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Cell signaling, gene expression, and metabolism are affected by cell-cell heterogeneity and random changes in the environment. The effects of such fluctuations on cell signaling and gene expression have recently been studied intensively…

Biological Physics · Physics 2015-04-02 A. -K. Gustavsson , C. B. Adiels , B. Mehlig , M. Goksör

As cells grow and divide under a given environment, they become crowded and resources are limited, as seen in bacterial biofilms and multicellular aggregates. These cells often show strong interactions through exchanging chemicals, as in…

Cell Behavior · Quantitative Biology 2017-02-08 Jumpei F Yamagishi , Nen Saito , Kunihiko Kaneko

A consumer Behaviour model is considered in the context of a network of interacting individuals in an energy market. We propose and analyse a simple dynamical model of an ensemble of coupled active elements mimicking consumers' Behaviour,…

Adaptation and Self-Organizing Systems · Physics 2014-01-29 Nick. J. McCullen , Mikhail. V. Ivanchenko , Vladimir. D. Shalfeev , William. F. Gale

In this work we prove occurrence of a super-critical Hopf bifurcation in a model of white blood cell formation structured by three maturation stages. We provide an explicit analytical expression for the bifurcation point depending on model…

Dynamical Systems · Mathematics 2019-10-24 Franziska Knauer , Thomas Stiehl , Anna Marciniak-Czochra

During development, spatio-temporal patterns ranging from checkerboard to engulfing occur with precise proportions of the respective cell fates. Key developmental regulators are intracellular transcriptional interactions and intercellular…

Biological Physics · Physics 2022-11-15 Simon Schardt , Sabine C. Fischer

A cross-diffusion system modeling the information herding of individuals is analyzed in a bounded domain with no-flux boundary conditions. The variables are the species' density and an influence function which modifies the information state…

Analysis of PDEs · Mathematics 2018-12-24 Ansgar Jüngel , Christian Kuehn , Lara Trussardi

During development, highly ordered structures emerge as cells collectively coordinate with each other. While recent advances have clarified how individual cells process and respond to external signals, understanding collective cellular…

Biological Physics · Physics 2026-02-05 Ashutosh Tripathi , Jörn Dunkel , Dominic J. Skinner

Bifurcation analysis collects techniques for characterizing the dependence of certain classes of solutions of a dynamical system on variations in problem parameters. Common solution classes of interest include equilibria and periodic…

Dynamical Systems · Mathematics 2025-11-05 Harry Dankowicz , Jan Sieber

Clustering bifurcations are investigated by considering models of globally coupled map lattices. Typical classes of clustering bifurcations are revealed. The clustering bifurcation thresholds of the coupled system are closely related to the…

chao-dyn · Physics 2009-10-30 Fagen Xie , Gang Hu

A number of physical processes show some form of bifurcation or periodic splintering of a single distribution into two new ones. Recently, it has been noted that cavity searches for interactions between photons and exotic fields may also…

Instrumentation and Methods for Astrophysics · Physics 2013-07-09 C. Scarlett

This paper presents an investigation of the dynamics of two coupled non-identical FitzHugh-Nagumo neurons with delayed synaptic connection. We consider coupling strength and time delay as bifurcation parameters, and try to classify all…

Dynamical Systems · Mathematics 2015-10-07 Niloofar Farajzadeh Tehrani , MohammadReza Razvan

We investigate the emergence of complex dynamics in a system of coupled dissipative kicked rotors and show that critical transitions can be understood via bifurcations of simple states. We study multistability and bifurcations in the single…

Chaotic Dynamics · Physics 2025-10-27 Jin Yan

Cellular signaling is essential in information processing and decision making. Therefore, a variety of experimental approaches have been developed to study signaling on bulk and single-cell level. Single-cell measurements of signaling…

Quantitative Methods · Quantitative Biology 2019-04-18 Carolin Loos , Jan Hasenauer

Motivated by experimental and theoretical work on autonomous oscillations in yeast, we analyze ordinary differential equations models of large populations of cells with cell-cycle dependent feedback. We assume a particular type of feedback…

Dynamical Systems · Mathematics 2011-12-02 Todd Young , Bastien Fernandez , Richard Buckalew , Gregory Moses , Erik Boczko

The cell cycle is a tightly controlled process, yet its underlying genetic network shows marked differences across species. Which of the associated structural features follow solely from the ability to impose the appropriate gene expression…

Molecular Networks · Quantitative Biology 2015-06-12 M. Zagorski , A. Krzywicki , O. C. Martin

Basic problems for the construction of a scenario for the Life are discussed. To study the problems in terms of dynamical systems theory, a scheme of intra-inter dynamics is presented. It consists of internal dynamics of a unit, interaction…

adap-org · Physics 2015-06-24 Kunihiko Kaneko

Biofilament-motor protein complexes are ubiquitous in biology and drive the transport of cargo vital for many fundamental cellular processes. As they move, motor proteins exert compressive forces on the filaments to which they are attached,…

Biological Physics · Physics 2024-06-12 Bethany Clarke , Yongyun Hwang , Eric Keaveny

Cancer stem cells have been shown to be critical to the development of a variety of solid cancers. The precise interplay mechanisms between cancer stem cells and the rest of a tissue are still not elucidated. To shed light on the…

Cell Behavior · Quantitative Biology 2019-09-04 L. Benítez , L. Barberis , C. A. Condat

Quantifying the outcomes of cells collisions is a crucial step in building the foundations of a kinetic theory of living matter. Here, we develop a mechanical theory of such collisions by first representing individual cells as extended…

Biological Physics · Physics 2019-12-11 Pierre Recho , Thibaut Putelat , Lev Truskinovsky

Gene regulatory networks, i.e. DNA segments in a cell which interact with each other indirectly through their RNA and protein products, lie at the heart of many important intracellular signal transduction processes. In this paper we analyse…

Analysis of PDEs · Mathematics 2014-04-03 Mark Chaplain , Mariya Ptashnyk , Marc Sturrock
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