Related papers: Bayesian feature selection in joint models with ap…
Cardiovascular diseases (CVD), including atherosclerosis CVD (ASCVD), are multifactorial diseases that present a major economic and social burden worldwide. Tremendous efforts have been made to understand traditional risk factors for ASCVD,…
Cardiovascular disease (CVD) cohort studies collect longitudinal data on numerous CVD risk factors including body mass index (BMI), systolic blood pressure (SBP), diastolic blood pressure (DBP), glucose, and total cholesterol. The commonly…
We introduce a novel Bayesian approach for jointly modeling longitudinal cardiovascular disease (CVD) risk factor trajectories, medication use, and time-to-events. Our methodology incorporates longitudinal risk factor trajectories into the…
Cardiovascular diseases (CVD) remain a leading health concern and contribute significantly to global mortality rates. While clinical advancements have led to a decline in CVD mortality, accurately identifying individuals who could benefit…
We introduce a statistical framework for combining data from multiple large longitudinal cardiovascular cohorts to enable the study of long-term cardiovascular health starting in early adulthood. Using data from seven cohorts belonging to…
In many clinical and epidemiological studies, collecting longitudinal measurements together with time-to-event outcomes is essential. Accurately estimating the association between longitudinal markers and event risks, as well as identifying…
An accurate assessment of the cardiovascular system and prediction of cardiovascular diseases (CVDs) are crucial. Measured cardiac blood flow data provide insights about patient-specific hemodynamics, where many specialized techniques have…
An important issue in joint modelling for outcomes and longitudinal risk factors in cohort studies is to have an accurate assessment of events. Events determined based on ICD-9 codes can be very inaccurate, in particular for cardiovascular…
Causal mediation analysis of observational data is an important tool for investigating the potential causal effects of medications on disease-related risk factors, and on time-to-death (or disease progression) through these risk factors.…
Cardiovascular disease (CVD) continues to be the major cause of death globally, calling for predictive models that not only handle diverse and high-dimensional biomedical signals but also maintain interpretability and privacy. We create a…
Cardiovascular diseases (CVDs) are one of the most common chronic illnesses that affect peoples health. Early detection of CVDs can reduce mortality rates by preventing or reducing the severity of the disease. Machine learning algorithms…
The point of care services and medication have become simpler with efficient consumer electronics devices in a smart healthcare system. Cardiovascular disease is a critical illness which causes heart failure, and early and prompt…
Cardiovascular disease and chronic kidney disease are major complications of diabetes, leading to high morbidity and mortality. Early detection of these conditions is critical, yet traditional diagnostic markers often lack sensitivity in…
Background: Multiple medical and non-medical stressors, along with the complicity of their exposure pathways, have posted significant challenges to the epidemiological interpretation of the non-communicable diseases, including…
Background: Cardiovascular diseases (CVDs) are among the leading causes of death worldwide. Predictive scores providing personalised risk of developing CVD are increasingly used in clinical practice. Most scores, however, utilise a…
Observational cohort data is an important source of information for understanding the causal effects of treatments on survival and the degree to which these effects are mediated through changes in disease-related risk factors. However,…
Machine learning models have the potential to identify cardiovascular diseases (CVDs) early and accurately in primary healthcare settings, which is crucial for delivering timely treatment and management. Although population-based CVD risk…
Hypertension is a highly prevalent chronic medical condition and a strong risk factor for cardiovascular disease (CVD), as it accounts for more than $45\%$ of CVD. The relation between blood pressure (BP) and its risk factors cannot be…
AIMS. This study compared the performance of deep learning extensions of survival analysis models with traditional Cox proportional hazards (CPH) models for deriving cardiovascular disease (CVD) risk prediction equations in national health…
In this work, a novel approach is proposed for joint analysis of high dimensional time-resolved cardiac motion features obtained from segmented cardiac MRI and low dimensional clinical risk factors to improve survival prediction in heart…