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Diffraction unlimited super-resolution imaging critically depends on the switching of fluorophores between at least two states, often induced using intense laser light and special buffers. The high illumination power or UV light required…

Interferometers are widely used in imaging technologies to achieve enhanced spatial resolution, but require that the incoming photons be indistinguishable. In previous work, we built and analyzed color erasure detectors which expand the…

Super-resolution light microscopy overcomes the physical barriers due to light diffraction, allowing for the observation of otherwise indistinguishable subcellular entities. However, the specific acquisition conditions required by…

Fluorescence spectroscopy is an image correlation technique to analyze and characterize the molecular dynamics from a sequence of fluorescence images. Many image correlation techniques have been developed for different applications [1]. But…

Quantitative Methods · Quantitative Biology 2017-10-24 C. Chen , P. Paul-Gilloteaux , T. Vignaud , J. Salamero , F. Waharte

Previous stochastic localization-based super-resolution techniques are largely limited by the labeling density and the fidelity to the morphology of specimen. We report on an optical super-resolution imaging scheme implementing joint…

Thermal motion gives rise to fluctuations in free surfaces; the propagation of the thermally excited waves on such surfaces depends on the mechanical properties of the medium. Their measurement can therefore provide information on those…

Hyperspectral images enable precise identification of ground objects by capturing their spectral signatures with fine spectral resolution.While high spatial resolution further enhances this capability, increasing spatial resolution through…

Image and Video Processing · Electrical Eng. & Systems 2024-10-25 Ankur Garg , Meenakshi Sarkar , S. Manthira Moorthi , Debajyoti Dhar

Extreme gravitational lensing and relativistic frequency shifts, combined together, imply that radiation emitted from a black hole's vicinity can echo at different frequencies and times, leading to spectrotemporal correlations in observed…

High Energy Astrophysical Phenomena · Physics 2025-08-19 Sreehari Harikesh , Shahar Hadar , Doron Chelouche

Hyperspectral imaging aims at providing information on both the spatial and the spectral distribution of light, with high resolution. However, state-of-the-art protocols are characterized by an intrinsic trade-off imposing to sacrifice…

Optics · Physics 2024-07-22 Gianlorenzo Massaro , Francesco V. Pepe , Milena D'Angelo

Imaging below the diffraction limit is always a public interest because of the restricted resolution of conventional imaging systems. To beat the limit, evanescent harmonics decaying in space must participate in the imaging process. Here,…

Optics · Physics 2019-10-02 Tie-Jun Huang , Li-Zheng Yin , Ya Shuang , Jiang-Yu Liu , Yunhua Tan , Pu-Kun Liu

Several recent studies advocate the use of spectral discriminators, which evaluate the Fourier spectra of images for generative modeling. However, the effectiveness of the spectral discriminators is not well interpreted yet. We tackle this…

Computer Vision and Pattern Recognition · Computer Science 2023-08-17 Xin Luo , Yunan Zhu , Shunxin Xu , Dong Liu

We report, for the first time, a multi-confocal Fluorescence Correlation Spectroscopy (mFCS) technique which allows parallel measurements at different locations, by combining a Spatial Light Modulator (SLM), with an Electron Multiplying-CCD…

Optical scattering presents a major obstacle to high resolution imaging in biological tissue and other turbid media. Conventional photoacoustic imaging can partially overcome this obstacle, enabling imaging of optical absorption in the…

The ability to determine precisely the separation of two frequencies is fundamental to spectroscopy, yet the resolution limit poses a critical challenge: distinguishing two incoherent signals becomes impossible when their frequencies are…

Quantum Physics · Physics 2025-12-29 Qingyun Cao , Genko T. Genov , Yaoming Chu , Jianming Cai , Yu Liu , Alex Retzker , Fedor Jelezko

In traditional optical imaging systems, the spatial resolution is limited by the physics of diffraction, which acts as a low-pass filter. The information on sub-wavelength features is carried by evanescent waves, never reaching the camera,…

Optics · Physics 2018-12-13 Oren Solomon , Yonina C. Eldar , Maor Mutzafi , Mordechai Segev

Super-resolution Structured Illumination Microscopy (SR-SIM) enables fluorescence microscopy beyond the diffraction limit at high frame rates. Compared to other super-resolution microscopy techniques, the low photon fluence used in SR-SIM…

We exploit memory effect speckle correlations for the imaging of incoherent linear (single-photon) fluorescent sources behind scattering tissue. While memory effect-based imaging techniques have been heavily studied in the past, for thick…

Diffraction limit is manifested in the loss of high spatial frequency information that results from decay of evanescent waves. As a result, conventional far-field optics yields no information about an object's subwavelength features. Here…

Optics · Physics 2012-01-24 Leonid Alekseyev , Evgenii Narimanov , Jacob Khurgin

We show that the single emitter linewidth underlying a broadened ensemble emission spectrum can be extracted from correlations among the stochastic intensity fluctuations in the ensemble spectrum. Spectral correlations can be observed at…

Optics · Physics 2009-03-13 Xavier Brokmann , Lisa Marshall , Moungi Bawendi

The excited state population of single solid-state emitters is subjected to energy fluctuations around the equilibrium driven by the bath and relaxation through the emission of phonons or photons. Simultaneous measurement of the associated…

Quantum Physics · Physics 2021-05-12 Hendrik Utzat , Moungi G. Bawendi