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For 3D spatial transcriptomics (ST), the high per-section acquisition cost of fully sampling every tissue section remains a significant challenge. Although recent approaches predict gene expression from histology images, these methods…

Image and Video Processing · Electrical Eng. & Systems 2025-07-30 Jiahe Qian , Yaoyu Fang , Xinkun Wang , Lee A. Cooper , Bo Zhou

Deep learning-based medical image segmentation typically requires large amount of labeled data for training, making it less applicable in clinical settings due to high annotation cost. Semi-supervised learning (SSL) has emerged as an…

Image and Video Processing · Electrical Eng. & Systems 2025-03-03 Yichi Zhang , Bohao Lv , Le Xue , Wenbo Zhang , Yuchen Liu , Yu Fu , Yuan Cheng , Yuan Qi

Foundation models (FMs) have shown great promise in medical imaging, but most FMs are trained on unimodal data within isolated domains, such as brain MRI alone. Human aging and disease arise through coordinated biological processes across…

Computer Vision and Pattern Recognition · Computer Science 2026-05-11 Qiangqiang Wu , Grace McIlvain , Zhou Yu , Junhao Wen

Spatially resolved transcriptomics represents a significant advancement in single-cell analysis by offering both gene expression data and their corresponding physical locations. However, this high degree of spatial resolution entails a…

Genomics · Quantitative Biology 2024-03-19 Xiaoyu Li , Wenwen Min , Shunfang Wang , Changmiao Wang , Taosheng Xu

Spatio-temporal reasoning is essential in understanding real-world environments in various fields, eg, autonomous driving and sports analytics. Recent advances have improved the spatial reasoning ability of Vision-Language Models (VLMs) by…

Computer Vision and Pattern Recognition · Computer Science 2025-03-27 Dohwan Ko , Sihyeon Kim , Yumin Suh , Vijay Kumar B. G , Minseo Yoon , Manmohan Chandraker , Hyunwoo J. Kim

Spatial transcriptomics (ST) technologies enable transcriptome-wide gene expression profiling while preserving spatial resolution, offering unprecedented opportunities to uncover complex spatial structures. Due to the ultra-high…

Applications · Statistics 2026-03-11 Changhu Wang , Qiyun Huang , Zihao Chen , Jin Liu , Ruibin Xi

Foundation models (FMs) have emerged as a transformative paradigm in medical image analysis, offering the potential to provide generalizable, task-agnostic solutions across a wide range of clinical tasks and imaging modalities. Their…

Computer Vision and Pattern Recognition · Computer Science 2025-11-04 Karma Phuntsho , Abdullah , Kyungmi Lee , Ickjai Lee , Euijoon Ahn

Traffic forecasting represents a crucial problem within intelligent transportation systems. In recent research, Large Language Models (LLMs) have emerged as a promising method, but their intrinsic design, tailored primarily for sequential…

Machine Learning · Computer Science 2025-09-18 Hyotaek Jeon , Hyunwook Lee , Juwon Kim , Sungahn Ko

We propose a method of aligning a source image to a target image, where the transform is specified by a dense vector field. The two images are encoded as feature hierarchies by siamese convolutional nets. Then a hierarchy of aligner modules…

Computer Vision and Pattern Recognition · Computer Science 2019-04-05 Eric Mitchell , Stefan Keselj , Sergiy Popovych , Davit Buniatyan , H. Sebastian Seung

Spatio-Temporal predictive Learning is a self-supervised learning paradigm that enables models to identify spatial and temporal patterns by predicting future frames based on past frames. Traditional methods, which use recurrent neural…

Computer Vision and Pattern Recognition · Computer Science 2024-11-18 Andrea Alfarano , Alberto Alfarano , Linda Friso , Andrea Bacciu , Irene Amerini , Fabrizio Silvestri

Medical image segmentation is routinely performed to isolate regions of interest, such as organs and lesions. Currently, deep learning is the state of the art for automatic segmentation, but is usually limited by the need for supervised…

Image and Video Processing · Electrical Eng. & Systems 2021-02-05 Umaseh Sivanesan , Luis H. Braga , Ranil R. Sonnadara , Kiret Dhindsa

We introduce StrCGAN (Stellar Cyclic GAN), a generative model designed to enhance low-resolution astrophotography images. Our goal is to reconstruct high fidelity ground truth like representations of stellar objects, a task that is…

Computer Vision and Pattern Recognition · Computer Science 2025-11-26 Shantanusinh Parmar , Silas Janke

Single-cell-resolution spatial transcriptomics profiles gene expression at cellular locations in native tissues, yet accurate cell-type annotation remains challenging: imaging-based platforms are constrained by targeted gene panels, whereas…

Cell Behavior · Quantitative Biology 2026-05-27 Yiyang Zhang , Bokai Zhao , Xiaoru Zhang , Zongchang Du , Xiaojuan Sun , Tianzi Jiang

Automated segmentation is a fundamental medical image analysis task, which enjoys significant advances due to the advent of deep learning. While foundation models have been useful in natural language processing and some vision tasks for…

Computer Vision and Pattern Recognition · Computer Science 2025-05-12 Hanxue Gu , Haoyu Dong , Jichen Yang , Maciej A. Mazurowski

Accurate medical image segmentation is essential for clinical diagnosis and treatment planning. While recent interactive foundation models (e.g., nnInteractive) enhance generalization through large-scale multimodal pretraining, they still…

Computer Vision and Pattern Recognition · Computer Science 2025-12-23 Ziyu Zhang , Yi Yu , Simeng Zhu , Ahmed Aly , Yunhe Gao , Ning Gu , Yuan Xue

Due to the limited availability of data, existing few-shot learning methods trained from scratch fail to achieve satisfactory performance. In contrast, large-scale pre-trained models such as CLIP demonstrate remarkable few-shot and…

Computer Vision and Pattern Recognition · Computer Science 2023-11-20 Kun Song , Huimin Ma , Bochao Zou , Huishuai Zhang , Weiran Huang

Single-cell spatial transcriptomics (ST) offers a unique approach to measuring gene expression profiles and spatial cell locations simultaneously. However, most existing ST methods assume that cells in closer spatial proximity exhibit more…

Genomics · Quantitative Biology 2025-06-10 Xiongtao Xiao , Xiaofeng Chen , Feiyan Jiang , Songming Zhang , Wenming Cao , Cheng Tan , Zhangyang Gao , Zhongshan Li

The spatial correlations and the temporal contexts are indispensable in Electroencephalogram (EEG)-based emotion recognition. However, the learning of complex spatial correlations among several channels is a challenging problem. Besides,…

Signal Processing · Electrical Eng. & Systems 2022-11-23 Yiheng Tang , Yongxiong Wang , Xiaoli Zhang , Zhe Wang

Most prior unsupervised domain adaptation approaches for medical image segmentation are narrowly tailored to either the source-accessible setting, where adaptation is guided by source-target alignment, or the source-free setting, which…

Computer Vision and Pattern Recognition · Computer Science 2026-03-10 Xin Wang , Yin Guo , Jiamin Xia , Kaiyu Zhang , Niranjan Balu , Mahmud Mossa-Basha , Linda Shapiro , Chun Yuan

Multi-modal medical image segmentation plays an essential role in clinical diagnosis. It remains challenging as the input modalities are often not well-aligned spatially. Existing learning-based methods mainly consider sharing trainable…

Computer Vision and Pattern Recognition · Computer Science 2021-01-06 Jingkun Chen , Wenqi Li , Hongwei Li , Jianguo Zhang