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Accurate prediction of RNA-associated interactions is essential for understanding cellular regulation and advancing drug discovery. While Biological Large Language Models (BioLLMs) such as ESM-2 and RiNALMo provide powerful sequence…

Genomics · Quantitative Biology 2026-02-27 Rabeya Tus Sadia , Qiang Ye , Qiang Cheng

Mamba, a State Space Model (SSM), has recently shown competitive performance to Convolutional Neural Networks (CNNs) and Transformers in Natural Language Processing and general sequence modeling. Various attempts have been made to adapt…

Computer Vision and Pattern Recognition · Computer Science 2024-08-27 Trung Dinh Quoc Dang , Huy Hoang Nguyen , Aleksei Tiulpin

In recent developments, the Mamba architecture, known for its selective state space approach, has shown potential in the efficient modeling of long sequences. However, its application in image generation remains underexplored. Traditional…

Computer Vision and Pattern Recognition · Computer Science 2024-05-28 Shentong Mo , Yapeng Tian

Large Language Models (LLMs) are typically trained in two phases: pre-training on large internet-scale datasets, and fine-tuning for downstream tasks. Given the higher computational demand of pre-training, it's intuitive to assume that…

Machine Learning · Computer Science 2024-10-15 James Liu , Guangxuan Xiao , Kai Li , Jason D. Lee , Song Han , Tri Dao , Tianle Cai

Efficient long-context language modeling remains a significant challenge in Natural Language Processing (NLP). While Transformers dominate language tasks, they struggle with long sequences due to quadratic computational complexity in…

State space models (SSMs) are a promising alternative to transformers for language modeling because they use fixed memory during inference. However, this fixed memory usage requires some information loss in the hidden state when processing…

Computation and Language · Computer Science 2025-12-18 Tamanna Hossain , Robert L. Logan , Ganesh Jagadeesan , Sameer Singh , Joel Tetreault , Alejandro Jaimes

Large language models (LLMs) have made significant advances in complex reasoning tasks, yet they remain bottlenecked by two core challenges: architectural inefficiency due to reliance on Transformers, and a lack of structured fine-tuning…

Machine Learning · Computer Science 2025-05-29 Xueliang Zhao , Wei Wu , Lingpeng Kong

Recent work has shown that state space models such as Mamba are significantly worse than Transformers on recall-based tasks due to the fact that their state size is constant with respect to their input sequence length. But in practice,…

Machine Learning · Computer Science 2024-10-16 Asher Trockman , Hrayr Harutyunyan , J. Zico Kolter , Sanjiv Kumar , Srinadh Bhojanapalli

Recently, recurrent models based on linear state space models (SSMs) have shown promising performance in language modeling (LM), competititve with transformers. However, there is little understanding of the in-principle abilities of such…

Computation and Language · Computer Science 2025-12-15 Yash Sarrof , Yana Veitsman , Michael Hahn

Selective state space models (SSMs), such as Mamba, highly excel at capturing long-range dependencies in 1D sequential data, while their applications to 2D vision tasks still face challenges. Current visual SSMs often convert images into 1D…

Computer Vision and Pattern Recognition · Computer Science 2025-02-27 Chaodong Xiao , Minghan Li , Zhengqiang Zhang , Deyu Meng , Lei Zhang

Recently, state space models (SSM), particularly Mamba, have attracted significant attention from scholars due to their ability to effectively balance computational efficiency and performance. However, most existing visual Mamba methods…

Computer Vision and Pattern Recognition · Computer Science 2025-04-09 Leiye Liu , Miao Zhang , Jihao Yin , Tingwei Liu , Wei Ji , Yongri Piao , Huchuan Lu

State-space models (SSMs), particularly Mamba, emerge as an efficient Transformer alternative with linear complexity for long-sequence modeling. Recent empirical works demonstrate Mamba's in-context learning (ICL) capabilities competitive…

Machine Learning · Computer Science 2025-09-30 Jiarui Jiang , Wei Huang , Miao Zhang , Taiji Suzuki , Liqiang Nie

Image restoration requires simultaneously preserving fine-grained local structures and maintaining long-range spatial coherence. While convolutional networks struggle with limited receptive fields, and Transformers incur quadratic…

Computer Vision and Pattern Recognition · Computer Science 2026-03-11 Mohammed Hassanin , Nour Moustafa , Weijian Deng , Ibrahim Radwan

Transformers have become foundational for visual tasks such as object detection, semantic segmentation, and video understanding, but their quadratic complexity in attention mechanisms presents scalability challenges. To address these…

Computer Vision and Pattern Recognition · Computer Science 2025-02-12 Fady Ibrahim , Guangjun Liu , Guanghui Wang

Diffusion models have achieved great success in image generation, with the backbone evolving from U-Net to Vision Transformers. However, the computational cost of Transformers is quadratic to the number of tokens, leading to significant…

Computer Vision and Pattern Recognition · Computer Science 2024-07-11 Yao Teng , Yue Wu , Han Shi , Xuefei Ning , Guohao Dai , Yu Wang , Zhenguo Li , Xihui Liu

Designing computationally efficient network architectures remains an ongoing necessity in computer vision. In this paper, we adapt Mamba, a state-space language model, into VMamba, a vision backbone with linear time complexity. At the core…

Computer Vision and Pattern Recognition · Computer Science 2024-12-31 Yue Liu , Yunjie Tian , Yuzhong Zhao , Hongtian Yu , Lingxi Xie , Yaowei Wang , Qixiang Ye , Jianbin Jiao , Yunfan Liu

Recent advancements in imitation learning, particularly with the integration of LLM techniques, are set to significantly improve robots' dexterity and adaptability. This paper proposes using Mamba, a state-of-the-art architecture with…

Robotics · Computer Science 2024-09-26 Toshiaki Tsuji

Recent sequence modeling approaches using selective state space sequence models, referred to as Mamba models, have seen a surge of interest. These models allow efficient processing of long sequences in linear time and are rapidly being…

Machine Learning · Computer Science 2025-01-16 Farnoush Rezaei Jafari , Grégoire Montavon , Klaus-Robert Müller , Oliver Eberle

In recent years, the application of multimodal large language models (MLLM) in various fields has achieved remarkable success. However, as the foundation model for many downstream tasks, current MLLMs are composed of the well-known…

Computer Vision and Pattern Recognition · Computer Science 2025-01-09 Han Zhao , Min Zhang , Wei Zhao , Pengxiang Ding , Siteng Huang , Donglin Wang

We present StateSMix, a fully self-contained lossless compressor that couples an online-trained Mamba-style State Space Model (SSM) with sparse n-gram context mixing and arithmetic coding. The model is initialised from scratch and trained…

Machine Learning · Computer Science 2026-05-06 Roberto Tacconelli