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Surgery for gliomas (intrinsic brain tumors), especially when low-grade, is challenging due to the infiltrative nature of the lesion. Currently, no real-time, intra-operative, label-free and wide-field tool is available to assist and guide…

Stroke is the second most common cause of death in developed countries, where rapid clinical intervention can have a major impact on a patient's life. To perform the revascularization procedure, the decision making of physicians considers…

Computer Vision and Pattern Recognition · Computer Science 2018-09-25 Adriano Pinto , Sergio Pereira , Raphael Meier , Victor Alves , Roland Wiest , Carlos A. Silva , Mauricio Reyes

Geometric high-fidelity mesh reconstruction from LiDAR-inertial scans remains challenging in large, complex indoor environments -- such as cultural buildings -- where point cloud sparsity, geometric drift, and fixed fusion parameters…

Computer Vision and Pattern Recognition · Computer Science 2026-04-13 Muhammad Affan , Ville Lehtola , George Vosselman

Recently, deep neural networks have greatly advanced histopathology image segmentation but usually require abundant annotated data. However, due to the gigapixel scale of whole slide images and pathologists' heavy daily workload, obtaining…

Computer Vision and Pattern Recognition · Computer Science 2023-03-13 Wentao Pan , Jiangpeng Yan , Hanbo Chen , Jiawei Yang , Zhe Xu , Xiu Li , Jianhua Yao

The coagulation of blood after it is drawn from the body poses a significant challenge for hematological analysis, potentially leading to inaccurate test results and altered cellular characteristics, compromising diagnostic reliability.…

Post-endoscopic gastrointestinal (GI) rebleeding frequently occurs within the first 72 hours after therapeutic hemostasis and remains a major cause of early morbidity and mortality. Existing non-invasive monitoring approaches primarily…

Image and Video Processing · Electrical Eng. & Systems 2026-01-27 Yunhao Bian , Dawei Wang , Mingyang Shen , Xinze Li , Jiayi Shi , Ziyao Zhou , Tiancheng Cao , Hen-Wei Huang

Label-free imaging has gained broad interest because of its potential to omit elaborate staining procedures which is especially relevant for in vivo use. Label-free multiphoton microscopy (MPM), for instance, exploits two-photon excitation…

The characterization of white blood cells (WBCs) is crucial for blood analyses and disease diagnoses. However, current standard techniques rely on cell labeling, a process which imposes significant limitations. Here we present…

Biological Physics · Physics 2015-05-12 Jonghee Yoon , Kyoohyun Kim , HyunJoo Park , Chulhee Choi , Seongsoo Jang , YongKeun Park

Existing multimodal document question answering methods predominantly adopt a Pre-Ingestion (PI) strategy: during the indexing phase, a Vision Language Model (VLM) is called on every page to generate page descriptions that are then encoded…

Computation and Language · Computer Science 2026-02-27 Tao Xu

Arterial spin labeling (ASL) allows to quantify the cerebral blood flow (CBF) by magnetic labeling of the arterial blood water. ASL is increasingly used in clinical studies due to its noninvasiveness, repeatability and benefits in…

Computer Vision and Pattern Recognition · Computer Science 2018-06-13 Cagdas Ulas , Giles Tetteh , Stephan Kaczmarz , Christine Preibisch , Bjoern H. Menze

Three-dimensional (3D) imaging of the subcellular organisation and morphology of cells and tissues is essential for understanding biological function. Although staining is the most widely used approach for visualising biological samples…

Deep learning has shown significant potential in diagnosing neurodegenerative diseases from MRI data. However, most existing methods rely heavily on large volumes of labeled data and often yield representations that lack interpretability.…

Computer Vision and Pattern Recognition · Computer Science 2025-09-10 Fangqi Cheng , Yingying Zhao , Xiaochen Yang

Time-resolved spectral techniques play an important analysis tool in many contexts, from physical chemistry to biomedicine. Customarily, the label-free detection of analytes is manually performed by experts through the aid of classic…

Machine Learning · Computer Science 2020-11-17 Stefano Rini , Hirotsugu Hiramatsu

The multi-scale information among the whole slide images (WSIs) is essential for cancer diagnosis. Although the existing multi-scale vision Transformer has shown its effectiveness for learning multi-scale image representation, it still…

Computer Vision and Pattern Recognition · Computer Science 2023-05-26 Saisai Ding , Juncheng Li , Jun Wang , Shihui Ying , Jun Shi

Intraoperative assessment of tissue can be guided through fluorescence imaging which involves systemic dosing with a fluorophore and subsequent examination of the tissue region of interest with a near-infrared camera. This typically…

Image and Video Processing · Electrical Eng. & Systems 2022-11-11 Jonathan P. Epperlein , Niall P. Hardy , Pol Mac Aonghusa , Ronan A. Cahill

Designing a robotic system that functions effectively within the specific environment of a Magnetic Resonance Imaging (MRI) scanner requires solving numerous technical issues, such as maintaining the robot's precision and stability under…

Robotics · Computer Science 2026-01-06 Wenhui Chu , Aobo Jin , Hardik A. Gohel

General-purpose Large Vision-Language Models (LVLMs), despite their massive scale, often falter in dermatology due to "diffuse attention" - the inability to disentangle subtle pathological lesions from background noise. In this paper, we…

Computer Vision and Pattern Recognition · Computer Science 2026-01-15 Lijun Liu , Linwei Chen , Zhishou Zhang , Meng Tian , Hengfu Cui , Ruiyang Li , Zhaocheng Liu , Qiang Ju , Qianxi Li , Hong-Yu Zhou

In-context learning (ICL) with Large Vision Models (LVMs) presents a promising avenue in medical image segmentation by reducing the reliance on extensive labeling. However, the ICL performance of LVMs highly depends on the choices of visual…

Computer Vision and Pattern Recognition · Computer Science 2024-07-17 Chenwei Wu , David Restrepo , Zitao Shuai , Zhongming Liu , Liyue Shen

We propose a fluid-based registration framework of medical images based on implicit neural representation. By integrating implicit neural representation and Large Deformable Diffeomorphic Metric Mapping (LDDMM), we employ a Multilayer…

Image and Video Processing · Electrical Eng. & Systems 2023-11-28 Chulong Zhang , Xiaokun Liang

Dynamic positron emission tomography (PET) and kinetic modeling are pivotal in advancing tracer development research in small animal studies. Accurate kinetic modeling requires precise input function estimation, traditionally achieved via…

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