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Related papers: Exploring Optimal Transport-Based Multi-Grained Al…

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Optimal transport (OT) is a powerful geometric tool used to compare and align probability measures following the least effort principle. Despite its widespread use in machine learning (ML), OT problem still bears its computational burden,…

Machine Learning · Computer Science 2023-08-14 Oliver Struckmeier , Ievgen Redko , Anton Mallasto , Karol Arndt , Markus Heinonen , Ville Kyrki

Autoregressive models (ARMs) have become the workhorse for sequence generation tasks, since many problems can be modeled as next-token prediction. While there appears to be a natural ordering for text (i.e., left-to-right), for many data…

Machine Learning · Computer Science 2025-07-15 Zhe Wang , Jiaxin Shi , Nicolas Heess , Arthur Gretton , Michalis K. Titsias

Multi-modal large language models (MLLMs) achieve strong visual-language reasoning but suffer from high inference cost due to redundant visual tokens. Recent work explores visual token pruning to accelerate inference, while existing pruning…

Computer Vision and Pattern Recognition · Computer Science 2026-04-02 Xiwen Chen , Wenhui Zhu , Gen Li , Xuanzhao Dong , Yujian Xiong , Hao Wang , Peijie Qiu , Qingquan Song , Zhipeng Wang , Shao Tang , Yalin Wang , Abolfazl Razi

Aligning electron density maps from Cryogenic electron microscopy (cryo-EM) is a first key step for studying multiple conformations of a biomolecule. As this step remains costly and challenging, with standard alignment tools being…

Biomolecules · Quantitative Biology 2022-10-19 A. Tajmir Riahi , G. Woollard , F. Poitevin , A. Condon , K. Dao Duc

Accurate extraction of molecular representations is a critical step in the drug discovery process. In recent years, significant progress has been made in molecular representation learning methods, among which multi-modal molecular…

Machine Learning · Computer Science 2025-05-13 Rong Yin , Ruyue Liu , Xiaoshuai Hao , Xingrui Zhou , Yong Liu , Can Ma , Weiping Wang

With the widespread application of optimal transport (OT), its calculation becomes essential, and various algorithms have emerged. However, the existing methods either have low efficiency or cannot represent discontinuous maps. A novel…

Computer Vision and Pattern Recognition · Computer Science 2023-11-14 Zezeng Li , Shenghao Li , Lianbao Jin , Na Lei , Zhongxuan Luo

Recently, learning open-vocabulary semantic segmentation from text supervision has achieved promising downstream performance. Nevertheless, current approaches encounter an alignment granularity gap owing to the absence of dense annotations,…

Computer Vision and Pattern Recognition · Computer Science 2024-03-07 Yajie Liu , Pu Ge , Qingjie Liu , Di Huang

Existing multimodal tasks mostly target at the complete input modality setting, i.e., each modality is either complete or completely missing in both training and test sets. However, the randomly missing situations have still been…

Computation and Language · Computer Science 2022-10-25 Wei Han , Hui Chen , Min-Yen Kan , Soujanya Poria

Cross-domain alignment between two sets of entities (e.g., objects in an image, words in a sentence) is fundamental to both computer vision and natural language processing. Existing methods mainly focus on designing advanced attention…

Computation and Language · Computer Science 2020-07-28 Liqun Chen , Zhe Gan , Yu Cheng , Linjie Li , Lawrence Carin , Jingjing Liu

Proteins are essential biological macromolecules that execute life functions. Local structural motifs, such as active sites, are the most critical components for linking structure to function and are key to understanding protein evolution…

Quantitative Methods · Quantitative Biology 2026-04-10 Zhiyu Wang , Bingxin Zhou , Jing Wang , Yang Tan , Weishu Zhao , Pietro Liò , Liang Hong

Despite the evolution of deep-learning-based visual-textual processing systems, precise multi-modal matching remains a challenging task. In this work, we tackle the task of cross-modal retrieval through image-sentence matching based on…

Computer Vision and Pattern Recognition · Computer Science 2021-03-03 Nicola Messina , Giuseppe Amato , Andrea Esuli , Fabrizio Falchi , Claudio Gennaro , Stéphane Marchand-Maillet

Retrieving tracked-vehicles by natural language descriptions plays a critical role in smart city construction. It aims to find the best match for the given texts from a set of tracked vehicles in surveillance videos. Existing works…

Computer Vision and Pattern Recognition · Computer Science 2022-05-10 Yunhao Du , Binyu Zhang , Xiangning Ruan , Fei Su , Zhicheng Zhao , Hong Chen

Multimodal molecular representation learning, which jointly models molecular graphs and their textual descriptions, enhances predictive accuracy and interpretability by enabling more robust and reliable predictions of drug toxicity,…

Machine Learning · Computer Science 2025-10-21 Yingxu Wang , Kunyu Zhang , Jiaxin Huang , Nan Yin , Siwei Liu , Eran Segal

The design of artificial neural networks (ANNs) is inspired by the structure of the human brain, and in turn, ANNs offer a potential means to interpret and understand brain signals. Existing methods primarily align brain signals with…

Neurons and Cognition · Quantitative Biology 2025-10-08 Yang Xiao , Wang Lu , Jie Ji , Ruimeng Ye , Gen Li , Xiaolong Ma , Bo Hui

Recent advancements in biology and chemistry have leveraged multi-modal learning, integrating molecules and their natural language descriptions to enhance drug discovery. However, current pre-training frameworks are limited to two…

Machine Learning · Computer Science 2025-02-05 Teng Xiao , Chao Cui , Huaisheng Zhu , Vasant G. Honavar

Aligning molecular sequence representations (e.g., SMILES notations) with textual descriptions is critical for applications spanning drug discovery, materials design, and automated chemical literature analysis. Existing methodologies…

Artificial Intelligence · Computer Science 2025-11-25 Letian Chen , Runhan Shi , Gufeng Yu , Yang Yang

Molecular representation learning plays a crucial role in various downstream tasks, such as molecular property prediction and drug design. To accurately represent molecules, Graph Neural Networks (GNNs) and Graph Transformers (GTs) have…

Machine Learning · Computer Science 2025-02-07 Jingjing Hu , Dan Guo , Zhan Si , Deguang Liu , Yunfeng Diao , Jing Zhang , Jinxing Zhou , Meng Wang

Large multimodal models (LMMs) have gained impressive performance due to their outstanding capability in various understanding tasks. However, these models still suffer from some fundamental limitations related to robustness and…

Computer Vision and Pattern Recognition · Computer Science 2025-11-27 Thanh-Dat Truong , Huu-Thien Tran , Tran Thai Son , Bhiksha Raj , Khoa Luu

Transferring linguistic knowledge from a pretrained language model (PLM) to acoustic feature learning has proven effective in enhancing end-to-end automatic speech recognition (E2E-ASR). However, aligning representations between linguistic…

Audio and Speech Processing · Electrical Eng. & Systems 2025-05-20 Xugang Lu , Peng Shen , Yu Tsao , Hisashi Kawai

Molecular knowledge resides within three different modalities of information sources: molecular structures, biomedical documents, and knowledge bases. Effective incorporation of molecular knowledge from these modalities holds paramount…

Biomolecules · Quantitative Biology 2023-07-24 Yizhen Luo , Kai Yang , Massimo Hong , Xing Yi Liu , Zaiqing Nie