach for medical image segmentation, where obtaining annotations for the whole dataset is time-consuming and costly. Traditional…

Computer Vision and Pattern Recognition · Computer Science 2025-02-06 Ruizhe Li , Grazziela Figueredo , Dorothee Auer , Rob Dineen , Paul Morgan , Xin Chen

Recently, automated medical image segmentation methods based on deep learning have achieved great success. However, they heavily rely on large annotated datasets, which are costly and time-consuming to acquire. Few-shot learning aims to…

Artificial Intelligence · Computer Science 2024-08-20 Jiayu Huo , Ruiqiang Xiao , Haotian Zheng , Yang Liu , Sebastien Ourselin , Rachel Sparks

In medical image analysis, achieving fast, efficient, and accurate segmentation is essential for automated diagnosis and treatment. Although recent advancements in deep learning have significantly improved segmentation accuracy, current…

Computer Vision and Pattern Recognition · Computer Science 2024-12-02 Zhi Li , Kai Zhao , Yaqi Wang , Shuai Wang

Accurate robot segmentation is a fundamental capability for robotic perception. It enables precise visual servoing for VLA systems, scalable robot-centric data augmentation, accurate real-to-sim transfer, and reliable safety monitoring in…

Computer Vision and Pattern Recognition · Computer Science 2026-03-31 Haiyang Mei , Qiming Huang , Hai Ci , Mike Zheng Shou

Cell segmentation is a fundamental task for computational biology analysis. Identifying the cell instances is often the first step in various downstream biomedical studies. However, many cell segmentation algorithms, including the recently…

Computer Vision and Pattern Recognition · Computer Science 2022-12-08 Gihun Lee , Sangmook Kim , Joonkee Kim , Se-Young Yun

We present MSeg, a composite dataset that unifies semantic segmentation datasets from different domains. A naive merge of the constituent datasets yields poor performance due to inconsistent taxonomies and annotation practices. We reconcile…

Computer Vision and Pattern Recognition · Computer Science 2021-12-28 John Lambert , Zhuang Liu , Ozan Sener , James Hays , Vladlen Koltun

The lack of sufficient annotated image data is a common issue in medical image segmentation. For some organs and densities, the annotation may be scarce, leading to poor model training convergence, while other organs have plenty of…

Image and Video Processing · Electrical Eng. & Systems 2021-09-22 Anastasia Makarevich , Azade Farshad , Vasileios Belagiannis , Nassir Navab

The Segment Anything Model (SAM) exhibits a capability to segment a wide array of objects in natural images, serving as a versatile perceptual tool for various downstream image segmentation tasks. In contrast, medical image segmentation…

Computer Vision and Pattern Recognition · Computer Science 2023-08-29 Yizhe Zhang , Tao Zhou , Shuo Wang , Ye Wu , Pengfei Gu , Danny Z. Chen

While modern segmentation models often prioritize performance over practicality, we advocate a design philosophy prioritizing simplicity and efficiency, and attempted high performance segmentation model design. This paper presents…

Image and Video Processing · Electrical Eng. & Systems 2025-06-17 Xiang Yu , Yayan Chen , Guannan He , Qing Zeng , Yue Qin , Meiling Liang , Dandan Luo , Yimei Liao , Zeyu Ren , Cheng Kang , Delong Yang , Bocheng Liang , Bin Pu , Ying Yuan , Shengli Li

The Segment Anything Model (SAM) family has become a widely adopted vision foundation model, but its ability to control segmentation granularity remains limited. Users often need to refine results manually - by adding more prompts or…

Computer Vision and Pattern Recognition · Computer Science 2025-11-18 Junwei Yu , Trevor Darrell , XuDong Wang

Accurate cell counting is essential in various biomedical research and clinical applications, including cancer diagnosis, stem cell research, and immunology. Manual counting is labor-intensive and error-prone, motivating automation through…

Computer Vision and Pattern Recognition · Computer Science 2025-11-25 Abdurahman Ali Mohammed , Catherine Fonder , Ying Wei , Wallapak Tavanapong , Donald S Sakaguchi , Qi Li , Surya K. Mallapragada

Automatic image segmentation is a critical component of medical image analysis, and hence quantifying segmentation performance is crucial. Challenges in medical image segmentation are mainly due to spatial variations of regions to be…

Image and Video Processing · Electrical Eng. & Systems 2021-09-09 Ammu R , Neelam Sinha

Developing clinically useful cell-level analysis tools in digital pathology remains challenging due to limitations in dataset granularity, inconsistent annotations, high computational demands, and difficulties integrating new technologies…

Computer Vision and Pattern Recognition · Computer Science 2025-12-02 Nikita Shvetsov , Thomas K. Kilvaer , Masoud Tafavvoghi , Anders Sildnes , Kajsa Møllersen , Lill-Tove Rasmussen Busund , Lars Ailo Bongo

Cell and nucleus segmentation are fundamental tasks for quantitative bioimage analysis. Despite progress in recent years, biologists and other domain experts still require novel algorithms to handle increasingly large and complex real-world…

Computer Vision and Pattern Recognition · Computer Science 2024-08-29 Thibaut Goldsborough , Ben Philps , Alan O'Callaghan , Fiona Inglis , Leo Leplat , Andrew Filby , Hakan Bilen , Peter Bankhead

Cell instance segmentation models trained on cell-specific datasets suffer severe performance drops on out-of-distribution cell types, while interactive foundation models overcome this through per-instance prompting at a cost that is…

Computer Vision and Pattern Recognition · Computer Science 2026-05-29 Sanghyun Jo , Seo Jin Lee , Seohyung Hong , Yoorim Gang , Hyeongsub Kim , Hyungseok Seo , Kyungsu Kim

Semantic segmentation is a crucial task in medical imaging. Although supervised learning techniques have proven to be effective in performing this task, they heavily depend on large amounts of annotated training data. The recently…

Computer Vision and Pattern Recognition · Computer Science 2024-11-20 Ron Keuth , Lasse Hansen , Maren Balks , Ronja Jäger , Anne-Nele Schröder , Ludger Tüshaus , Mattias Heinrich

Automatic segmentation of medical images is crucial in modern clinical workflows. The Segment Anything Model (SAM) has emerged as a versatile tool for image segmentation without specific domain training, but it requires human prompts and…

Computer Vision and Pattern Recognition · Computer Science 2024-05-16 Yunxiang Li , Bowen Jing , Zihan Li , Jing Wang , You Zhang
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