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In this study, we propose MoME, a Mixture of Visual Language Medical Experts, for Medical Image Segmentation. MoME adapts the successful Mixture of Experts (MoE) paradigm, widely used in Large Language Models (LLMs), for medical…

Computer Vision and Pattern Recognition · Computer Science 2025-11-03 Arghavan Rezvani , Xiangyi Yan , Anthony T. Wu , Kun Han , Pooya Khosravi , Xiaohui Xie

Medical images are acquired at high resolutions with large fields of view in order to capture fine-grained features necessary for clinical decision-making. Consequently, training deep learning models on medical images can incur large…

Large language models (LLMs) and Vision-Language Models (VLMs) have been proven to excel at multiple tasks, such as commonsense reasoning. Powerful as these models can be, they are not grounded in the 3D physical world, which involves…

Computer Vision and Pattern Recognition · Computer Science 2023-07-25 Yining Hong , Haoyu Zhen , Peihao Chen , Shuhong Zheng , Yilun Du , Zhenfang Chen , Chuang Gan

With the advent of Vision-Language Models (VLMs), medical artificial intelligence (AI) has experienced significant technological progress and paradigm shifts. This survey provides an extensive review of recent advancements in Medical…

Computer Vision and Pattern Recognition · Computer Science 2025-03-05 Beria Chingnabe Kalpelbe , Angel Gabriel Adaambiik , Wei Peng

The recent integration of artificial intelligence into medical imaging has driven remarkable advances in automated organ segmentation. However, most existing 3D segmentation frameworks rely exclusively on visual learning from large…

Computer Vision and Pattern Recognition · Computer Science 2025-12-30 Hasan Faraz Khan , Noor Fatima , Muzammil Behzad

The rocketing prosperity of large language models (LLMs) in recent years has boosted the prevalence of vision-language models (VLMs) in the medical sector. In our online medical consultation scenario, a doctor responds to the texts and…

Multimodal large language models (MLLMs) enhance the capabilities of standard large language models by integrating and processing data from multiple modalities, including text, vision, audio, video, and 3D environments. Data plays a pivotal…

Artificial Intelligence · Computer Science 2024-07-19 Tianyi Bai , Hao Liang , Binwang Wan , Yanran Xu , Xi Li , Shiyu Li , Ling Yang , Bozhou Li , Yifan Wang , Bin Cui , Ping Huang , Jiulong Shan , Conghui He , Binhang Yuan , Wentao Zhang

Biological multimodal large language models (MLLMs) have emerged as powerful foundation models for scientific discovery. However, existing models are specialized to a single modality, limiting their ability to solve inherently cross-modal…

Machine Learning · Computer Science 2026-03-17 Wonbin Lee , Dongki Kim , Sung Ju Hwang

Existing volumetric medical image segmentation models are typically task-specific, excelling at specific target but struggling to generalize across anatomical structures or modalities. This limitation restricts their broader clinical use.…

Computer Vision and Pattern Recognition · Computer Science 2024-09-17 Haoyu Wang , Sizheng Guo , Jin Ye , Zhongying Deng , Junlong Cheng , Tianbin Li , Jianpin Chen , Yanzhou Su , Ziyan Huang , Yiqing Shen , Bin Fu , Shaoting Zhang , Junjun He , Yu Qiao

Multimodal Large Language Models (MLLMs) have tremendous potential to improve the accuracy, availability, and cost-effectiveness of healthcare by providing automated solutions or serving as aids to medical professionals. Despite promising…

Computer Vision and Pattern Recognition · Computer Science 2025-05-22 Mohammad Shahab Sepehri , Zalan Fabian , Maryam Soltanolkotabi , Mahdi Soltanolkotabi

Precise spatial modeling in the operating room (OR) is foundational to many clinical tasks, supporting intraoperative awareness, hazard avoidance, and surgical decision-making. While existing approaches leverage large-scale multimodal…

Computer Vision and Pattern Recognition · Computer Science 2025-08-12 Peiqi He , Zhenhao Zhang , Yixiang Zhang , Xiongjun Zhao , Shaoliang Peng

