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Most recently, the pathology diagnosis of cancer is shifting to integrating molecular makers with histology features. It is a urgent need for digital pathology methods to effectively integrate molecular markers with histology, which could…

Image and Video Processing · Electrical Eng. & Systems 2023-06-28 Xiaofei Wang , Stephen Price , Chao Li

This paper shows the machine learning system which performs instance segmentation of cytological images in veterinary medicine. Eleven cell types were used directly and indirectly in the experiments, including damaged and unrecognized…

The goal of Machine Learning to automatically learn from data, extract knowledge and to make decisions without any human intervention. Such automatic (aML) approaches show impressive success. Recent results even demonstrate intriguingly…

Artificial Intelligence · Computer Science 2021-03-16 Andreas Holzinger , Markus Plass , Katharina Holzinger , Gloria Cerasela Crisan , Camelia-M. Pintea , Vasile Palade

In this paper, we introduce a novel and interpretable methodology to cluster subjects suffering from cancer, based on features extracted from their biopsies. Contrary to existing approaches, we propose here to capture complex patterns in…

Quantitative Methods · Quantitative Biology 2020-07-07 Yassine El Ouahidi , Matis Feller , Matthieu Talagas , Bastien Pasdeloup

In routine colorectal cancer management, histologic samples stained with hematoxylin and eosin are commonly used. Nonetheless, their potential for defining objective biomarkers for patient stratification and treatment selection is still…

Quantitative Methods · Quantitative Biology 2024-09-26 Fabi Prezja , Leevi Annala , Sampsa Kiiskinen , Suvi Lahtinen , Timo Ojala , Pekka Ruusuvuori , Teijo Kuopio

Generative approaches to clustering provide information on geometric properties of clusters, whereas discriminative approaches provide boundaries between clusters. Ideas from both approaches are incorporated to present a fully unsupervised,…

Machine Learning · Statistics 2026-04-28 Mackenzie R. Neal , Paul D. McNicholas , Arthur White

The objectives of this paper are to explore ways to analyze breast cancer dataset in the context of unsupervised learning without prior training model. The paper investigates different ways of clustering techniques as well as preprocessing.…

Machine Learning · Computer Science 2021-09-06 Somenath Chakraborty , Beddhu Murali

Breast cancer has the highest mortality among cancers in women. Computer-aided pathology to analyze microscopic histopathology images for diagnosis with an increasing number of breast cancer patients can bring the cost and delays of…

Computer Vision and Pattern Recognition · Computer Science 2020-03-03 Abhijeet Patil , Dipesh Tamboli , Swati Meena , Deepak Anand , Amit Sethi

Non-small cell lung cancer (NSCLC) remains a major global health challenge, with high post-surgical recurrence rates underscoring the need for accurate pathological response predictions to guide personalized treatments. Although artificial…

We present a reproducible deep learning pipeline for leukemic cell classification, focusing on system architecture, experimental robustness, and software design choices for medical image analysis. Acute lymphoblastic leukemia (ALL) is the…

Computer Vision and Pattern Recognition · Computer Science 2026-01-06 Douglas Costa Braga , Daniel Oliveira Dantas

Machine Learning (ML) models offer significant potential for advancing cell counting applications in neuroscience, medical research, pharmaceutical development, and environmental monitoring. However, implementing these models effectively…

Hepatocellular carcinoma is the most spread primary liver cancer across the world ($\sim$80\% of the liver tumors). The gold standard for HCC diagnosis is liver biopsy. However, in the clinical routine, expert radiologists provide a visual…

Computer Vision and Pattern Recognition · Computer Science 2025-01-15 E. Sarfati , A. Bône , M-M. Rohé , C. Aubé , M. Ronot , P. Gori , I. Bloch

We apply deep learning (DL) on Magnetic resonance spectroscopy (MRS) data for the task of brain tumor detection. Medical applications often suffer from data scarcity and corruption by noise. Both of these problems are prominent in our data…

Machine Learning · Computer Science 2021-12-17 Diyuan Lu , Gerhard Kurz , Nenad Polomac , Iskra Gacheva , Elke Hattingen , Jochen Triesch

The assessment of protein expression in immunohistochemistry (IHC) images provides important diagnostic, prognostic and predictive information for guiding cancer diagnosis and therapy. Manual scoring of IHC images represents a logistical…

Computer Vision and Pattern Recognition · Computer Science 2016-06-27 Humayun Irshad , Eun-Yeong Oh , Daniel Schmolze , Liza M Quintana , Laura Collins , Rulla M. Tamimi , Andrew H. Beck

We present a machine learning (ML) pipeline to identify star clusters in the multi{color images of nearby galaxies, from observations obtained with the Hubble Space Telescope as part of the Treasury Project LEGUS (Legacy ExtraGalactic…

Astrophysics of Galaxies · Physics 2021-02-10 Gustavo Perez , Matteo Messa , Daniela Calzetti , Subhransu Maji , Dooseok Jung , Angela Adamo , Mattia Siressi

The aim of the systematic review was to assess recently published studies on diagnostic test accuracy of glioblastoma treatment response monitoring biomarkers in adults, developed through machine learning (ML). Articles were searched for…

Melanoma is a type of skin cancer developed from melanocytes. It is one of the most lethal types of cancer, accounting for approximately 75% of skin cancer deaths. Late stage melanoma is very difficult to treat, since the cancer cells are…

Quantitative Methods · Quantitative Biology 2018-11-28 Xue Teng , Fuad Gwadry , Haley McConkey , Scott Ernst , Femida Gwadry-Sridhar

We present cytometric classification of live healthy and cancer cells by using the spatial morphological and textural information found in the label-free quantitative phase images of the cells. We compare both healthy cells to primary tumor…

Quantitative Methods · Quantitative Biology 2020-01-23 Darina Roitshtain , Lauren Wolbromsky , Evgeny Bal , Hayit Greenspan , Lisa L. Satterwhite , Natan T. Shaked

Flow cytometry mainly used for detecting the characteristics of a number of biochemical substances based on the expression of specific markers in cells. It is particularly useful for detecting membrane surface receptors, antigens, ions, or…

Machine Learning · Computer Science 2023-03-17 Yanhua Xu

Epigenetic alterations have an important role in the development of several types of cancer. Epigenetic studies generate a large amount of data, which makes it essential to develop novel models capable of dealing with large-scale data. In…

Machine Learning · Computer Science 2021-02-22 del Amor Rocío , Colomer Adrián , Monteagudo Carlos , Naranjo Valery
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