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Semantic segmentation of remote sensing (RS) images is a challenging yet essential task with broad applications. While deep learning, particularly supervised learning with large-scale labeled datasets, has significantly advanced this field,…

Computer Vision and Pattern Recognition · Computer Science 2024-12-02 Bin Wang , Fei Deng , Shuang Wang , Wen Luo , Zhixuan Zhang , Peifan Jiang

Whole slide images (WSIs) enable weakly supervised prognostic modeling via multiple instance learning (MIL). Spatial transcriptomics (ST) preserves in situ gene expression, providing a spatial molecular context that complements morphology.…

Computer Vision and Pattern Recognition · Computer Science 2026-02-16 Lihe Liu , Xiaoxi Pan , Yinyin Yuan , Lulu Shang

Single-cell spatial transcriptomics (ST) offers a unique approach to measuring gene expression profiles and spatial cell locations simultaneously. However, most existing ST methods assume that cells in closer spatial proximity exhibit more…

Genomics · Quantitative Biology 2025-06-10 Xiongtao Xiao , Xiaofeng Chen , Feiyan Jiang , Songming Zhang , Wenming Cao , Cheng Tan , Zhangyang Gao , Zhongshan Li

Spatial transcriptomics (ST) is an emerging technology that enables medical computer vision scientists to automatically interpret the molecular profiles underlying morphological features. Currently, however, most deep learning-based ST…

Computer Vision and Pattern Recognition · Computer Science 2024-12-05 Junchao Zhu , Ruining Deng , Tianyuan Yao , Juming Xiong , Chongyu Qu , Junlin Guo , Siqi Lu , Mengmeng Yin , Yu Wang , Shilin Zhao , Haichun Yang , Yuankai Huo

Spatial Transcriptomics enables mapping of gene expression within its native tissue context, but current platforms measure only a limited set of genes due to experimental constraints and excessive costs. To overcome this, computational…

Genomics · Quantitative Biology 2025-11-20 Amit Kumar , Maninder Kaur , Raghvendra Mall , Sukrit Gupta

Distribution Regression (DR) on stochastic processes describes the learning task of regression on collections of time series. Path signatures, a technique prevalent in stochastic analysis, have been used to solve the DR problem. Recent…

Machine Learning · Computer Science 2024-10-15 Andrew Alden , Carmine Ventre , Blanka Horvath

Existing self-supervised learning (SSL) methods primarily learn object-invariant representations but often neglect the spatial structure and relationships among object parts. To address this limitation, we introduce Spatial Prediction (SP),…

Computer Vision and Pattern Recognition · Computer Science 2026-05-12 Yang Shen , Yusen Cai , Weronika Hryniewska-Guzik , Qing Lin , Mengmi Zhang

Stereo image super-resolution (SSR) aims to enhance high-resolution details by leveraging information from stereo image pairs. However, existing stereo super-resolution (SSR) upsampling methods (e.g., pixel shuffle) often overlook…

Image and Video Processing · Electrical Eng. & Systems 2025-07-08 Yi Liu , Xinyi Liu , Yi Wan , Panwang Xia , Qiong Wu , Yongjun Zhang

Image-based sequencing of mRNA makes it possible to see where in a tissue sample a given gene is active, and thus discern large numbers of different cell types in parallel. This is crucial for gaining a better understanding of tissue…

Quantitative Methods · Quantitative Biology 2018-02-27 Gabriele Partel , Giorgia Milli , Carolina Wählby

Unsupervised domain adaptation (UDA) has become increasingly prevalent in scene text recognition (STR), especially where training and testing data reside in different domains. The efficacy of existing UDA approaches tends to degrade when…

Computer Vision and Pattern Recognition · Computer Science 2025-04-15 Kha Nhat Le , Hoang-Tuan Nguyen , Hung Tien Tran , Thanh Duc Ngo

This paper demonstrates that spatial information can be used to learn interpretable representations in medical images using Self-Supervised Learning (SSL). Our proposed method, ISImed, is based on the observation that medical images exhibit…

Computer Vision and Pattern Recognition · Computer Science 2024-10-23 Nabil Jabareen , Dongsheng Yuan , Sören Lukassen

In recent years, the advent of spatial transcriptomics (ST) technology has unlocked unprecedented opportunities for delving into the complexities of gene expression patterns within intricate biological systems. Despite its transformative…

Image and Video Processing · Electrical Eng. & Systems 2024-07-12 Wenwen Min , Zhiceng Shi , Jun Zhang , Jun Wan , Changmiao Wang

Spatial transcriptomics (ST) measures gene expression at fine-grained spatial resolution, offering insights into tissue molecular landscapes. Previous methods for spatial gene expression prediction typically crop spots of interest from…

Computer Vision and Pattern Recognition · Computer Science 2025-11-26 Ruikun Zhang , Yan Yang , Liyuan Pan

Spatial studies of transcriptome provide biologists with gene expression maps of heterogeneous and complex tissues. However, most experimental protocols for spatial transcriptomics suffer from the need to select beforehand a small fraction…

Machine Learning · Computer Science 2019-05-08 Romain Lopez , Achille Nazaret , Maxime Langevin , Jules Samaran , Jeffrey Regier , Michael I. Jordan , Nir Yosef

Spatial transcriptomics (ST) bridges gene expression and tissue morphology but faces clinical adoption barriers due to technical complexity and prohibitive costs. While computational methods predict gene expression from H&E-stained…

Computer Vision and Pattern Recognition · Computer Science 2025-11-20 Ziqiao Weng , Yaoyu Fang , Jiahe Qian , Xinkun Wang , Lee AD Cooper , Weidong Cai , Bo Zhou

In computational pathology, deep learning (DL) models for tasks such as segmentation or tissue classification are known to suffer from domain shifts due to different staining techniques. Stain adaptation aims to reduce the generalization…

Image and Video Processing · Electrical Eng. & Systems 2024-07-04 Daniel Reisenbüchler , Lucas Luttner , Nadine S. Schaadt , Friedrich Feuerhake , Dorit Merhof

The integration of spatial multi-omics data from single tissues is crucial for advancing biological research. However, a significant data imbalance impedes progress: while spatial transcriptomics data is relatively abundant, spatial…

Artificial Intelligence · Computer Science 2026-02-06 Zhaorui Jiang , Yingfang Yuan , Lei Hu , Wei Pang

State-of-the-art methods for Convolutional Sparse Coding usually employ Fourier-domain solvers in order to speed up the convolution operators. However, this approach is not without shortcomings. For example, Fourier-domain representations…

Image and Video Processing · Electrical Eng. & Systems 2019-09-04 Jinhui Xiong , Peter Richtárik , Wolfgang Heidrich

Spatial transcriptomics clustering is pivotal for identifying cell subpopulations by leveraging spatial location information. While recent graph-based methods modeling cell-cell interactions have improved clustering accuracy, they remain…

Machine Learning · Computer Science 2026-01-21 Chenkai Guo , Yikai Zhu , Renxiang Guan , Jinli Ma , Siwei Wang , Ke Liang , Guangdun Peng , Dayu Hu

This work studies the robust subspace tracking (ST) problem. Robust ST can be simply understood as a (slow) time-varying subspace extension of robust PCA. It assumes that the true data lies in a low-dimensional subspace that is either fixed…

Machine Learning · Computer Science 2022-09-01 Praneeth Narayanamurthy , Namrata Vaswani
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