Recently, Large Language Models (LLMs) and Multimodal Large Language Models (MLLMs) have shown promise in instruction following and 2D image understanding. While these models are powerful, they have not yet been developed to comprehend the…

Computer Vision and Pattern Recognition · Computer Science 2023-12-22 Senqiao Yang , Jiaming Liu , Ray Zhang , Mingjie Pan , Zoey Guo , Xiaoqi Li , Zehui Chen , Peng Gao , Yandong Guo , Shanghang Zhang

3D medical image classification is essential for modern clinical workflows. Medical foundation models (FMs) have emerged as a promising approach for scaling to new tasks, yet current research suffers from three critical pitfalls:…

Computer Vision and Pattern Recognition · Computer Science 2026-05-28 Han Liu , Bogdan Georgescu , Yanbo Zhang , Youngjin Yoo , Michael Baumgartner , Riqiang Gao , Jianing Wang , Gengyan Zhao , Eli Gibson , Dorin Comaniciu , Sasa Grbic

Multimodal large language models (MLLMs) have advanced clinical tasks for common conditions, but their performance on rare diseases remains largely untested. In rare-disease scenarios, clinicians often lack prior clinical knowledge, forcing…

Computer Vision and Pattern Recognition · Computer Science 2026-05-14 Junzhi Ning , Jiashi Lin , Yingying Fang , Wei Li , Jiyao Liu , Cheng Tang , Chenglong Ma , Wenhao Tang , Tianbin Li , Ziyan Huang , Guang Yang , Junjun He

The application of the Multi-modal Large Language Models (MLLMs) in medical clinical scenarios remains underexplored. Previous benchmarks only focus on the capacity of the MLLMs in medical visual question-answering (VQA) or report…

Computation and Language · Computer Science 2024-08-19 Hongcheng Liu , Yusheng Liao , Siqv Ou , Yuhao Wang , Heyang Liu , Yanfeng Wang , Yu Wang

Vision-Language Pretraining (VLP) has demonstrated remarkable capabilities in learning visual representations from textual descriptions of images without annotations. Yet, effective VLP demands large-scale image-text pairs, a resource that…

Computer Vision and Pattern Recognition · Computer Science 2023-06-09 Yinda Chen , Che Liu , Wei Huang , Sibo Cheng , Rossella Arcucci , Zhiwei Xiong

Despite significant progress in pixel-level medical image analysis, existing medical image segmentation models rarely explore medical segmentation and diagnosis tasks jointly. However, it is crucial for patients that models can provide…

Computer Vision and Pattern Recognition · Computer Science 2025-11-11 Lingran Song , Yucheng Zhou , Jianbing Shen

Recent advances in multimodal large language models (LLMs) have highlighted their potential for medical and surgical applications. However, existing surgical datasets predominantly adopt a Visual Question Answering (VQA) format with…

Computer Vision and Pattern Recognition · Computer Science 2025-11-27 Tae-Min Choi , Tae Kyeong Jeong , Garam Kim , Jaemin Lee , Yeongyoon Koh , In Cheul Choi , Jae-Ho Chung , Jong Woong Park , Juyoun Park

In the real world, a molecule is a 3D geometric structure. Compared to 1D SMILES sequences and 2D molecular graphs, 3D molecules represent the most informative molecular modality. Despite the rapid progress of autoregressive-based language…

Computational Engineering, Finance, and Science · Computer Science 2025-08-15 Lei Jiang , Shuzhou Sun , Biqing Qi , Yuchen Fu , Xiaohua Xu , Yuqiang Li , Dongzhan Zhou , Tianfan Fu

In recent years, large language models (LLMs) have demonstrated remarkable potential across various medical applications. Building on this foundation, multimodal large language models (MLLMs) integrate LLMs with visual models to process…

Computation and Language · Computer Science 2025-03-11 Xiaoyi Liang , Mouxiao Bian , Moxin Chen , Lihao Liu , Junjun He , Jie Xu , Lin Li
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