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Neovascular age-related macular degeneration (nAMD) is a leading cause of vision loss among older adults, where disease activity detection and progression prediction are critical for nAMD management in terms of timely drug administration…

Image and Video Processing · Electrical Eng. & Systems 2025-01-27 Taha Emre , Teresa Araújo , Marzieh Oghbaie , Dmitrii Lachinov , Guilherme Aresta , Hrvoje Bogunović

Age-related macular degeneration (AMD) is a major cause of blindness in older adults, severely affecting vision and quality of life. Despite advances in understanding AMD, the molecular factors driving the severity of subretinal scarring…

Genomics · Quantitative Biology 2024-09-10 Kuan Yan , Yue Zeng , Dai Shi , Ting Zhang , Dmytro Matsypura , Mark C. Gillies , Ling Zhu , Junbin Gao

Robotic ultrasound (US) imaging has been seen as a promising solution to overcome the limitations of free-hand US examinations, i.e., inter-operator variability. However, the fact that robotic US systems cannot react to subject movements…

Robotics · Computer Science 2022-09-07 Zhongliang Jiang , Nehil Danis , Yuan Bi , Mingchuan Zhou , Markus Kroenke , Thomas Wendler , Nassir Navab

Forecasting motion of a specific target object is a common problem for surgical interventions, e.g. for localization of a target region, guidance for surgical interventions, or motion compensation. Optical coherence tomography (OCT) is an…

Image and Video Processing · Electrical Eng. & Systems 2020-06-02 Marcel Bengs , Nils Gessert , Alexander Schlaefer

Studies of the human brain during natural activities, such as locomotion, would benefit from the ability to image deep brain structures during these activities. While Positron Emission Tomography (PET) can image these structures, the bulk…

Robotics · Computer Science 2023-11-30 Junxiang Wang , Iulian I. Iordachita , Peter Kazanzides

Delayed dark adaptation due to impaired rod photoreceptor homeostasis has been reported as the earliest symptom of eye diseases such as age-related macular degeneration, diabetic retinopathy, and retinitis pigmentosa. Objective measurement…

Biological Physics · Physics 2021-12-16 Tae-Hoon Kim , Jie Ding , Xincheng Yao

Optical coherence tomography (OCT) is widely used for diagnosing and monitoring retinal diseases, such as age-related macular degeneration (AMD). The segmentation of biomarkers such as layers and lesions is essential for patient diagnosis…

Computer Vision and Pattern Recognition · Computer Science 2025-09-26 Botond Fazekas , Guilherme Aresta , Philipp Seeböck , Julia Mai , Ursula Schmidt-Erfurth , Hrvoje Bogunović

Respiratory motion limits the accuracy and precision of abdominal percutaneous procedures. In this paper, respiratory motion is compensated robotically using motion estimation models. Additionally, a teleoperated insertion is performed…

Systems and Control · Electrical Eng. & Systems 2025-11-27 Ana Cordon-Avila , Mostafa Selim , Momen Abayazid

Optical coherence tomography (OCT) imaging is a well-known technology for visualizing retinal layers and helps ophthalmologists to detect possible diseases. Accurate and early diagnosis of common retinal diseases can prevent the patients…

Image and Video Processing · Electrical Eng. & Systems 2022-03-04 Mohammad Rahimzadeh , Mahmoud Reza Mohammadi

Age-related macular degeneration (AMD) is the most common cause of blindness in developed countries, especially in people over 60 years of age. The workload of specialists and the healthcare system in this field has increased in recent…

Image and Video Processing · Electrical Eng. & Systems 2022-02-07 Saman Sotoudeh-Paima , Ata Jodeiri , Fedra Hajizadeh , Hamid Soltanian-Zadeh

Retinal imaging has emerged as a powerful, non-invasive modality for detecting and quantifying biomarkers of systemic diseases-ranging from diabetes and hypertension to Alzheimer's disease and cardiovascular disorders but current insights…

Image and Video Processing · Electrical Eng. & Systems 2025-05-28 Tariq M Khan , Toufique Ahmed Soomro , Imran Razzak

Optical Coherence Tomography(OCT) is a non-invasive technique capturing cross-sectional area of the retina in micro-meter resolutions. It has been widely used as a auxiliary imaging reference to detect eye-related pathology and predict…

Image and Video Processing · Electrical Eng. & Systems 2022-09-01 Shuo Chen , Da Ma , Sieun Lee , Timothy T. L. Yu , Gavin Xu , Donghuan Lu , Karteek Popuri , Myeong Jin Ju , Marinko V. Sarunic , Mirza Faisal Beg

Important challenges in retinal microsurgery include prolonged operating time, inadequate force feedback, and poor depth perception due to a constrained top-down view of the surgery. The introduction of robot-assisted technology could…

Robotics · Computer Science 2023-12-08 Peiyao Zhang , Ji Woong Kim , Peter Gehlbach , Iulian Iordachita , Marin Kobilarov

Eye diseases are common in older Americans and can lead to decreased vision and blindness. Recent advancements in imaging technologies allow clinicians to capture high-quality images of the retinal blood vessels via Optical Coherence…

Computer Vision and Pattern Recognition · Computer Science 2024-07-23 Jacob Thrasher , Annahita Amireskandari , Prashnna Gyawali

This paper proposes an automated method for the segmentation and extraction of the posterior segment of the human eye, including the vitreous, retina, choroid, and sclera compartments, using multi-vendor optical coherence tomography (OCT)…

Image and Video Processing · Electrical Eng. & Systems 2021-10-19 Bilal Hassan , Taimur Hassan , Ramsha Ahmed , Shiyin Qin , Naoufel Werghi

Optical coherence tomography (OCT) helps ophthalmologists assess macular edema, accumulation of fluids, and lesions at microscopic resolution. Quantification of retinal fluids is necessary for OCT-guided treatment management, which relies…

Image and Video Processing · Electrical Eng. & Systems 2022-12-15 Reza Rasti , Armin Biglari , Mohammad Rezapourian , Ziyun Yang , Sina Farsiu

Optical coherence tomography (OCT) is a non-invasive imaging technique with extensive clinical applications in ophthalmology. OCT enables the visualization of the retinal layers, playing a vital role in the early detection and monitoring of…

At the present time Optical Coherence Tomography (OCT) is among the most commonly used non-invasive imaging methods for the acquisition of large volumetric scans of human retinal tissues and vasculature. To resolve decisive information from…

Computer Vision and Pattern Recognition · Computer Science 2021-11-02 D. Sitenko , B. Boll , C. Schnörr

Dynamic scattering remains a significant challenge to the practical deployment of anti-scattering imaging. Existing methods, such as transmission matrix measurements, iterative wavefront shaping, and optical phase conjugation, depend on a…

Alterations in retinal layer thickness, measurable using Optical Coherence Tomography (OCT), have been associated with neurodegenerative diseases such as Alzheimer's disease (AD). While previous studies have mainly focused on segmented…

Computer Vision and Pattern Recognition · Computer Science 2025-11-10 Yasemin Turkan , F. Boray Tek , M. Serdar Nazlı , Öykü Eren