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Purpose: VT is a life-threatening arrhythmia commonly treated with catheter ablation; however, some cases remain refractory to conventional treatment. STAR has emerged as a non-invasive option for such patients. While photon-based STAR has…

This study evaluates dynamic conformal arc (DCA) therapy as an alternative to volumetric modulated arc therapy (VMAT) for stereotactic body radiation therapy (SBRT) of lung cancer. The rationale for DCA is lower geometric complexity and…

Medical Physics · Physics 2019-05-07 Rasmus Bokrantz , Minna Wedenberg , Peter Sandwall

Advanced radiotherapy approaches such as FLASH irradiation and spatially fractionated radiotherapy (SFRT) show potential to improve the therapeutic ratio, yet their biological mechanisms and optimal delivery parameters remain uncertain.…

Proton radiography combined with X-ray computed tomography (CT) has been proposed to obtain a patient-specific calibration curve and reduce range uncertainties in cancer treatment with charged particles. The main aim of this study was to…

Non-coplanar Intensity-Modulated Radiation Therapy (IMRT) goes a step further by orienting the gantry carrying the radiation beam and the patient couch in a non-coplanar manner to accurately target the cancer region and better avoid…

Medical Physics · Physics 2023-05-16 Fang Guo , Franklin Okoli , Ulrike Schick , Dimitris Visvikis , Antoine Valeri , Julien Bert

A new delivery option for cancer centers equipped with linear accelerators fitted with multi-leaf collimators (MLC) -- i.e. centers which can perform intensity modulated radiation therapy (IMRT) -- is rotational delivery. In rotational…

Medical Physics · Physics 2009-10-27 David Craft , Thomas Bortfeld

This paper describes the algorithm and examines the performance of an IMRT beam-angle optimization (BAO) system. In this algorithm successive sets of beam angles are selected from a set of predefined directions using a fast simulated…

Medical Physics · Physics 2009-11-10 David Djajaputra , Qiuwen Wu , Yan Wu , Radhe Mohan

Proton therapy provides superior dose conformity compared with photon radiotherapy, concentrating radiation within the tumor while sparing adjacent healthy tissue. This advantage has been most effectively realized for static tumors in…

Medical Physics · Physics 2025-10-09 Vivek Maradia , Nick Yue , Adam Molzahn , Jingqian Wang , Mark Pankuch , Serdar Charyyev , Billy W. Loo

We present Integrated Multimodal Perception (IMP), a simple and scalable multimodal multi-task training and modeling approach. IMP integrates multimodal inputs including image, video, text, and audio into a single Transformer encoder with…

Computer Vision and Pattern Recognition · Computer Science 2023-12-12 Hassan Akbari , Dan Kondratyuk , Yin Cui , Rachel Hornung , Huisheng Wang , Hartwig Adam

In this paper, we proposed a method to optimize adaptive proton FLASH therapy (ADP FLASH) using modularized pin ridge filters (pRFs) by recycling module pins from the initial plan while reducing pRF adjustments in adaptive FLASH planning.…

Medical Physics · Physics 2025-02-04 Ahmal Jawad Zafar , Xiaofeng Yang , Zachary Diamond , Tian Sibo , David Yu , Pretesh R. Patel , Jun Zhou

BACKGROUND AND OBJECTIVE: The research done in the field of Augmented Reality (AR) for patient positioning in radiation therapy is scarce. We propose an efficient and cost-effective algorithm for tracking the scene and the patient to…

Computer Vision and Pattern Recognition · Computer Science 2021-08-02 Hamid Sarmadi , Rafael Muñoz-Salinas , M. Álvaro Berbís , Antonio Luna , R. Medina-Carnicer

Computed Tomography (CT) with its remarkable capability for three-dimensional imaging from multiple projections, enjoys a broad range of applications in clinical diagnosis, scientific observation, and industrial detection. Neural Adaptive…

Image and Video Processing · Electrical Eng. & Systems 2023-11-06 Bo Xiong , Changqing Su , Zihan Lin , You Zhou , Zhaofei Yu

Exudative (wet) age-related macular degeneration (AMD) is a leading cause of vision loss in older adults, typically treated with intravitreal injections. Emerging therapies, such as subretinal injections of stem cells, gene therapy, small…

Ion beam therapy has become a frequently applied form of cancer therapy over the last years. The advantage of ion beam therapy over conventional radiotherapy using photons is the strongly localized dose deposition, leading to a reduction of…

Instrumentation and Detectors · Physics 2020-07-28 F. Ulrich-Pur , T. Bergauer , A. Burker , S. Hatamikia , A. Hirtl , C. Irmler , S. Kaser , P. Paulitsch , F. Pitters , V. Teufelhart

Traditionally, optimization of radiation therapy (RT) treatment plans has been done before the initiation of RT course, using population-wide estimates for patients' response to therapy. However, recent technological advancements have…

Medical Physics · Physics 2021-02-15 Stefan C. M. ten Eikelder , Ali Ajdari , Thomas Bortfeld , Dick den Hertog

Model-Based Image Reconstruction (MBIR) methods significantly enhance the quality of computed tomographic (CT) reconstructions relative to analytical techniques, but are limited by high computational cost. In this paper, we propose a…

Image and Video Processing · Electrical Eng. & Systems 2019-11-22 Venkatesh Sridhar , Xiao Wang , Gregery T. Buzzard , Charles A. Bouman

The dose delivered to the planning target volume by proton beams is highly conformal, sparing organs at risk and normal tissues. New treatment planning systems adapted to spot scanning techniques have been recently proposed to…

Medical Physics · Physics 2022-05-18 François Smekens , Nicolas Freud , Bruno Sixou , Guillaume Beslon , Jean M Létang

We present a nitrogen-targeting-Proton-Carbon-Alpha-Therapy method, abbreviated as Proton-CAT, which partially converts protons into carbon-12 and $\alpha$ particles through nuclear reactions between protons and nitrogen-15. Monte Carlo…

Radiation therapy is an important tool in the treatment of breast cancer and can play a crucial role in improving patient outcomes. For breast cancer, if the technique has been for a long time the use of 3DCRT, clinicians have seen the…

Online adaptive radiation therapy (ART) has great promise to significantly reduce normal tissue toxicity and/or improve tumor control through real-time treatment adaptations based on the current patient anatomy. However, the major technical…

Medical Physics · Physics 2015-05-18 Chunhua Men , Xun Jia , Steve. B. Jiang
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