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We present a rotation-equivariant unsupervised learning framework for the sparse deconvolution of non-negative scalar fields defined on the unit sphere. Spherical signals with multiple peaks naturally arise in Diffusion MRI (dMRI), where…

Image and Video Processing · Electrical Eng. & Systems 2021-02-19 Axel Elaldi , Neel Dey , Heejong Kim , Guido Gerig

We present Roto-Translation Equivariant Spherical Deconvolution (RT-ESD), an $E(3)\times SO(3)$ equivariant framework for sparse deconvolution of volumes where each voxel contains a spherical signal. Such 6D data naturally arises in…

Image and Video Processing · Electrical Eng. & Systems 2023-04-14 Axel Elaldi , Guido Gerig , Neel Dey

Convolutional networks are successful, but they have recently been outperformed by new neural networks that are equivariant under rotations and translations. These new networks work better because they do not struggle with learning each…

Computer Vision and Pattern Recognition · Computer Science 2021-02-16 Philip Müller , Vladimir Golkov , Valentina Tomassini , Daniel Cremers

We present a novel way to model diffusion magnetic resonance imaging (dMRI) datasets, that benefits from the structural coherence of the human brain while only using data from a single subject. Current methods model the dMRI signal in…

Image and Video Processing · Electrical Eng. & Systems 2023-08-24 Tom Hendriks , Anna Vilanova , Maxime Chamberland

The connectivity and structural integrity of the white matter of the brain is nowadays known to be implicated into a wide range of brain-related disorders. However, it was not before the advent of diffusion Magnetic Resonance Imaging (dMRI)…

Computer Vision and Pattern Recognition · Computer Science 2014-01-27 Q. Zhou , O. Michailovich , Y. Rathi

Diffusion magnetic resonance imaging is sensitive to the microstructural properties of brain tissue. However, estimating clinically and scientifically relevant microstructural properties from the measured signals remains a highly…

Image and Video Processing · Electrical Eng. & Systems 2024-02-27 Leevi Kerkelä , Kiran Seunarine , Filip Szczepankiewicz , Chris A. Clark

Early and accurate assessment of brain microstructure using diffusion Magnetic Resonance Imaging (dMRI) is crucial for identifying neurodevelopmental disorders in neonates, but remains challenging due to low signal-to-noise ratio (SNR),…

Computer Vision and Pattern Recognition · Computer Science 2025-10-15 Haykel Snoussi , Davood Karimi

We develop a general analytical and numerical framework for estimating intra- and extra-neurite water fractions and diffusion coefficients, as well as neurite orientational dispersion, in each imaging voxel. By employing a set of rotational…

Biological Physics · Physics 2018-04-10 Dmitry S. Novikov , Jelle Veraart , Ileana O. Jelescu , Els Fieremans

This paper demonstrates spherical convolutional neural networks (S-CNN) offer distinct advantages over conventional fully-connected networks (FCN) at estimating scalar parameters of tissue microstructure from diffusion MRI (dMRI). Such…

Image and Video Processing · Electrical Eng. & Systems 2022-08-17 Tobias Goodwin-Allcock , Jason McEwen , Robert Gray , Parashkev Nachev , Hui Zhang

Diffusion-weighted magnetic resonance imaging (DW-MRI) is the only non-invasive approach for estimation of intra-voxel tissue microarchitecture and reconstruction of in vivo neural pathways for the human brain. With improvement in…

Image and Video Processing · Electrical Eng. & Systems 2020-02-21 Vishwesh Nath , Sudhir K. Pathak , Kurt G. Schilling , Walt Schneider , Bennett A. Landman

Diffusion-weighted magnetic resonance imaging (DW-MRI) is a critical imaging method for capturing and modeling tissue microarchitecture at a millimeter scale. A common practice to model the measured DW-MRI signal is via fiber orientation…

Analyzing scalar and vector fields on the sphere, such as temperature or wind speed and direction on Earth, is a difficult task. Models should respect both the rotational symmetries of the sphere and the inherent symmetries of the vector…

Machine Learning · Computer Science 2026-04-01 Francesco Ballerin , Nello Blaser , Erlend Grong

Diffusion-weighted magnetic resonance imaging allows for reconstruction of models for structural connectivity in the brain, such as fiber orientation distribution functions (ODFs) that describe the distribution, direction, and volume of…

Confocal histology provides an opportunity to establish intra-voxel fiber orientation distributions that can be used to quantitatively assess the biological relevance of diffusion weighted MRI models, e.g., constrained spherical…

Diffusion Magnetic Resonance Imaging (dMRI) plays a crucial role in the noninvasive investigation of tissue microstructural properties and structural connectivity in the \textit{in vivo} human brain. However, to effectively capture the…

Computer Vision and Pattern Recognition · Computer Science 2024-01-04 Jing Yang , Jian Cheng , Cheng Li , Wenxin Fan , Juan Zou , Ruoyou Wu , Shanshan Wang

Diffusion MRI (dMRI) provides the ability to reconstruct neuronal fibers in the brain, $\textit{in vivo}$, by measuring water diffusion along angular gradient directions in q-space. High angular resolution diffusion imaging (HARDI) can…

Machine Learning · Statistics 2018-05-30 Evan Schwab , René Vidal , Nicolas Charon

Fiber tractography is an important tool of computational neuroscience that enables reconstructing the spatial connectivity and organization of white matter of the brain. Fiber tractography takes advantage of diffusion Magnetic Resonance…

Image and Video Processing · Electrical Eng. & Systems 2020-09-08 Tomer Weiss , Sanketh Vedula , Ortal Senouf , Oleg Michailovich , AlexBronstein

High spatio-angular resolution diffusion MRI (dMRI) has been shown to provide accurate identification of complex neuronal fiber configurations, albeit, at the cost of long acquisition times. We propose a method to recover intra-voxel fiber…

Image and Video Processing · Electrical Eng. & Systems 2021-12-07 Marica Pesce , Audrey Repetti , Anna Auría , Alessandro Daducci , Jean-Philippe Thiran , Yves Wiaux

Spherical data is found in many applications. By modeling the discretized sphere as a graph, we can accommodate non-uniformly distributed, partial, and changing samplings. Moreover, graph convolutions are computationally more efficient than…

Machine Learning · Computer Science 2019-04-11 Michaël Defferrard , Nathanaël Perraudin , Tomasz Kacprzak , Raphael Sgier

Diffusion-weighted MRI measures the direction and scale of the local diffusion process in every voxel through its spectrum in q-space, typically acquired in one or more shells. Recent developments in microstructure imaging and multi-tissue…

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