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The breadth, scale, and temporal granularity of modern electronic health records (EHR) systems offers great potential for estimating personalized and contextual patient health trajectories using sequential deep learning. However, learning…

Electronic Health Record (EHR) has become an essential tool in the healthcare ecosystem, providing authorized clinicians with patients' health-related information for better treatment. While most developed countries are taking advantage of…

We present Federated Timeline Synthesis (FTS), a novel framework for training generative foundation models across distributed timeseries data applied to electronic health records (EHR). At its core, FTS represents patient history as…

Machine Learning · Computer Science 2025-07-01 Pawel Renc , Michal K. Grzeszczyk , Linglong Qian , Nassim Oufattole , Jeff Rasley , Arkadiusz Sitek

Motivation: Electronic health record (EHR) data provides a new venue to elucidate disease comorbidities and latent phenotypes for precision medicine. To fully exploit its potential, a realistic data generative process of the EHR data needs…

Machine Learning · Computer Science 2021-05-05 Ziyang Song , Xavier Sumba Toral , Yixin Xu , Aihua Liu , Liming Guo , Guido Powell , Aman Verma , David Buckeridge , Ariane Marelli , Yue Li

Electronic health records (EHR) are widely believed to hold a profusion of actionable insights, encrypted in an irregular, semi-structured format, amidst a loud noise background. To simplify learning patterns of health and disease, medical…

Computation and Language · Computer Science 2022-12-13 David A. Bloore , Romane Gauriau , Anna L. Decker , Jacob Oppenheim

The extraction of relevant data from Electronic Health Records (EHRs) is crucial to identifying symptoms and automating epidemiological surveillance processes. By harnessing the vast amount of unstructured text in EHRs, we can detect…

Computation and Language · Computer Science 2025-02-10 Juliano Genari , Guilherme Tegoni Goedert

Access to high-quality medical data is often restricted due to privacy concerns, posing significant challenges for training artificial intelligence (AI) algorithms within Electronic Health Record (EHR) applications. In this study, prompt…

Artificial Intelligence · Computer Science 2025-04-30 Polycarp Nalela

Synthetic data generation offers a promising solution to enhance the usefulness of Electronic Healthcare Records (EHR) by generating realistic de-identified data. However, the existing literature primarily focuses on the quality of…

Machine Learning · Computer Science 2024-04-29 Resmi Ramachandranpillai , Md Fahim Sikder , David Bergström , Fredrik Heintz

The widespread adoption of electronic health records and digital healthcare data has created a demand for data-driven insights to enhance patient outcomes, diagnostics, and treatments. However, using real patient data presents privacy and…

Machine Learning · Computer Science 2023-11-15 Aryan Jadon , Shashank Kumar

The presence of detailed clinical information in electronic health record (EHR) systems presents promising prospects for enhancing patient care through automated retrieval techniques. Nevertheless, it is widely acknowledged that accessing…

Information Retrieval · Computer Science 2024-09-13 Abderrahim Oussama Batouche , Eugen Czeizler , Miika Koskinen , Tuomas Mirtti , Antti Sakari Rannikko

We propose RareGraph-Synth, a knowledge-guided, continuous-time diffusion framework that generates realistic yet privacy-preserving synthetic electronic-health-record (EHR) trajectories for ultra-rare diseases. RareGraph-Synth unifies five…

Machine Learning · Computer Science 2025-10-09 Khartik Uppalapati , Shakeel Abdulkareem , Bora Yimenicioglu

Access to individual-level health data is essential for gaining new insights and advancing science. In particular, modern methods based on artificial intelligence rely on the availability of and access to large datasets. In the health…

Irregular sampling of time series in electronic health records (EHRs) is one of the main challenges for developing machine learning models. Additionally, the pattern of missing data in certain clinical variables is not at random but depends…

Machine Learning · Computer Science 2024-06-17 Hojjat Karami , David Atienza , Anisoara Ionescu

Electronic Health Records (EHRs) provide a wealth of information for machine learning algorithms to predict the patient outcome from the data including diagnostic information, vital signals, lab tests, drug administration, and demographic…

Machine Learning · Computer Science 2021-06-16 Byunggill Joe , Akshay Mehra , Insik Shin , Jihun Hamm

Electronic Health Records (EHR) are high-dimensional data with implicit connections among thousands of medical concepts. These connections, for instance, the co-occurrence of diseases and lab-disease correlations can be informative when…

Machine Learning · Computer Science 2021-03-29 Weicheng Zhu , Narges Razavian

Since clinical letters contain sensitive information, clinical-related datasets can not be widely applied in model training, medical research, and teaching. This work aims to generate reliable, various, and de-identified synthetic clinical…

Computation and Language · Computer Science 2024-09-17 Libo Ren , Samuel Belkadi , Lifeng Han , Warren Del-Pinto , Goran Nenadic

Despite the growing availability of Electronic Health Record (EHR) data, researchers often face substantial barriers in effectively using these data for translational research due to their complexity, heterogeneity, and lack of standardized…

Making the most use of abundant information in electronic health records (EHR) is rapidly becoming an important topic in the medical domain. Recent work presented a promising framework that embeds entire features in raw EHR data regardless…

Machine Learning · Computer Science 2023-05-11 Eunbyeol Cho , Min Jae Lee , Kyunghoon Hur , Jiyoun Kim , Jinsung Yoon , Edward Choi

The pivotal shift from traditional paper-based records to sophisticated Electronic Health Records (EHR), enabled systematic collection and analysis of patient data through descriptive statistics, providing insight into patterns and trends…

Artificial Intelligence · Computer Science 2025-02-18 Muhammet Alkan , Hester Huijsdens , Yola Jones , Fani Deligianni

Electronic health records (EHRs) are designed to synthesize diverse data types, including unstructured clinical notes, structured lab tests, and time-series visit data. Physicians draw on these multimodal and temporal sources of EHR data to…