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Given the high incidence of cardio and cerebrovascular diseases (CVD), and its association with morbidity and mortality, its prevention is a major public health issue. A high level of blood pressure is a well-known risk factor for these…

Competing risk models are survival models with several events of interest acting in competition and whose occurrence is only observed for the event that occurs first in time. This paper presents a Bayesian approach to these models in which…

Cardiovascular diseases (CVDs) are a main cause of mortality globally, accounting for 31% of all deaths. This study involves a cardiovascular disease (CVD) dataset comprising 68,119 records to explore the influence of numerical (age,…

Machine Learning · Computer Science 2025-07-30 Risshab Srinivas Ramesh , Roshani T S Udupa , Monisha J , Kushi K K S

Multiple long-term conditions (MLTC) are increasingly observed in clinical practice globally. Clustering methods to group diseases into commonly co-occurring clusters have been of interest for further understanding of how MLTC group…

Applications · Statistics 2026-03-02 James Rafferty , Keith R Abrams , Munir Pirmohamed , Mark Davies , Rhiannon K Owen

Cross-validation (CV) is a widely-used method of predictive assessment based on repeated model fits to different subsets of the available data. CV is applicable in a wide range of statistical settings. However, in cases where data are not…

Methodology · Statistics 2025-04-23 Alex Cooper , Aki Vehtari , Catherine Forbes

Coronary heart disease (CHD) caused by hardening of artery walls due to cholesterol known as atherosclerosis is responsible for large number of deaths world-wide. The disease progression is slow, asymptomatic and may lead to sudden cardiac…

Machine Learning · Computer Science 2015-02-03 V. Sree Hari Rao , M. Naresh Kumar

Accurate prediction of cardiovascular disease (CVD) risk is crucial for healthcare institutions. This study addresses the growing prevalence of diabetes and its strong link to heart disease by proposing an efficient CVD risk prediction…

Machine Learning · Computer Science 2025-11-10 Esha Chowdhury

We consider applying Bayesian Variable Selection Regression, or BVSR, to genome-wide association studies and similar large-scale regression problems. Currently, typical genome-wide association studies measure hundreds of thousands, or…

Applications · Statistics 2011-10-28 Yongtao Guan , Matthew Stephens

Cardio/cerebrovascular diseases (CVD) have become one of the major health issue in our societies. But recent studies show that the present pathology tests to detect CVD are ineffectual as they do not consider different stages of platelet…

Joint models for longitudinal biomarkers and time-to-event data are widely used in longitudinal studies. Many joint modeling approaches have been proposed to deal with different types of longitudinal biomarkers and survival outcomes.…

Methodology · Statistics 2016-09-27 Molei Liu , Jiehuan Sun , Jose D. Herazo-Maya , Naftali Kaminski , Hongyu Zhao

In the field of cardio-thoracic surgery, valve function is monitored over time after surgery. The motivation for our research comes from a study which includes patients who received a human tissue valve in the aortic position. These…

Cardiovascular diseases state as one of the greatest risks of death for the general population. Late detection in heart diseases highly conditions the chances of survival for patients. Age, sex, cholesterol level, sugar level, heart rate,…

Heart Disease has become one of the most serious diseases that has a significant impact on human life. It has emerged as one of the leading causes of mortality among the people across the globe during the last decade. In order to prevent…

Machine Learning · Computer Science 2022-06-08 Muhammad Salman Pathan , Avishek Nag , Muhammad Mohisn Pathan , Soumyabrata Dev

Cohort effects are important factors in determining the evolution of human mortality for certain countries. Extensions of dynamic mortality models with cohort features have been proposed in the literature to account for these factors under…

Statistical Finance · Quantitative Finance 2019-02-20 Man Chung Fung , Gareth W. Peters , Pavel V. Shevchenko

Coronary Artery Disease (CAD) is one of the leading causes of death worldwide, and so it is very important to correctly diagnose patients with the disease. For medical diagnosis, machine learning is a useful tool, however features and…

Machine Learning · Computer Science 2018-12-10 Ali Bou Nassif , Omar Mahdi , Qassim Nasir , Manar Abu Talib , Mohammad Azzeh

In today's world, a massive amount of data is available in almost every sector. This data has become an asset as we can use this enormous amount of data to find information. Mainly health care industry contains many data consisting of…

Machine Learning · Computer Science 2022-03-10 Hafsa Binte Kibria , Abdul Matin

Medical studies for chronic disease are often interested in the relation between longitudinal risk factor profiles and individuals' later life disease outcomes. These profiles may typically be subject to intermediate structural changes due…

Applications · Statistics 2023-08-22 Sandra Keizer , Zhuozhao Zhan , Vasan S. Ramachandran , Edwin R. van den Heuvel

Within-individual variability of health indicators measured over time is becoming commonly used to inform about disease progression. Simple summary statistics (e.g. the standard deviation for each individual) are often used but they are not…

Cardiovascular diseases (CVDs) encompass a group of disorders affecting the heart and blood vessels, including conditions such as coronary artery disease, heart failure, stroke, and hypertension. In cardiovascular diseases, heart failure is…

Artificial Intelligence · Computer Science 2024-07-12 Ershadul Haque , Manoranjan Paul , Faranak Tohidi

There have been significant efforts devoted to solving the longevity risk given that a continuous growth in population ageing has become a severe issue for many developed countries over the past few decades. The Cairns-Blake-Dowd (CBD)…

Applications · Statistics 2024-12-30 Ka Kin Lam , Bo Wang