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Is it possible to make statistical inference broadly accessible to non-statisticians without sacrificing mathematical rigor or inference quality? This paper describes BayesDB, a probabilistic programming platform that aims to enable users…

Artificial Intelligence · Computer Science 2015-12-17 Vikash Mansinghka , Richard Tibbetts , Jay Baxter , Pat Shafto , Baxter Eaves

The sudden appearance of modern machine learning (ML) phenomena like double descent and benign overfitting may leave many classically trained statisticians feeling uneasy -- these phenomena appear to go against the very core of statistical…

Machine Learning · Statistics 2024-09-30 Alicia Curth

We study the performance of classical and quantum machine learning (ML) models in predicting outcomes of physical experiments. The experiments depend on an input parameter $x$ and involve execution of a (possibly unknown) quantum process…

Quantum Physics · Physics 2021-05-19 Hsin-Yuan Huang , Richard Kueng , John Preskill

Data-driven techniques are increasingly used to replace electronic-structure calculations of matter. In this context, a relevant question is whether machine learning (ML) should be applied directly to predict the desired properties or be…

We propose a Bayesian approach for both medical inquiry and disease inference, the two major phases in differential diagnosis. Unlike previous work that simulates data from given probabilities and uses ML algorithms on them, we directly use…

Artificial Intelligence · Computer Science 2021-10-26 Hong Guan , Chitta Baral

As artificial intelligence and machine learning tools become more accessible, and scientists face new obstacles to data collection (e.g., rising costs, declining survey response rates), researchers increasingly use predictions from…

Machine Learning · Statistics 2025-12-08 Stephen Salerno , Kentaro Hoffman , Awan Afiaz , Anna Neufeld , Tyler H. McCormick , Jeffrey T. Leek

Various AI models are increasingly being considered as part of clinical decision-support tools. However, the trustworthiness of such models is rarely considered. Clinicians are more likely to use a model if they can understand and trust its…

Artificial Intelligence · Computer Science 2020-03-09 Evangelia Kyrimi , Somayyeh Mossadegh , Nigel Tai , William Marsh

Clinical researchers often select among and evaluate risk prediction models using standard machine learning metrics based on confusion matrices. However, if these models are used to allocate interventions to patients, standard metrics…

Machine Learning · Statistics 2020-06-03 Alejandro Schuler , Aashish Bhardwaj , Vincent Liu

Context: Software engineering has a problem in that when we empirically evaluate competing prediction systems we obtain conflicting results. Objective: To reduce the inconsistency amongst validation study results and provide a more formal…

Software Engineering · Computer Science 2021-01-15 Martin Shepperd , Stephen G. MacDonell

Our paper deals with inferring simulator-based statistical models given some observed data. A simulator-based model is a parametrized mechanism which specifies how data are generated. It is thus also referred to as generative model. We…

Machine Learning · Statistics 2016-01-01 Michael U. Gutmann , Jukka Corander

This paper attempts to answer a "simple question" in building predictive models using machine learning algorithms. Although diagnostic and predictive models for various diseases have been proposed using data from large cohort studies and…

Machine Learning · Computer Science 2024-09-04 Isao Goto

We propose a method to debias estimators based on U-statistics with Machine Learning (ML) first-steps. Standard plug-in estimators often suffer from regularization and model-selection biases, producing invalid inferences. We show that…

Econometrics · Economics 2025-10-09 Juan Carlos Escanciano , Joël Robert Terschuur

The emergence of a variety of Machine Learning (ML) approaches for travel mode choice prediction poses an interesting question to transport modellers: which models should be used for which applications? The answer to this question goes…

Interpretable machine learning has become a strong competitor for traditional black-box models. However, the possible loss of the predictive performance for gaining interpretability is often inevitable, putting practitioners in a dilemma of…

Machine Learning · Computer Science 2019-05-13 Tong Wang , Qihang Lin

Machine Learning (ML) is increasingly used across many disciplines with impressive reported results. However, recent studies suggest published performance of ML models are often overoptimistic. Validity concerns are underscored by findings…

Machine Learning · Computer Science 2024-07-15 Pouria Saidi , Gautam Dasarathy , Visar Berisha

It is argued that the Calibrated Bayesian (CB) approach to statistical inference capitalizes on the strength of Bayesian and frequentist approaches to statistical inference. In the CB approach, inferences under a particular model are…

Methodology · Statistics 2011-08-10 Roderick Little

When interpreting A/B tests, we typically focus only on the statistically significant results and take them by face value. This practice, termed post-selection inference in the statistical literature, may negatively affect both point…

Applications · Statistics 2021-06-01 Alex Deng , Yicheng Li , Jiannan Lu , Vivek Ramamurthy

Multivariate meta-analysis is gaining prominence in evidence synthesis research because it enables simultaneous synthesis of multiple correlated outcome data, and random-effects models have generally been used for addressing between-studies…

Methodology · Statistics 2021-07-14 Hisashi Noma , Kengo Nagashima , Toshi A. Furukawa

Explainable boosting machines (EBMs) are popular "glass-box" models that learn a set of univariate functions using boosting trees. These achieve explainability through visualizations of each feature's effect. However, unlike linear model…

Machine Learning · Statistics 2026-03-31 Haimo Fang , Kevin Tan , Jonathan Pipping-Gamon , Giles Hooker

Double machine learning is a statistical method for leveraging complex black-box models to construct approximately unbiased treatment effect estimates given observational data with high-dimensional covariates, under the assumption of a…

Machine Learning · Statistics 2022-06-03 Nitai Fingerhut , Matteo Sesia , Yaniv Romano
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